Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 3258214..3258773 Replicon chromosome
Accession NZ_AP027292
Organism Neptuniibacter halophilus strain LMG 25378

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag QUD59_RS15250 Protein ID WP_286238020.1
Coordinates 3258214..3258492 (-) Length 93 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag QUD59_RS15255 Protein ID WP_286238021.1
Coordinates 3258492..3258773 (-) Length 94 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QUD59_RS15225 3254005..3255141 + 1137 WP_286238012.1 4-phosphoerythronate dehydrogenase PdxB -
QUD59_RS15230 3255191..3255898 + 708 WP_286238014.1 flagellar brake protein -
QUD59_RS15235 3255891..3257003 + 1113 WP_286238015.1 ATP-NAD kinase family protein -
QUD59_RS15240 3257053..3257304 + 252 WP_286238016.1 hypothetical protein -
QUD59_RS15245 3257373..3257936 + 564 WP_286238017.1 hypothetical protein -
QUD59_RS15250 3258214..3258492 - 279 WP_286238020.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
QUD59_RS15255 3258492..3258773 - 282 WP_286238021.1 damage-inducible protein J Antitoxin
QUD59_RS15260 3258922..3259638 - 717 WP_286238022.1 YebC/PmpR family DNA-binding transcriptional regulator -
QUD59_RS15265 3259862..3261634 - 1773 WP_286238023.1 acyl-CoA dehydrogenase -
QUD59_RS15270 3261771..3262703 - 933 WP_286238024.1 FAD-binding protein -
QUD59_RS15275 3262712..3263461 - 750 WP_286238026.1 electron transfer flavoprotein subunit beta/FixA family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(1-89)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 93 a.a.        Molecular weight: 10782.54 Da        Isoelectric Point: 4.4791

>T43692 WP_286238020.1 NZ_AP027292:c3258492-3258214 [Neptuniibacter halophilus]
MILWEEASLNDREKIFEFLYDFNPDAAERTDQLIELKVENLLLQTLMGVQREGIPGRLLIIPEISMIVSYWVDGGNIHVM
RVLHQKQKFPLD

Download         Length: 279 bp

>T43692 NZ_AP027292:c3258492-3258214 [Neptuniibacter halophilus]
ATGATTTTATGGGAGGAAGCATCGCTTAACGACCGGGAAAAGATTTTTGAATTTCTCTACGATTTCAATCCCGACGCAGC
AGAAAGAACAGACCAACTGATTGAGTTAAAAGTAGAAAATCTGCTTCTGCAAACATTGATGGGCGTGCAGAGAGAAGGAA
TTCCGGGGCGACTACTGATCATCCCTGAAATTTCAATGATCGTATCTTACTGGGTTGACGGTGGTAACATCCACGTCATG
CGAGTACTCCACCAAAAGCAAAAATTTCCTCTCGACTGA

Antitoxin


Download         Length: 94 a.a.        Molecular weight: 10777.02 Da        Isoelectric Point: 8.0550

>AT43692 WP_286238021.1 NZ_AP027292:c3258773-3258492 [Neptuniibacter halophilus]
MDTRIQFRVNEETKRLAQQMAESQGRTLSDACRELTEQLAEQQRKALSHDAWLTEQINQAFKALDAGETTFVDHESAKAQ
MEARKARIRNRSR

Download         Length: 282 bp

>AT43692 NZ_AP027292:c3258773-3258492 [Neptuniibacter halophilus]
ATGGACACCCGAATCCAGTTCCGTGTAAATGAAGAAACCAAGCGACTGGCTCAGCAGATGGCGGAAAGTCAGGGTCGAAC
TCTGAGTGATGCCTGCCGCGAACTGACCGAGCAACTGGCAGAACAACAGCGAAAAGCACTGTCTCATGACGCCTGGTTAA
CTGAGCAGATAAACCAGGCTTTCAAAGCGCTGGATGCCGGAGAGACAACCTTTGTCGACCATGAATCTGCAAAAGCTCAA
ATGGAGGCACGCAAAGCCAGAATCCGTAACCGGAGCAGGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References