Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 2558915..2559149 | Replicon | chromosome |
| Accession | NZ_AP027176 | ||
| Organism | Escherichia coli strain EH2252 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 2558916..2559019 (-) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 2558915..2559149 (+) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| QMG71_RS13455 | 2556113..2556922 | + | 810 | WP_000166317.1 | recombination protein RecT | - |
| QMG71_RS13460 | 2556979..2557173 | + | 195 | WP_042853000.1 | type I toxin-antitoxin system endodeoxyribonuclease toxin RalR | - |
| QMG71_RS13465 | 2557166..2557354 | + | 189 | WP_001356607.1 | DUF1187 family protein | - |
| - | 2557172..2557350 | - | 179 | NuclAT_1 | - | - |
| - | 2557172..2557350 | - | 179 | NuclAT_1 | - | - |
| - | 2557172..2557350 | - | 179 | NuclAT_1 | - | - |
| - | 2557172..2557350 | - | 179 | NuclAT_1 | - | - |
| QMG71_RS13470 | 2557461..2557742 | + | 282 | WP_001443927.1 | excisionase | - |
| QMG71_RS13475 | 2557708..2558784 | + | 1077 | WP_001189091.1 | phage integrase Arm DNA-binding domain-containing protein | - |
| - | 2558915..2559149 | + | 235 | - | - | Antitoxin |
| - | 2558916..2559019 | - | 104 | - | - | Toxin |
| QMG71_RS13480 | 2559177..2559518 | - | 342 | WP_000976492.1 | YebY family protein | - |
| QMG71_RS13485 | 2559531..2560403 | - | 873 | WP_000879280.1 | copper homeostasis membrane protein CopD | - |
| QMG71_RS13490 | 2560407..2560781 | - | 375 | WP_000204699.1 | CopC domain-containing protein YobA | - |
| QMG71_RS13495 | 2560920..2561150 | + | 231 | WP_000916763.1 | DNA polymerase III subunit theta | - |
| QMG71_RS13500 | 2561252..2561908 | + | 657 | WP_000011658.1 | carbon-nitrogen hydrolase family protein YobB | - |
| QMG71_RS13505 | 2561932..2562594 | + | 663 | WP_000944256.1 | exodeoxyribonuclease X | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | nleG7' | 2501332..2564651 | 63319 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 104 bp
>T43259 NZ_AP027176:c2559019-2558916 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
Antitoxin
Download Length: 235 bp
>AT43259 NZ_AP027176:2558915-2559149 [Escherichia coli]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
