Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 2680583..2680817 | Replicon | chromosome |
| Accession | NZ_AP027191 | ||
| Organism | Escherichia coli strain 10153 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 2680584..2680687 (-) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 2680583..2680817 (+) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| QMG89_RS14400 | 2677782..2678591 | + | 810 | WP_000166317.1 | recombination protein RecT | - |
| QMG89_RS14405 | 2678648..2678842 | + | 195 | WP_042853000.1 | type I toxin-antitoxin system endodeoxyribonuclease toxin RalR | - |
| QMG89_RS14410 | 2678835..2679023 | + | 189 | WP_001356607.1 | DUF1187 family protein | - |
| - | 2678841..2679019 | - | 179 | NuclAT_1 | - | - |
| - | 2678841..2679019 | - | 179 | NuclAT_1 | - | - |
| - | 2678841..2679019 | - | 179 | NuclAT_1 | - | - |
| - | 2678841..2679019 | - | 179 | NuclAT_1 | - | - |
| QMG89_RS14415 | 2679130..2679411 | + | 282 | WP_001443927.1 | excisionase | - |
| QMG89_RS14420 | 2679377..2680492 | + | 1116 | WP_001189092.1 | phage integrase Arm DNA-binding domain-containing protein | - |
| - | 2680583..2680817 | + | 235 | - | - | Antitoxin |
| - | 2680584..2680687 | - | 104 | - | - | Toxin |
| QMG89_RS14425 | 2680845..2681186 | - | 342 | WP_000976492.1 | YebY family protein | - |
| QMG89_RS14430 | 2681199..2682071 | - | 873 | WP_000879280.1 | copper homeostasis membrane protein CopD | - |
| QMG89_RS14435 | 2682075..2682449 | - | 375 | WP_000204699.1 | CopC domain-containing protein YobA | - |
| QMG89_RS14440 | 2682588..2682818 | + | 231 | WP_000916763.1 | DNA polymerase III subunit theta | - |
| QMG89_RS14445 | 2682920..2683576 | + | 657 | WP_000011658.1 | carbon-nitrogen hydrolase family protein YobB | - |
| QMG89_RS14450 | 2683600..2684262 | + | 663 | WP_000944256.1 | exodeoxyribonuclease X | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | nleG7' | 2615342..2709716 | 94374 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 104 bp
>T43409 NZ_AP027191:c2680687-2680584 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
Antitoxin
Download Length: 235 bp
>AT43409 NZ_AP027191:2680583-2680817 [Escherichia coli]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
