Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) parDE/ParE-RHH
Location 1096784..1097316 Replicon chromosome
Accession NZ_AP027362
Organism Thalassotalea piscium strain JCM 18590

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag QUD79_RS04630 Protein ID WP_184423763.1
Coordinates 1097023..1097316 (+) Length 98 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag QUD79_RS04625 Protein ID WP_184423764.1
Coordinates 1096784..1097023 (+) Length 80 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QUD79_RS04605 1093230..1094363 + 1134 WP_184423768.1 sodium ion-translocating decarboxylase subunit beta -
QUD79_RS04610 1094463..1095203 - 741 WP_184423767.1 hypothetical protein -
QUD79_RS04615 1095303..1095956 - 654 WP_184423766.1 pyridoxamine 5'-phosphate oxidase -
QUD79_RS04620 1096133..1096336 - 204 WP_184423765.1 hypothetical protein -
QUD79_RS04625 1096784..1097023 + 240 WP_184423764.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
QUD79_RS04630 1097023..1097316 + 294 WP_184423763.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
QUD79_RS04635 1097652..1098920 + 1269 WP_184423762.1 IS110 family transposase -
QUD79_RS04640 1098954..1099538 - 585 WP_184423761.1 hypothetical protein -
QUD79_RS04645 1100162..1101457 - 1296 WP_184423760.1 amidohydrolase -
QUD79_RS04650 1101720..1101929 - 210 WP_286290048.1 hypothetical protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(5-92)

Antitoxin

(4-70)


Sequences


Toxin        


Download         Length: 98 a.a.        Molecular weight: 11261.07 Da        Isoelectric Point: 9.2613

>T43766 WP_184423763.1 NZ_AP027362:1097023-1097316 [Thalassotalea piscium]
MEKLVLSAKAKSDLIKIARYTQLTWGTTQRNDYLKILDSTFRLLAEEPELGINCDYIKEGYSKYPQASHVIYYKEHKVNQ
ILIVRVLHKSMDVNSAI

Download         Length: 294 bp

>T43766 NZ_AP027362:1097023-1097316 [Thalassotalea piscium]
ATGGAAAAATTAGTATTATCCGCTAAAGCGAAATCAGACTTAATTAAAATAGCTCGATACACTCAACTTACATGGGGAAC
CACGCAACGAAATGATTATTTAAAAATATTAGATAGCACATTTCGATTATTAGCTGAGGAGCCAGAGTTAGGAATAAACT
GTGATTACATCAAAGAGGGTTACAGTAAATATCCTCAAGCTAGCCACGTAATTTATTACAAAGAACATAAAGTTAATCAA
ATATTAATTGTACGTGTGCTGCATAAAAGTATGGATGTTAACTCTGCTATCTAG

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 8887.82 Da        Isoelectric Point: 4.5007

>AT43766 WP_184423764.1 NZ_AP027362:1096784-1097023 [Thalassotalea piscium]
MAKNTSVTLGDHFDQFINQQLKTGRYGSASEIVRAGLRALEDQETKLLNLRNMLIQGEQSGIADYSYDSLLTELDNENH

Download         Length: 240 bp

>AT43766 NZ_AP027362:1096784-1097023 [Thalassotalea piscium]
ATGGCTAAAAATACAAGCGTTACACTAGGCGATCATTTTGATCAGTTTATAAACCAACAACTTAAAACTGGACGTTATGG
CTCAGCAAGTGAAATTGTTAGAGCTGGATTAAGAGCTTTAGAAGATCAAGAAACTAAACTATTAAATTTACGCAATATGC
TTATTCAAGGCGAACAAAGCGGTATAGCTGATTACAGTTATGATTCTTTATTAACAGAATTAGATAACGAAAATCACTAA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References