Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/Phd(antitoxin)
Location 3787876..3788420 Replicon chromosome
Accession NZ_AP027362
Organism Thalassotalea piscium strain JCM 18590

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag QUD79_RS16905 Protein ID WP_184423419.1
Coordinates 3787876..3788175 (-) Length 100 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag QUD79_RS16910 Protein ID WP_184423420.1
Coordinates 3788163..3788420 (-) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QUD79_RS16875 3782962..3783456 - 495 WP_184423411.1 hypothetical protein -
QUD79_RS16880 3783571..3785115 - 1545 Protein_3290 glutamate synthase-related protein -
QUD79_RS16885 3785286..3785633 - 348 WP_184423413.1 lactoylglutathione lyase -
QUD79_RS16890 3785821..3786264 - 444 WP_184423415.1 hypothetical protein -
QUD79_RS16895 3786290..3786733 - 444 WP_184423416.1 hypothetical protein -
QUD79_RS16900 3787312..3787707 - 396 WP_184423418.1 ACT domain-containing protein -
QUD79_RS16905 3787876..3788175 - 300 WP_184423419.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
QUD79_RS16910 3788163..3788420 - 258 WP_184423420.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
QUD79_RS16915 3788924..3789208 + 285 WP_184423421.1 damage-inducible protein J -
QUD79_RS16920 3789709..3790683 - 975 WP_184423422.1 transposase -
QUD79_RS16925 3790929..3791426 - 498 WP_184423423.1 DUF2867 domain-containing protein -
QUD79_RS16930 3791679..3792641 + 963 WP_184423424.1 integron integrase -
QUD79_RS16935 3792683..3793375 - 693 WP_184423425.1 NAD(P)H-flavin reductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-87)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-67)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11715.56 Da        Isoelectric Point: 8.8168

>T43768 WP_184423419.1 NZ_AP027362:c3788175-3787876 [Thalassotalea piscium]
MAEVIWASTALDDLYEIAEYIALSNFPAAKKLTQKIFDKISRLENHPESGKRPLELVSLNYREVNVNPCRIFYKVDNDKV
YILHVMRQERDLRRYLLKS

Download         Length: 300 bp

>T43768 NZ_AP027362:c3788175-3787876 [Thalassotalea piscium]
ATGGCTGAAGTAATATGGGCATCTACAGCCCTTGATGATTTATACGAGATCGCTGAATACATTGCCTTAAGTAACTTTCC
TGCTGCAAAGAAGTTGACTCAAAAAATATTTGATAAAATATCTAGGTTAGAAAATCATCCAGAGTCAGGTAAAAGGCCGC
TAGAATTGGTGAGCTTAAATTACCGTGAAGTAAATGTTAATCCTTGTCGTATTTTTTATAAAGTGGATAACGACAAAGTG
TACATTTTACATGTTATGCGTCAAGAGCGAGATTTACGCAGGTATCTTTTAAAAAGTTAA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9846.38 Da        Isoelectric Point: 7.2032

>AT43768 WP_184423420.1 NZ_AP027362:c3788420-3788163 [Thalassotalea piscium]
MRVELVTTLKRQATKILADLHTSKEPVLITEHGQPSAYLVDVEDYEFMQQRMAILERVARGEQAIKNGEIFSNQEAKEKM
SKWLK

Download         Length: 258 bp

>AT43768 NZ_AP027362:c3788420-3788163 [Thalassotalea piscium]
ATGAGAGTTGAACTTGTAACAACACTTAAACGGCAAGCTACTAAAATTCTAGCAGACTTACATACATCAAAAGAACCTGT
ACTAATTACTGAACACGGTCAACCATCTGCTTACTTAGTTGACGTGGAAGATTATGAGTTTATGCAACAGCGAATGGCAA
TTCTTGAGCGTGTTGCACGCGGTGAGCAAGCAATTAAAAATGGTGAAATATTCTCAAATCAGGAAGCAAAAGAGAAAATG
AGTAAATGGCTGAAGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References