Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 2527325..2527559 | Replicon | chromosome |
| Accession | NZ_AP027170 | ||
| Organism | Escherichia coli strain 20.1 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 2527326..2527429 (-) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 2527325..2527559 (+) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| QMG87_RS13345 | 2522773..2524530 | + | 1758 | Protein_2623 | exodeoxyribonuclease VIII | - |
| QMG87_RS13350 | 2524523..2525332 | + | 810 | WP_000166317.1 | recombination protein RecT | - |
| QMG87_RS13355 | 2525389..2525583 | + | 195 | WP_042853000.1 | type I toxin-antitoxin system endodeoxyribonuclease toxin RalR | - |
| QMG87_RS13360 | 2525576..2525764 | + | 189 | WP_001356607.1 | DUF1187 family protein | - |
| - | 2525582..2525760 | - | 179 | NuclAT_1 | - | - |
| - | 2525582..2525760 | - | 179 | NuclAT_1 | - | - |
| - | 2525582..2525760 | - | 179 | NuclAT_1 | - | - |
| - | 2525582..2525760 | - | 179 | NuclAT_1 | - | - |
| QMG87_RS13365 | 2525871..2526152 | + | 282 | WP_001443927.1 | excisionase | - |
| QMG87_RS13370 | 2526118..2527194 | + | 1077 | WP_001189091.1 | phage integrase Arm DNA-binding domain-containing protein | - |
| - | 2527325..2527559 | + | 235 | - | - | Antitoxin |
| - | 2527326..2527429 | - | 104 | - | - | Toxin |
| QMG87_RS13375 | 2527587..2527928 | - | 342 | WP_000976492.1 | YebY family protein | - |
| QMG87_RS13380 | 2527941..2528813 | - | 873 | WP_000879280.1 | copper homeostasis membrane protein CopD | - |
| QMG87_RS13385 | 2528817..2529191 | - | 375 | WP_000204699.1 | CopC domain-containing protein YobA | - |
| QMG87_RS13390 | 2529330..2529560 | + | 231 | WP_000916763.1 | DNA polymerase III subunit theta | - |
| QMG87_RS13395 | 2529662..2530318 | + | 657 | WP_000011658.1 | carbon-nitrogen hydrolase family protein YobB | - |
| QMG87_RS13400 | 2530342..2531004 | + | 663 | WP_000944256.1 | exodeoxyribonuclease X | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | nleG7' | 2462139..2567749 | 105610 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 104 bp
>T43215 NZ_AP027170:c2527429-2527326 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
Antitoxin
Download Length: 235 bp
>AT43215 NZ_AP027170:2527325-2527559 [Escherichia coli]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
