Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | paaR-paaA-parE/- |
Location | 1176599..1177077 | Replicon | chromosome |
Accession | NZ_AP027181 | ||
Organism | Escherichia coli strain 98E11 |
Toxin (Protein)
Gene name | parE_1 | Uniprot ID | A0A891SFN9 |
Locus tag | QMG82_RS05730 | Protein ID | WP_001303876.1 |
Coordinates | 1176599..1176886 (-) | Length | 96 a.a. |
Antitoxin (Protein)
Gene name | paaA | Uniprot ID | Q8XD67 |
Locus tag | QMG82_RS05735 | Protein ID | WP_000536233.1 |
Coordinates | 1176886..1177077 (-) | Length | 64 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
QMG82_RS05700 (1171822) | 1171822..1174272 | - | 2451 | WP_000048583.1 | exonuclease | - |
QMG82_RS05705 (1174366) | 1174366..1174557 | - | 192 | WP_001098307.1 | DUF1482 family protein | - |
QMG82_RS05710 (1174554) | 1174554..1174742 | - | 189 | WP_000413705.1 | cell division inhibition protein DicB | - |
QMG82_RS05715 (1175310) | 1175310..1175519 | + | 210 | WP_001133037.1 | hypothetical protein | - |
QMG82_RS05720 (1175520) | 1175520..1176158 | - | 639 | WP_000394543.1 | hypothetical protein | - |
QMG82_RS05725 (1176170) | 1176170..1176322 | - | 153 | WP_000380316.1 | DUF1391 family protein | - |
QMG82_RS05730 (1176599) | 1176599..1176886 | - | 288 | WP_001303876.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
QMG82_RS05735 (1176886) | 1176886..1177077 | - | 192 | WP_000536233.1 | hypothetical protein | Antitoxin |
QMG82_RS05740 (1177105) | 1177105..1177506 | - | 402 | WP_000986592.1 | helix-turn-helix domain-containing protein | - |
QMG82_RS05745 (1177615) | 1177615..1177887 | + | 273 | WP_000887453.1 | YdaS family helix-turn-helix protein | - |
QMG82_RS05750 (1177871) | 1177871..1178296 | + | 426 | WP_000693855.1 | toxin YdaT family protein | - |
QMG82_RS05755 (1178503) | 1178503..1178958 | - | 456 | WP_000273724.1 | hypothetical protein | - |
QMG82_RS05760 (1179037) | 1179037..1180152 | + | 1116 | WP_001205821.1 | hypothetical protein | - |
QMG82_RS05765 (1180159) | 1180159..1180905 | + | 747 | WP_000788742.1 | ATP-binding protein | - |
QMG82_RS05770 (1180927) | 1180927..1181697 | + | 771 | WP_000451007.1 | DUF1627 domain-containing protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 96 a.a. Molecular weight: 10978.84 Da Isoelectric Point: 10.1360
>T43291 WP_001303876.1 NZ_AP027181:c1176886-1176599 [Escherichia coli]
MLPILWLPSARDDLRQIITYIAKENPPAARRLKIRIETSVLPLSEHPYLYPPSERVSGLREIVTHPNYIILYRVAASSIE
IVSVTHSRRQFPFSI
MLPILWLPSARDDLRQIITYIAKENPPAARRLKIRIETSVLPLSEHPYLYPPSERVSGLREIVTHPNYIILYRVAASSIE
IVSVTHSRRQFPFSI
Download Length: 288 bp
>T43291 NZ_AP027181:c1176886-1176599 [Escherichia coli]
ATGTTACCCATTTTATGGCTACCGTCTGCTCGCGATGATTTGCGCCAGATCATAACTTACATCGCCAAGGAGAACCCACC
GGCAGCACGTAGACTAAAAATACGCATTGAAACATCGGTATTACCTCTATCTGAGCATCCGTACTTATATCCACCAAGCG
AACGGGTTTCTGGATTGAGAGAGATCGTGACCCACCCTAACTACATAATCCTGTACAGAGTAGCTGCTTCAAGCATTGAG
ATTGTAAGCGTGACACATTCTCGGCGACAATTTCCCTTCTCTATCTGA
ATGTTACCCATTTTATGGCTACCGTCTGCTCGCGATGATTTGCGCCAGATCATAACTTACATCGCCAAGGAGAACCCACC
GGCAGCACGTAGACTAAAAATACGCATTGAAACATCGGTATTACCTCTATCTGAGCATCCGTACTTATATCCACCAAGCG
AACGGGTTTCTGGATTGAGAGAGATCGTGACCCACCCTAACTACATAATCCTGTACAGAGTAGCTGCTTCAAGCATTGAG
ATTGTAAGCGTGACACATTCTCGGCGACAATTTCCCTTCTCTATCTGA
Antitoxin
Download Length: 64 a.a. Molecular weight: 7025.80 Da Isoelectric Point: 4.0270
>AT43291 WP_000536233.1 NZ_AP027181:c1177077-1176886 [Escherichia coli]
MGTALSPIVSEFETTEQENSYNEWLRTKVTSSLADTRPAIPHDEVMAEMENLIAQIAVTNKSE
MGTALSPIVSEFETTEQENSYNEWLRTKVTSSLADTRPAIPHDEVMAEMENLIAQIAVTNKSE
Download Length: 192 bp
>AT43291 NZ_AP027181:c1177077-1176886 [Escherichia coli]
ATGGGTACAGCCCTTTCTCCGATAGTTTCAGAATTCGAAACTACCGAACAAGAAAACAGTTACAACGAATGGTTGCGCAC
TAAAGTAACGTCAAGCCTTGCAGACACTCGCCCCGCAATTCCACATGACGAGGTAATGGCTGAAATGGAAAATCTTATTG
CTCAAATTGCTGTAACTAACAAGAGCGAGTAA
ATGGGTACAGCCCTTTCTCCGATAGTTTCAGAATTCGAAACTACCGAACAAGAAAACAGTTACAACGAATGGTTGCGCAC
TAAAGTAACGTCAAGCCTTGCAGACACTCGCCCCGCAATTCCACATGACGAGGTAATGGCTGAAATGGAAAATCTTATTG
CTCAAATTGCTGTAACTAACAAGAGCGAGTAA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|
Antitoxin
Source | ID | Structure |
---|