Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2554052..2554286 Replicon chromosome
Accession NZ_AP027197
Organism Escherichia coli strain 02E060

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2554053..2554156 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2554052..2554286 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QMG97_RS13485 2549984..2550388 + 405 Protein_2647 recombinase RecT -
QMG97_RS13490 2550453..2551609 + 1157 WP_085948186.1 IS3-like element IS600 family transposase -
QMG97_RS13495 2551653..2552060 + 408 Protein_2649 recombinase RecT -
QMG97_RS13500 2552117..2552311 + 195 WP_042853000.1 type I toxin-antitoxin system endodeoxyribonuclease toxin RalR -
QMG97_RS13505 2552304..2552492 + 189 WP_001356607.1 DUF1187 family protein -
- 2552310..2552488 - 179 NuclAT_1 - -
- 2552310..2552488 - 179 NuclAT_1 - -
- 2552310..2552488 - 179 NuclAT_1 - -
- 2552310..2552488 - 179 NuclAT_1 - -
QMG97_RS13510 2552599..2552880 + 282 WP_001443927.1 excisionase -
QMG97_RS13515 2552846..2553961 + 1116 WP_001189092.1 phage integrase Arm DNA-binding domain-containing protein -
- 2554052..2554286 + 235 - - Antitoxin
- 2554053..2554156 - 104 - - Toxin
QMG97_RS13520 2554314..2554655 - 342 WP_000976492.1 YebY family protein -
QMG97_RS13525 2554668..2555540 - 873 WP_000879280.1 copper homeostasis membrane protein CopD -
QMG97_RS13530 2555544..2555918 - 375 WP_000204699.1 CopC domain-containing protein YobA -
QMG97_RS13535 2556057..2556287 + 231 WP_000916763.1 DNA polymerase III subunit theta -
QMG97_RS13540 2556389..2557045 + 657 WP_000011658.1 carbon-nitrogen hydrolase family protein YobB -
QMG97_RS13545 2557069..2557731 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - nleG7' 2495152..2559788 64636


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T43450 NZ_AP027197:c2554156-2554053 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT

Antitoxin


Download         Length: 235 bp

>AT43450 NZ_AP027197:2554052-2554286 [Escherichia coli]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References