Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 1319269..1319903 Replicon chromosome
Accession NZ_AP027729
Organism Paraoerskovia sediminicola strain NBRC 108565

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag QUE47_RS06285 Protein ID WP_286219053.1
Coordinates 1319496..1319903 (+) Length 136 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag QUE47_RS06280 Protein ID WP_286219052.1
Coordinates 1319269..1319499 (+) Length 77 a.a.

Genomic Context

QUE47_RS06255QUE47_RS06260QUE47_RS06265QUE47_RS06270QUE47_RS06275QUE47_RS06280QUE47_RS06285QUE47_RS06290QUE47_RS06295QUE47_RS06300QUE47_RS06305QUE47_RS06310
Location: 1314302..1315603 (1302 bp)
Type: Others
Protein ID: WP_286219047.1
Location: 1315713..1316561 (849 bp)
Type: Others
Protein ID: WP_286219048.1
Location: 1316558..1317292 (735 bp)
Type: Others
Protein ID: WP_286219049.1
Location: 1317289..1318029 (741 bp)
Type: Others
Protein ID: WP_286219050.1
Location: 1318083..1319048 (966 bp)
Type: Others
Protein ID: WP_286219051.1
Location: 1319269..1319499 (231 bp)
Type: Antitoxin
Protein ID: WP_286219052.1
Location: 1319496..1319903 (408 bp)
Type: Toxin
Protein ID: WP_286219053.1
Location: 1319893..1320438 (546 bp)
Type: Others
Protein ID: WP_286219054.1
Location: 1320509..1321069 (561 bp)
Type: Others
Protein ID: WP_286219055.1
Location: 1321135..1322118 (984 bp)
Type: Others
Protein ID: WP_286219056.1
Location: 1322265..1323974 (1710 bp)
Type: Others
Protein ID: WP_286219057.1
Location: 1323989..1324257 (269 bp)
Type: Others
Protein ID: Protein_1242
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
QUE47_RS06255 (GCM10025865_12760)1314302..1315603+1302WP_286219047.1dipeptidase-
QUE47_RS06260 (GCM10025865_12770)1315713..1316561+849WP_286219048.1ATP-binding cassette domain-containing protein-
QUE47_RS06265 (GCM10025865_12780)1316558..1317292+735WP_286219049.1ABC transporter permease-
QUE47_RS06270 (GCM10025865_12790)1317289..1318029+741WP_286219050.1ABC transporter permease-
QUE47_RS06275 (GCM10025865_12800)1318083..1319048+966WP_286219051.1ABC transporter substrate-binding protein-
QUE47_RS06280 (GCM10025865_12810)1319269..1319499+231WP_286219052.1type II toxin-antitoxin system VapB family antitoxinAntitoxin
QUE47_RS06285 (GCM10025865_12820)1319496..1319903+408WP_286219053.1type II toxin-antitoxin system VapC family toxinToxin
QUE47_RS06290 (GCM10025865_12830)1319893..1320438-546WP_286219054.1YbaK/EbsC family protein-
QUE47_RS06295 (GCM10025865_12840)1320509..1321069-561WP_286219055.1hypothetical protein-
QUE47_RS06300 (GCM10025865_12850)1321135..1322118-984WP_286219056.1aldo/keto reductase-
QUE47_RS06305 (GCM10025865_12860)1322265..1323974-1710WP_286219057.1phosphoenolpyruvate--protein phosphotransferase-
QUE47_RS063101323989..1324257-269Protein_1242HPr family phosphocarrier protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(5-125)

Antitoxin

SpoVT-AbrB domain

(6-51)


Sequences

Toxin        


Download         Length: 136 a.a.        Molecular weight: 14876.96 Da        Isoelectric Point: 5.6855

>T44136 WP_286219053.1 NZ_AP027729:1319496-1319903 [Paraoerskovia sediminicola]
VTTLYLLDTNILIALLRRRADAARPRLRAAEGRIAVSTISEAELDYGIERSRHAEQNRQAVDELLSLVEVVPFDSTAAMH
AGRVRAVLADRGEPIGPYDTLLAGHARSLGLVMVTNNVREFSRVPGLEVEDWLSC

Download         Length: 408 bp

>T44136 NZ_AP027729:1319496-1319903 [Paraoerskovia sediminicola]
GTGACGACGCTCTACCTGCTCGACACCAACATCCTCATCGCGCTCCTGCGCAGACGCGCCGATGCGGCCCGTCCGAGGCT
CCGCGCGGCCGAGGGACGCATCGCGGTCTCGACGATCAGCGAGGCAGAGCTGGACTACGGGATCGAGCGCTCCCGGCACG
CCGAGCAGAACCGTCAGGCGGTCGACGAGCTGCTGAGCCTTGTGGAGGTCGTACCGTTCGACTCGACCGCAGCGATGCAT
GCCGGCCGGGTCCGTGCGGTCCTCGCCGACCGGGGAGAGCCGATCGGGCCGTACGACACGCTCCTCGCCGGTCACGCACG
GTCGCTCGGCCTGGTCATGGTGACGAACAACGTCCGGGAGTTCTCGCGAGTGCCAGGACTCGAAGTCGAGGACTGGCTCA
GCTGCTGA

Antitoxin


Download         Length: 77 a.a.        Molecular weight: 8436.48 Da        Isoelectric Point: 5.7906

>AT44136 WP_286219052.1 NZ_AP027729:1319269-1319499 [Paraoerskovia sediminicola]
MRTTVFLNNRTQAVRLPKALALPDGTREVNVRAVGRSRVIEPVGSSWDGWFEHGPFAADDFLVDRDQGVAEERAAL

Download         Length: 231 bp

>AT44136 NZ_AP027729:1319269-1319499 [Paraoerskovia sediminicola]
ATGAGAACCACAGTGTTTCTCAACAACCGCACGCAGGCGGTGCGCCTGCCCAAGGCGCTCGCCCTGCCCGACGGCACCCG
CGAGGTCAACGTCCGCGCGGTCGGCCGCTCGCGCGTGATCGAGCCGGTCGGTTCGTCGTGGGACGGCTGGTTCGAGCACG
GCCCGTTCGCCGCCGACGACTTTCTCGTCGACCGCGACCAGGGCGTCGCCGAAGAGCGCGCGGCTCTGTGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References