Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC(toxin)
Location 2213893..2214551 Replicon chromosome
Accession NZ_AP027728
Organism Microbacterium suwonense strain NBRC 106310

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag QUE33_RS11030 Protein ID WP_286299994.1
Coordinates 2213893..2214291 (-) Length 133 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag QUE33_RS11035 Protein ID WP_286299996.1
Coordinates 2214288..2214551 (-) Length 88 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QUE33_RS11010 (GCM10025863_22980) 2208895..2210310 - 1416 WP_286303150.1 MFS transporter -
QUE33_RS11015 (GCM10025863_22990) 2210430..2211089 - 660 WP_286299985.1 PadR family transcriptional regulator -
QUE33_RS11020 (GCM10025863_23000) 2211203..2212882 - 1680 WP_286299988.1 lipase family protein -
QUE33_RS11025 (GCM10025863_23010) 2212980..2213888 + 909 WP_286299991.1 phosphoribosylaminoimidazolesuccinocarboxamide synthase -
QUE33_RS11030 (GCM10025863_23020) 2213893..2214291 - 399 WP_286299994.1 type II toxin-antitoxin system VapC family toxin Toxin
QUE33_RS11035 (GCM10025863_23030) 2214288..2214551 - 264 WP_286299996.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
QUE33_RS11040 (GCM10025863_23040) 2214699..2216027 + 1329 WP_286299998.1 solute carrier family 23 protein -
QUE33_RS11045 (GCM10025863_23050) 2216095..2217708 - 1614 WP_286300000.1 urea amidolyase family protein -
QUE33_RS11050 (GCM10025863_23060) 2217718..2218494 - 777 WP_286300002.1 5-oxoprolinase subunit PxpA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(1-124)

Antitoxin

Antitoxin VapB-like

(1-86)


Sequences

Toxin        


Download         Length: 133 a.a.        Molecular weight: 14054.03 Da        Isoelectric Point: 5.1687

>T44134 WP_286299994.1 NZ_AP027728:c2214291-2213893 [Microbacterium suwonense]
MIVDSSVFVAVLLDETEGPGLATKLNAKTVVVSAATLTETSIVLRGRAGDQMVAKLDELLSGIGATIAPVDERQARIAVD
AHRRYGRGSGHPAKLNYGDCFSYALAIARDEPLLFKGDDFVHTDVRVVASEI

Download         Length: 399 bp

>T44134 NZ_AP027728:c2214291-2213893 [Microbacterium suwonense]
ATGATCGTCGATTCATCCGTCTTCGTCGCGGTGCTGCTTGACGAAACCGAAGGCCCTGGATTGGCGACCAAGCTGAATGC
GAAAACTGTCGTCGTTTCGGCGGCGACCCTGACGGAGACATCGATCGTGCTCCGCGGACGGGCGGGTGATCAGATGGTTG
CGAAGCTGGACGAACTCCTGAGCGGTATCGGTGCGACCATCGCGCCCGTAGACGAGCGTCAGGCTCGCATAGCGGTCGAC
GCTCACCGTCGCTACGGTCGAGGCTCCGGGCATCCGGCCAAGCTCAACTACGGTGACTGCTTCAGCTACGCGCTCGCGAT
CGCGCGCGATGAGCCGCTGCTGTTCAAGGGCGACGATTTCGTGCACACCGACGTGCGAGTCGTGGCATCGGAGATCTGA

Antitoxin


Download         Length: 88 a.a.        Molecular weight: 9862.22 Da        Isoelectric Point: 10.1819

>AT44134 WP_286299996.1 NZ_AP027728:c2214551-2214288 [Microbacterium suwonense]
MSLNIKNERVHDLVRQLAAQTGQSMTSAIEDAVRRRLEEVNGTREAEIARRRAAIDRIVASARLIPRTAKSTAEIMDEMY
DDRGLPR

Download         Length: 264 bp

>AT44134 NZ_AP027728:c2214551-2214288 [Microbacterium suwonense]
ATGAGCCTGAACATCAAGAACGAGAGAGTGCACGATCTCGTTCGTCAGCTCGCCGCGCAGACCGGCCAGTCCATGACGAG
TGCGATCGAGGATGCCGTGCGTCGGCGGCTCGAGGAGGTGAACGGCACTCGTGAGGCGGAGATCGCGCGACGTCGTGCCG
CGATTGATCGGATCGTGGCGAGTGCGCGGCTGATCCCACGCACAGCGAAGTCCACCGCGGAGATCATGGACGAGATGTAC
GACGACAGGGGGCTGCCGCGATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References