Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 2536453..2536687 | Replicon | chromosome |
| Accession | NZ_AP027181 | ||
| Organism | Escherichia coli strain 98E11 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 2536454..2536557 (-) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 2536453..2536687 (+) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| QMG82_RS13385 | 2533652..2534461 | + | 810 | WP_000166317.1 | recombination protein RecT | - |
| QMG82_RS13390 | 2534518..2534712 | + | 195 | WP_042853000.1 | type I toxin-antitoxin system endodeoxyribonuclease toxin RalR | - |
| QMG82_RS13395 | 2534705..2534893 | + | 189 | WP_001356607.1 | DUF1187 family protein | - |
| - | 2534711..2534889 | - | 179 | NuclAT_1 | - | - |
| - | 2534711..2534889 | - | 179 | NuclAT_1 | - | - |
| - | 2534711..2534889 | - | 179 | NuclAT_1 | - | - |
| - | 2534711..2534889 | - | 179 | NuclAT_1 | - | - |
| QMG82_RS13400 | 2535000..2535281 | + | 282 | WP_001443927.1 | excisionase | - |
| QMG82_RS13405 | 2535247..2536362 | + | 1116 | WP_001189092.1 | phage integrase Arm DNA-binding domain-containing protein | - |
| - | 2536453..2536687 | + | 235 | - | - | Antitoxin |
| - | 2536454..2536557 | - | 104 | - | - | Toxin |
| QMG82_RS13410 | 2536715..2537056 | - | 342 | WP_000976492.1 | YebY family protein | - |
| QMG82_RS13415 | 2537069..2537941 | - | 873 | WP_000879280.1 | copper homeostasis membrane protein CopD | - |
| QMG82_RS13420 | 2537945..2538319 | - | 375 | WP_000204699.1 | CopC domain-containing protein YobA | - |
| QMG82_RS13425 | 2538458..2538688 | + | 231 | WP_000916763.1 | DNA polymerase III subunit theta | - |
| QMG82_RS13430 | 2538790..2539446 | + | 657 | WP_000011658.1 | carbon-nitrogen hydrolase family protein YobB | - |
| QMG82_RS13435 | 2539470..2540132 | + | 663 | WP_000944256.1 | exodeoxyribonuclease X | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | nleG7' | 2469945..2544097 | 74152 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 104 bp
>T43303 NZ_AP027181:c2536557-2536454 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
Antitoxin
Download Length: 235 bp
>AT43303 NZ_AP027181:2536453-2536687 [Escherichia coli]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
