Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 4048883..4049154 Replicon chromosome
Accession NZ_AP027411
Organism Escherichia coli strain EC521 isolate EC521

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 4049013..4049116 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 4048883..4049154 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QUE69_RS20210 4045438..4046100 - 663 WP_213831593.1 exodeoxyribonuclease X -
QUE69_RS20215 4046124..4046780 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein YobB -
QUE69_RS20220 4046882..4047112 - 231 WP_000916763.1 DNA polymerase III subunit theta -
QUE69_RS20225 4047251..4047625 + 375 WP_000168747.1 CopC domain-containing protein YobA -
QUE69_RS20230 4047629..4048501 + 873 WP_000879289.1 copper homeostasis membrane protein CopD -
QUE69_RS20235 4048514..4048855 + 342 WP_000976476.1 YebY family protein -
- 4048883..4049154 - 272 - - Antitoxin
- 4049013..4049116 + 104 - - Toxin
QUE69_RS20240 4049251..4049907 + 657 WP_000812724.1 protein-serine/threonine phosphatase -
QUE69_RS20245 4049908..4050099 - 192 WP_000457842.1 YebW family protein -
QUE69_RS20250 4050204..4050440 - 237 WP_001295499.1 YebV family protein -
QUE69_RS20255 4050558..4051997 - 1440 WP_001352260.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T43850 NZ_AP027411:4049013-4049116 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT43850 NZ_AP027411:c4049154-4048883 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References