Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/RHH(antitoxin)
Location 3321554..3322092 Replicon chromosome
Accession NZ_AP027363
Organism Thalassotalea agarivorans strain JCM 13379

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag QUD85_RS15115 Protein ID WP_093330687.1
Coordinates 3321793..3322092 (+) Length 100 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag QUD85_RS15110 Protein ID WP_093330862.1
Coordinates 3321554..3321796 (+) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QUD85_RS15095 3316851..3318098 + 1248 WP_093330672.1 HlyD family efflux transporter periplasmic adaptor subunit -
QUD85_RS15100 3318515..3318736 + 222 WP_093330674.1 hypothetical protein -
QUD85_RS15105 3319256..3321391 + 2136 WP_093330683.1 peptidase domain-containing ABC transporter -
QUD85_RS15110 3321554..3321796 + 243 WP_093330862.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
QUD85_RS15115 3321793..3322092 + 300 WP_093330687.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
QUD85_RS15120 3322205..3322609 - 405 WP_093330689.1 thioesterase family protein -
QUD85_RS15125 3322813..3324207 + 1395 WP_093330693.1 TolC family protein -
QUD85_RS15130 3324207..3325181 + 975 WP_093330696.1 efflux RND transporter periplasmic adaptor subunit -
QUD85_RS15135 3325194..3326348 + 1155 WP_093330698.1 ABC transporter permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-90)

Antitoxin

Antitoxin ParD

(1-76)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11489.30 Da        Isoelectric Point: 9.7721

>T43770 WP_093330687.1 NZ_AP027363:3321793-3322092 [Thalassotalea agarivorans]
VNLFLLSNKAKNDLGNIALFSYHRWGKEQRNIYIRQFDEAFGLLAKNPSIGIPCNNIQKDFYKFPQGSHLIFYKLIDKNS
IHIIRILHKSVDVSAIIED

Download         Length: 300 bp

>T43770 NZ_AP027363:3321793-3322092 [Thalassotalea agarivorans]
GTGAACCTATTTCTACTGTCGAATAAGGCAAAAAATGACCTGGGAAATATAGCTTTGTTCAGTTATCACCGCTGGGGAAA
AGAGCAAAGAAACATATATATCAGACAATTCGATGAAGCTTTTGGGTTACTCGCCAAAAACCCTTCTATCGGTATCCCAT
GTAATAACATTCAAAAAGATTTCTACAAATTCCCACAAGGCAGCCACTTAATTTTCTATAAGCTAATTGATAAAAATAGT
ATTCATATAATTAGGATATTGCACAAAAGCGTGGATGTTTCCGCAATCATTGAAGATTAA

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 8969.98 Da        Isoelectric Point: 4.2950

>AT43770 WP_093330862.1 NZ_AP027363:3321554-3321796 [Thalassotalea agarivorans]
MAKNTSITLGDHFDSFIANQIQSGRYGSASEVVRSALRLLESQETKLNSLRRMLVEGENSGIADYDLESFINELDDELKM

Download         Length: 243 bp

>AT43770 NZ_AP027363:3321554-3321796 [Thalassotalea agarivorans]
ATGGCTAAGAACACAAGTATTACACTAGGCGATCATTTTGACAGTTTTATTGCGAATCAAATTCAAAGTGGTAGATATGG
TTCAGCCAGTGAAGTCGTAAGATCGGCACTTCGTTTATTAGAATCTCAAGAAACAAAGCTCAATAGTTTGCGACGCATGT
TAGTTGAAGGTGAAAACAGTGGTATAGCTGACTACGATCTTGAGTCTTTTATCAATGAGCTGGATGACGAGTTGAAAATG
TGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References