Detailed information of TA system TA043769

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/ParE-Phd
• Location: 942550..943094
• Replicon: chromosome
• Accession: NZ_AP027363
• Organism: Thalassotalea agarivorans strain JCM 13379

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: QUD85_RS04425
• Protein ID: WP_093327247.1
• Coordinates: 942795..943094 (+)
• Length: 100 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: QUD85_RS04420
• Protein ID: WP_093327245.1
• Coordinates: 942550..942807 (+)
• Length: 86 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
QUD85_RS04395	938090..938644	+	555	WP_093327238.1	LysR family transcriptional regulator	-
QUD85_RS04400	939771..940358	+	588	WP_093327240.1	hypothetical protein	-
QUD85_RS04405	940548..940883	+	336	WP_093327241.1	zinc ribbon domain-containing protein YjdM	-
QUD85_RS04410	941092..941343	+	252	Protein_857	zinc ribbon domain-containing protein YjdM	-
QUD85_RS04415	941362..942078	+	717	WP_093327243.1	SIMPL domain-containing protein	-
QUD85_RS04420	942550..942807	+	258	WP_093327245.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin
QUD85_RS04425	942795..943094	+	300	WP_093327247.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
QUD85_RS04430	943564..943824	+	261	WP_093327248.1	OadG family transporter subunit	-
QUD85_RS04435	943841..945622	+	1782	WP_093327250.1	sodium-extruding oxaloacetate decarboxylase subunit alpha	-
QUD85_RS04440	945632..946765	+	1134	WP_093327251.1	sodium ion-translocating decarboxylase subunit beta	-
QUD85_RS04445	947034..947687	-	654	WP_093327253.1	pyridoxamine 5'-phosphate oxidase	-
QUD85_RS04450	947839..948018	-	180	WP_093327254.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (4-91)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (1-66)

Sequences

Toxin

Protein

• Length: 100 a.a.
• Molecular weight: 11477.48 Da
• Isoelectric Point: 7.1650

>T43769 WP_093327247.1 NZ_AP027363:942795-943094 [Thalassotalea agarivorans]
MAEVIWTQPALNDLNDIAEYIAVANLVAAKKLVQTVFSKIERLEEHPDSGKVPLEIPTLNYRELVIKPCRVFYKIDGNKV
FILHVMRQEQDLRRFLLIS

Nucleotide

• Length: 300 bp

>T43769 NZ_AP027363:942795-943094 [Thalassotalea agarivorans]
ATGGCTGAAGTAATTTGGACGCAACCCGCTCTAAATGACCTTAATGATATTGCTGAATACATTGCAGTGGCTAACTTGGT
TGCTGCGAAAAAGCTAGTTCAAACCGTATTTAGCAAAATCGAAAGGCTAGAAGAACACCCCGACTCGGGCAAAGTTCCTT
TGGAAATACCAACGCTTAATTATAGGGAGCTAGTAATCAAGCCATGTCGAGTTTTTTATAAAATTGACGGAAACAAGGTT
TTTATATTGCATGTCATGCGTCAAGAACAAGATCTTAGACGTTTCTTGCTAATTTCGTAA

Antitoxin

Protein

• Length: 86 a.a.
• Molecular weight: 9727.27 Da
• Isoelectric Point: 7.2038

>AT43769 WP_093327245.1 NZ_AP027363:942550-942807 [Thalassotalea agarivorans]
MKVELVTTLKRQATKILADLHSSKEPVLITEHGQPSAYLVDVDDFEMMQKRMSILEGIARGEQAIRDEQVVSSTRAKEQM
NKWLK

Nucleotide

• Length: 258 bp

>AT43769 NZ_AP027363:942550-942807 [Thalassotalea agarivorans]
ATGAAAGTTGAATTAGTTACTACCTTAAAGAGGCAAGCTACTAAAATATTAGCAGACCTCCATTCTTCTAAAGAACCGGT
TTTAATTACTGAGCATGGCCAACCGTCTGCATATTTGGTAGATGTTGACGACTTTGAAATGATGCAAAAGCGTATGTCGA
TTTTAGAAGGAATAGCTAGGGGGGAACAGGCGATTAGAGATGAGCAAGTTGTTTCAAGTACGCGTGCCAAAGAGCAAATG
AATAAATGGCTGAAGTAA