Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 2643461..2643695 | Replicon | chromosome |
| Accession | NZ_AP027188 | ||
| Organism | Escherichia coli strain PV0838 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 2643462..2643565 (-) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 2643461..2643695 (+) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| QMG68_RS14145 | 2640660..2641469 | + | 810 | WP_000166317.1 | recombination protein RecT | - |
| QMG68_RS14150 | 2641526..2641720 | + | 195 | WP_042853000.1 | type I toxin-antitoxin system endodeoxyribonuclease toxin RalR | - |
| QMG68_RS14155 | 2641713..2641901 | + | 189 | WP_001356607.1 | DUF1187 family protein | - |
| - | 2641719..2641897 | - | 179 | NuclAT_0 | - | - |
| - | 2641719..2641897 | - | 179 | NuclAT_0 | - | - |
| - | 2641719..2641897 | - | 179 | NuclAT_0 | - | - |
| - | 2641719..2641897 | - | 179 | NuclAT_0 | - | - |
| QMG68_RS14160 | 2642008..2642289 | + | 282 | WP_001443927.1 | excisionase | - |
| QMG68_RS14165 | 2642255..2643370 | + | 1116 | WP_001189092.1 | phage integrase Arm DNA-binding domain-containing protein | - |
| - | 2643461..2643695 | + | 235 | - | - | Antitoxin |
| - | 2643462..2643565 | - | 104 | - | - | Toxin |
| QMG68_RS14170 | 2643723..2644064 | - | 342 | WP_000976492.1 | YebY family protein | - |
| QMG68_RS14175 | 2644077..2644949 | - | 873 | WP_000879280.1 | copper homeostasis membrane protein CopD | - |
| QMG68_RS14180 | 2644953..2645327 | - | 375 | WP_000204699.1 | CopC domain-containing protein YobA | - |
| QMG68_RS14185 | 2645466..2645696 | + | 231 | WP_000916763.1 | DNA polymerase III subunit theta | - |
| QMG68_RS14190 | 2645798..2646454 | + | 657 | WP_000011658.1 | carbon-nitrogen hydrolase family protein YobB | - |
| QMG68_RS14195 | 2646478..2647140 | + | 663 | WP_000944256.1 | exodeoxyribonuclease X | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | nleG7' | 2578220..2651105 | 72885 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 104 bp
>T43372 NZ_AP027188:c2643565-2643462 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
Antitoxin
Download Length: 235 bp
>AT43372 NZ_AP027188:2643461-2643695 [Escherichia coli]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
