Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/ParE-RHH
Location 2787572..2788104 Replicon chromosome
Accession NZ_AP027364
Organism Thalassotalea atypica strain JCM 31894

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag QUE03_RS12835 Protein ID WP_286262058.1
Coordinates 2787572..2787865 (-) Length 98 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag QUE03_RS12840 Protein ID WP_286262060.1
Coordinates 2787865..2788104 (-) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QUE03_RS12810 2783715..2784503 + 789 WP_286262049.1 hypothetical protein -
QUE03_RS12815 2784657..2785244 + 588 WP_286262051.1 hypothetical protein -
QUE03_RS12820 2785406..2785621 + 216 WP_286262053.1 hypothetical protein -
QUE03_RS12825 2785715..2786907 + 1193 Protein_2486 IS3 family transposase -
QUE03_RS12830 2787038..2787529 + 492 WP_286262055.1 hypothetical protein -
QUE03_RS12835 2787572..2787865 - 294 WP_286262058.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
QUE03_RS12840 2787865..2788104 - 240 WP_286262060.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
QUE03_RS12845 2788298..2788720 - 423 WP_286267846.1 MarR family transcriptional regulator -
QUE03_RS12850 2788844..2789341 + 498 WP_286262062.1 cytochrome P460 family protein -
QUE03_RS12855 2789740..2789988 - 249 Protein_2492 transposase -
QUE03_RS12860 2790232..2790693 + 462 WP_286262064.1 nuclear transport factor 2 family protein -
QUE03_RS12865 2791554..2791715 + 162 WP_286262066.1 YqaE/Pmp3 family membrane protein -
QUE03_RS12870 2791881..2792723 + 843 WP_286262069.1 MBL fold metallo-hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-92)

Antitoxin

Antitoxin ParD

(1-78)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 11234.06 Da        Isoelectric Point: 10.1495

>T43771 WP_286262058.1 NZ_AP027364:c2787865-2787572 [Thalassotalea atypica]
MSKFELSGKAKSDLIKIAKYTQLTWGTAQRDDYLKLLDNTFHQLAGEPMLAVNCDYIREGYRKRPQGSHIIYYKAHKANQ
ILIVRILHKSIDVNRAL

Download         Length: 294 bp

>T43771 NZ_AP027364:c2787865-2787572 [Thalassotalea atypica]
ATGTCGAAATTCGAATTATCAGGTAAAGCCAAAAGTGATTTAATTAAAATAGCCAAATATACTCAATTAACTTGGGGAAC
AGCACAAAGGGATGATTACTTAAAACTGTTAGATAATACTTTCCATCAACTAGCAGGTGAACCGATGCTAGCAGTTAATT
GCGATTATATAAGAGAAGGTTACCGAAAACGTCCTCAAGGTAGCCACATAATTTATTATAAAGCGCACAAAGCAAACCAA
ATTTTGATTGTAAGAATATTACACAAGAGTATAGATGTTAACCGCGCGCTCTGA

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 8864.81 Da        Isoelectric Point: 4.5515

>AT43771 WP_286262060.1 NZ_AP027364:c2788104-2787865 [Thalassotalea atypica]
MAKNTSVTLGEHFDQFINQQLNSGRYGSASEVVRAGLRVLEDQETKIMNLRKMLVEGENSGVADYSYDSLISELDKDNH

Download         Length: 240 bp

>AT43771 NZ_AP027364:c2788104-2787865 [Thalassotalea atypica]
ATGGCTAAAAATACGAGCGTAACATTAGGCGAGCATTTTGATCAATTTATAAATCAGCAACTTAACTCAGGTCGTTATGG
TTCAGCAAGTGAAGTTGTGCGCGCTGGTTTAAGAGTCTTGGAAGATCAGGAAACAAAGATAATGAATTTACGCAAAATGC
TAGTTGAAGGTGAAAACAGTGGCGTTGCAGATTACTCATATGATTCTTTGATTTCAGAGCTGGATAAAGATAACCATTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References