Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 2417552..2417786 | Replicon | chromosome |
| Accession | NZ_AP027165 | ||
| Organism | Escherichia coli strain H19 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 2417553..2417656 (-) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 2417552..2417786 (+) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| QMG77_RS12565 | 2413000..2414757 | + | 1758 | Protein_2474 | exodeoxyribonuclease VIII | - |
| QMG77_RS12570 | 2414750..2415559 | + | 810 | WP_000166317.1 | recombination protein RecT | - |
| QMG77_RS12575 | 2415616..2415810 | + | 195 | WP_042853000.1 | type I toxin-antitoxin system endodeoxyribonuclease toxin RalR | - |
| QMG77_RS12580 | 2415803..2415991 | + | 189 | WP_001356607.1 | DUF1187 family protein | - |
| - | 2415809..2415987 | - | 179 | NuclAT_1 | - | - |
| - | 2415809..2415987 | - | 179 | NuclAT_1 | - | - |
| - | 2415809..2415987 | - | 179 | NuclAT_1 | - | - |
| - | 2415809..2415987 | - | 179 | NuclAT_1 | - | - |
| QMG77_RS12585 | 2416098..2416379 | + | 282 | WP_001443927.1 | excisionase | - |
| QMG77_RS12590 | 2416345..2417421 | + | 1077 | WP_001189091.1 | phage integrase Arm DNA-binding domain-containing protein | - |
| - | 2417552..2417786 | + | 235 | - | - | Antitoxin |
| - | 2417553..2417656 | - | 104 | - | - | Toxin |
| QMG77_RS12595 | 2417814..2418155 | - | 342 | WP_000976492.1 | YebY family protein | - |
| QMG77_RS12600 | 2418168..2419040 | - | 873 | WP_000879280.1 | copper homeostasis membrane protein CopD | - |
| QMG77_RS12605 | 2419044..2419418 | - | 375 | WP_000204699.1 | CopC domain-containing protein YobA | - |
| QMG77_RS12610 | 2419557..2419787 | + | 231 | WP_000916763.1 | DNA polymerase III subunit theta | - |
| QMG77_RS12615 | 2419889..2420545 | + | 657 | WP_000011658.1 | carbon-nitrogen hydrolase family protein YobB | - |
| QMG77_RS12620 | 2420569..2421231 | + | 663 | WP_000944256.1 | exodeoxyribonuclease X | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | nleG7' | 2359974..2423288 | 63314 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 104 bp
>T43174 NZ_AP027165:c2417656-2417553 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
Antitoxin
Download Length: 235 bp
>AT43174 NZ_AP027165:2417552-2417786 [Escherichia coli]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
