Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 306654..306925 Replicon chromosome
Accession NZ_AP027440
Organism Escherichia coli strain EC556 isolate EC556

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 306784..306887 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 306654..306925 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QUE77_RS02930 303209..303871 - 663 WP_000944256.1 exodeoxyribonuclease X -
QUE77_RS02935 303895..304551 - 657 WP_000011651.1 carbon-nitrogen hydrolase family protein YobB -
QUE77_RS02940 304653..304883 - 231 WP_000916763.1 DNA polymerase III subunit theta -
QUE77_RS02945 305022..305396 + 375 WP_000204705.1 CopC domain-containing protein YobA -
QUE77_RS02950 305400..306272 + 873 WP_000879330.1 copper homeostasis membrane protein CopD -
QUE77_RS02955 306285..306626 + 342 WP_000976472.1 YebY family protein -
- 306654..306925 - 272 - - Antitoxin
- 306784..306887 + 104 - - Toxin
QUE77_RS02960 307022..307678 + 657 WP_001520704.1 protein-serine/threonine phosphatase -
QUE77_RS02965 307679..307870 - 192 WP_001296140.1 YebW family protein -
QUE77_RS02970 307975..308211 - 237 WP_001295499.1 YebV family protein -
QUE77_RS02975 308329..309768 - 1440 WP_024166480.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 282871..328142 45271


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T44074 NZ_AP027440:306784-306887 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT44074 NZ_AP027440:c306925-306654 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGCCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References