Detailed information of TA system TA044143

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/RelE-YefM
• Location: 1548172..1548713
• Replicon: chromosome
• Accession: NZ_AP027735
• Organism: Barrientosiimonas endolithica strain NBRC 110608

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: QUE40_RS07830
• Protein ID: WP_289232799.1
• Coordinates: 1548172..1548375 (-)
• Length: 68 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: QUE40_RS07835
• Protein ID: WP_142005167.1
• Coordinates: 1548435..1548713 (-)
• Length: 93 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
QUE40_RS07790 (GCM10025872_16290)	1543649..1544116	+	468	WP_289232792.1	DUF1772 domain-containing protein	-
QUE40_RS07795 (GCM10025872_16300)	1544192..1545022	+	831	WP_289232793.1	nucleotidyltransferase domain-containing protein	-
QUE40_RS07800 (GCM10025872_16310)	1545011..1546021	-	1011	WP_289232794.1	phosphotransferase	-
QUE40_RS07805 (GCM10025872_16320)	1546127..1546354	+	228	WP_289232795.1	type II toxin-antitoxin system prevent-host-death family antitoxin	-
QUE40_RS07810	1546410..1546807	+	398	Protein_1539	type II toxin-antitoxin system VapC family toxin	-
QUE40_RS07815 (GCM10025872_16340)	1546794..1547351	-	558	WP_289232796.1	GrpB family protein	-
QUE40_RS07820	1547496..1547633	+	138	WP_289232797.1	hypothetical protein	-
QUE40_RS07825 (GCM10025872_16350)	1547630..1548031	+	402	WP_289232798.1	GNAT family N-acetyltransferase	-
QUE40_RS07830 (GCM10025872_16360)	1548172..1548375	-	204	WP_289232799.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
QUE40_RS07835 (GCM10025872_16370)	1548435..1548713	-	279	WP_142005167.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin
QUE40_RS07840 (GCM10025872_16380)	1548804..1549232	-	429	WP_289232800.1	hypothetical protein	-
QUE40_RS07845 (GCM10025872_16390)	1549306..1549905	-	600	WP_289232801.1	DUF418 domain-containing protein	-
QUE40_RS07850 (GCM10025872_16400)	1550416..1550751	+	336	WP_289232802.1	TraR/DksA C4-type zinc finger protein	-
QUE40_RS07855 (GCM10025872_16410)	1551310..1551888	-	579	WP_289232803.1	DinB family protein	-
QUE40_RS07860 (GCM10025872_16420)	1551929..1552681	-	753	WP_289232804.1	methyltransferase domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Genomic island	-	-	1547663..1557104	9441

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (16-64)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (3-75)

Sequences

Toxin

Protein

• Length: 68 a.a.
• Molecular weight: 7677.72 Da
• Isoelectric Point: 9.9759

>T44143 WP_289232799.1 NZ_AP027735:c1548375-1548172 [Barrientosiimonas endolithica]
VTPAIIEFIYGPLVGNPHRVGKPLRDDSEGQWSARRGDYRILYVIDDQAQEVVVSRIGHRARVYKSR

Nucleotide

• Length: 204 bp

>T44143 NZ_AP027735:c1548375-1548172 [Barrientosiimonas endolithica]
GTGACCCCGGCGATCATCGAGTTCATCTACGGCCCGCTGGTCGGCAACCCTCACCGCGTCGGCAAGCCTCTTCGCGATGA
CTCCGAAGGGCAGTGGTCGGCACGGCGCGGCGACTACCGCATCCTGTACGTGATCGACGACCAGGCGCAGGAAGTCGTCG
TGAGCCGAATCGGGCACCGGGCGCGGGTCTACAAGTCACGATGA

Antitoxin

Protein

• Length: 93 a.a.
• Molecular weight: 10212.40 Da
• Isoelectric Point: 4.9314

>AT44143 WP_142005167.1 NZ_AP027735:c1548713-1548435 [Barrientosiimonas endolithica]
MSTTLPLTEAKAKLNELIDSAVNTHERVTITRRGKPAAVLISVEDLESIEETLHWQSQPGAREASDEALAERERGELWDE
GAVRRRYGVGKA

Nucleotide

• Length: 279 bp

>AT44143 NZ_AP027735:c1548713-1548435 [Barrientosiimonas endolithica]
ATGAGCACGACGCTGCCGCTGACCGAAGCCAAGGCGAAGCTGAACGAGTTGATCGACTCCGCCGTGAACACCCACGAACG
AGTGACCATCACCCGTCGAGGCAAGCCTGCGGCCGTGCTGATCTCGGTGGAGGACCTGGAGTCCATCGAGGAGACGTTGC
ACTGGCAGTCGCAGCCCGGCGCGCGCGAGGCGTCCGACGAGGCTCTGGCCGAGCGCGAGCGAGGCGAACTGTGGGATGAA
GGAGCCGTCCGCCGCCGGTATGGCGTAGGGAAGGCGTGA