Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN(toxin)
Location 11440..12101 Replicon chromosome
Accession NZ_AP027729
Organism Paraoerskovia sediminicola strain NBRC 108565

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag QUE47_RS00070 Protein ID WP_286218059.1
Coordinates 11673..12101 (+) Length 143 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag QUE47_RS00065 Protein ID WP_286218058.1
Coordinates 11440..11676 (+) Length 79 a.a.

Genomic Context

QUE47_RS00045QUE47_RS00050QUE47_RS00055QUE47_RS00060QUE47_RS00065QUE47_RS00070QUE47_RS00075QUE47_RS00080QUE47_RS00090QUE47_RS00095QUE47_RS00085QUE47_RS00100QUE47_RS00105
Location: 6572..7693 (1122 bp)
Type: Others
Protein ID: WP_286218057.1
Location: 8183..9190 (1008 bp)
Type: Others
Protein ID: WP_286219550.1
Location: 9456..10441 (986 bp)
Type: Others
Protein ID: Protein_10
Location: 10591..11354 (764 bp)
Type: Others
Protein ID: Protein_11
Location: 11440..11676 (237 bp)
Type: Antitoxin
Protein ID: WP_286218058.1
Location: 11673..12101 (429 bp)
Type: Toxin
Protein ID: WP_286218059.1
Location: 12152..12594 (443 bp)
Type: Others
Protein ID: Protein_14
Location: 12591..12686 (96 bp)
Type: Others
Protein ID: Protein_15
Location: 13417..14010 (594 bp)
Type: Others
Protein ID: WP_286218061.1
Location: 14015..15172 (1158 bp)
Type: Others
Protein ID: WP_286218062.1
Location: 12763..13350 (588 bp)
Type: Others
Protein ID: WP_286218060.1
Location: 15162..15911 (750 bp)
Type: Others
Protein ID: WP_286218063.1
Location: 15988..16815 (828 bp)
Type: Others
Protein ID: WP_286218064.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
QUE47_RS00045 (GCM10025865_00060)6572..7693+1122WP_286218057.1glutathione S-transferase C-terminal domain-containing protein-
QUE47_RS00050 (GCM10025865_00070)8183..9190+1008WP_286219550.1putative F420-0 ABC transporter substrate-binding protein-
QUE47_RS000559456..10441+986Protein_10iron chelate uptake ABC transporter family permease subunit-
QUE47_RS0006010591..11354+764Protein_11ATP-binding cassette domain-containing protein-
QUE47_RS00065 (GCM10025865_00100)11440..11676+237WP_286218058.1YlcI/YnfO family proteinAntitoxin
QUE47_RS00070 (GCM10025865_00110)11673..12101+429WP_286218059.1PIN domain-containing proteinToxin
QUE47_RS00075 (GCM10025865_00120)12152..12594+443Protein_14VOC family protein-
QUE47_RS0008012591..12686+96Protein_15Fe-S cluster assembly protein HesB-
QUE47_RS00085 (GCM10025865_00130)12763..13350-588WP_286218060.1hypothetical protein-
QUE47_RS00090 (GCM10025865_00140)13417..14010+594WP_286218061.1HhH-GPD-type base excision DNA repair protein-
QUE47_RS00095 (GCM10025865_00150)14015..15172+1158WP_286218062.12-phospho-L-lactate transferase CofD family protein-
QUE47_RS00100 (GCM10025865_00160)15162..15911-750WP_286218063.12-phospho-L-lactate guanylyltransferase-
QUE47_RS00105 (GCM10025865_00170)15988..16815-828WP_286218064.1coenzyme F420-0:L-glutamate ligase-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(5-133)

Antitoxin

CopG-like ribbon-helix-helix domain

(2-31)


Sequences

Toxin        


Download         Length: 143 a.a.        Molecular weight: 15169.53 Da        Isoelectric Point: 7.1724

>T44135 WP_286218059.1 NZ_AP027729:11673-12101 [Paraoerskovia sediminicola]
MIAPDVTVLVGALVARHPHKHVCEPWLTAAIANPEPLALTDAVLGATVRILTHRRIYPNPLPATAALDLVEGLLAAPGTI
RIGPGPRHWEIFGQLCRGSDVHGNLVADAQHASVAIEHGATWATLDRDFARFPGLRVVDPRA

Download         Length: 429 bp

>T44135 NZ_AP027729:11673-12101 [Paraoerskovia sediminicola]
ATGATCGCTCCGGACGTCACCGTCCTCGTCGGCGCACTCGTCGCACGCCATCCGCACAAGCACGTGTGCGAGCCGTGGCT
GACCGCGGCGATCGCGAACCCCGAACCGCTCGCTCTCACGGACGCCGTCCTCGGTGCCACGGTGCGGATCCTCACCCACC
GGCGCATCTACCCGAACCCGCTGCCCGCCACTGCCGCGCTCGACCTCGTCGAGGGCCTGCTGGCCGCACCGGGGACCATC
CGGATCGGGCCGGGGCCGCGCCACTGGGAGATCTTCGGGCAGCTCTGCCGGGGCTCCGACGTCCACGGAAACCTGGTCGC
CGACGCACAGCACGCCTCCGTCGCGATCGAGCACGGCGCGACGTGGGCGACGCTCGACCGGGACTTCGCCCGGTTCCCCG
GTCTGCGCGTCGTCGACCCGCGCGCCTGA

Antitoxin


Download         Length: 79 a.a.        Molecular weight: 8710.88 Da        Isoelectric Point: 4.7683

>AT44135 WP_286218058.1 NZ_AP027729:11440-11676 [Paraoerskovia sediminicola]
MRTTLHLPDDLYRDVKRTAAQEGRTVTSLVEDALREELRRRTAAPGRPYVVPTVDLGDPLVEIDMTSNAAMLDAMDGR

Download         Length: 237 bp

>AT44135 NZ_AP027729:11440-11676 [Paraoerskovia sediminicola]
ATGAGGACCACTCTGCACCTGCCCGACGACCTCTACCGGGACGTCAAGCGCACCGCCGCGCAGGAGGGACGCACCGTCAC
GTCGCTCGTCGAGGACGCGCTGCGCGAAGAGCTGCGCAGGCGGACCGCCGCTCCCGGTCGGCCGTACGTCGTCCCGACCG
TCGACCTCGGAGACCCCCTCGTCGAGATCGACATGACGAGCAACGCCGCGATGCTCGACGCGATGGACGGCCGATGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References