Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 2577788..2578022 | Replicon | chromosome |
| Accession | NZ_AP027185 | ||
| Organism | Escherichia coli strain NIID080884 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 2577789..2577892 (-) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 2577788..2578022 (+) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| QMG74_RS13425 | 2574987..2575796 | + | 810 | WP_000166317.1 | recombination protein RecT | - |
| QMG74_RS13430 | 2575853..2576047 | + | 195 | WP_042853000.1 | type I toxin-antitoxin system endodeoxyribonuclease toxin RalR | - |
| QMG74_RS13435 | 2576040..2576228 | + | 189 | WP_001356607.1 | DUF1187 family protein | - |
| - | 2576046..2576224 | - | 179 | NuclAT_0 | - | - |
| - | 2576046..2576224 | - | 179 | NuclAT_0 | - | - |
| - | 2576046..2576224 | - | 179 | NuclAT_0 | - | - |
| - | 2576046..2576224 | - | 179 | NuclAT_0 | - | - |
| QMG74_RS13440 | 2576335..2576616 | + | 282 | WP_001443927.1 | excisionase | - |
| QMG74_RS13445 | 2576582..2577697 | + | 1116 | WP_001189092.1 | phage integrase Arm DNA-binding domain-containing protein | - |
| - | 2577788..2578022 | + | 235 | - | - | Antitoxin |
| - | 2577789..2577892 | - | 104 | - | - | Toxin |
| QMG74_RS13450 | 2578050..2578391 | - | 342 | WP_000976492.1 | YebY family protein | - |
| QMG74_RS13455 | 2578404..2579276 | - | 873 | WP_000879280.1 | copper homeostasis membrane protein CopD | - |
| QMG74_RS13460 | 2579280..2579654 | - | 375 | WP_000204699.1 | CopC domain-containing protein YobA | - |
| QMG74_RS13465 | 2579793..2580023 | + | 231 | WP_000916763.1 | DNA polymerase III subunit theta | - |
| QMG74_RS13470 | 2580125..2580781 | + | 657 | WP_000011658.1 | carbon-nitrogen hydrolase family protein YobB | - |
| QMG74_RS13475 | 2580805..2581467 | + | 663 | WP_000944256.1 | exodeoxyribonuclease X | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | nleG7' | 2512547..2618211 | 105664 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 104 bp
>T43337 NZ_AP027185:c2577892-2577789 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
Antitoxin
Download Length: 235 bp
>AT43337 NZ_AP027185:2577788-2578022 [Escherichia coli]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
