Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pemIK/PRK09812-ChpS
Location 242637..243217 Replicon chromosome
Accession NZ_AP027204
Organism Polynucleobacter sp. SHI8

Toxin (Protein)


Gene name pemK Uniprot ID -
Locus tag QMN06_RS01300 Protein ID WP_281970695.1
Coordinates 242891..243217 (+) Length 109 a.a.

Antitoxin (Protein)


Gene name pemI Uniprot ID -
Locus tag QMN06_RS01295 Protein ID WP_281970694.1
Coordinates 242637..242891 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QMN06_RS01270 (PSHI8_02410) 237776..239779 + 2004 WP_281970689.1 transketolase -
QMN06_RS01275 (PSHI8_02420) 239837..240847 + 1011 WP_281970690.1 type I glyceraldehyde-3-phosphate dehydrogenase -
QMN06_RS01280 (PSHI8_02430) 240991..241188 - 198 WP_281970691.1 type II toxin-antitoxin system VapB family antitoxin -
QMN06_RS01285 (PSHI8_02440) 241392..241592 + 201 WP_281970692.1 CopG family transcriptional regulator -
QMN06_RS01290 (PSHI8_02460) 241971..242357 + 387 WP_281970693.1 hypothetical protein -
QMN06_RS01295 (PSHI8_02470) 242637..242891 + 255 WP_281970694.1 antitoxin Antitoxin
QMN06_RS01300 (PSHI8_02480) 242891..243217 + 327 WP_281970695.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
QMN06_RS01305 (PSHI8_02490) 243282..243728 - 447 WP_281970696.1 ferric iron uptake transcriptional regulator -
QMN06_RS01310 (PSHI8_02500) 243837..244421 + 585 WP_281970697.1 outer membrane protein assembly factor BamE -
QMN06_RS01315 (PSHI8_02510) 244438..245253 + 816 WP_281970698.1 4-hydroxy-tetrahydrodipicolinate reductase -
QMN06_RS01320 (PSHI8_02520) 245284..247908 + 2625 WP_281970699.1 leucine--tRNA ligase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(1-107)

Antitoxin

Antitoxin PemI-like

(1-84)


Sequences

Toxin        


Download         Length: 109 a.a.        Molecular weight: 11453.36 Da        Isoelectric Point: 10.2073

>T43478 WP_281970695.1 NZ_AP027204:242891-243217 [Polynucleobacter sp. SHI8]
MNRGDIYLVSLDPTSGHEQRGVRPVLVVSSGPFNKLTKAPIVVPITTGGNFARVAGFTVDLVGSKTVGVVRCDQPRVLDL
AARKAKKLESVQADVIDEVLAKLATLIS

Download         Length: 327 bp

>T43478 NZ_AP027204:242891-243217 [Polynucleobacter sp. SHI8]
ATGAATCGTGGCGATATTTATTTGGTATCATTGGATCCGACCTCTGGACATGAGCAAAGAGGGGTTCGACCAGTGCTAGT
GGTTTCTTCAGGGCCATTTAATAAACTAACTAAGGCACCGATTGTGGTACCAATCACAACAGGTGGAAACTTTGCCCGAG
TTGCTGGATTTACAGTCGATTTAGTTGGTTCAAAAACAGTAGGTGTTGTCCGATGTGATCAGCCTAGAGTGTTAGACTTG
GCTGCGCGCAAAGCAAAGAAGTTAGAGAGTGTTCAGGCGGATGTAATAGATGAGGTATTGGCTAAATTGGCTACATTGAT
TTCATAA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9319.09 Da        Isoelectric Point: 7.9734

>AT43478 WP_281970694.1 NZ_AP027204:242637-242891 [Polynucleobacter sp. SHI8]
MQTNLRKVGGSVMLAVSPVFLEELKINSGSTVEVALLEGRLVVKPITKPKYKLEDLLAKCDPKAKMPKEDKEWLELTPVG
NEIL

Download         Length: 255 bp

>AT43478 NZ_AP027204:242637-242891 [Polynucleobacter sp. SHI8]
ATGCAAACAAATTTAAGGAAAGTCGGCGGTTCCGTCATGCTGGCAGTATCGCCAGTATTTTTAGAAGAGTTGAAAATTAA
TTCAGGATCGACGGTTGAGGTTGCCTTACTTGAGGGACGCTTAGTGGTAAAGCCTATAACCAAACCAAAATATAAATTAG
AGGATTTATTAGCAAAGTGTGATCCGAAAGCAAAAATGCCCAAAGAGGATAAGGAGTGGCTTGAGCTTACTCCAGTTGGC
AATGAGATCTTGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References