Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 2610962..2611196 | Replicon | chromosome |
| Accession | NZ_AP027162 | ||
| Organism | Escherichia coli strain EH031 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 2610963..2611066 (-) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 2610962..2611196 (+) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| QMG85_RS13740 | 2608159..2608969 | + | 811 | Protein_2704 | recombination protein RecT | - |
| QMG85_RS13745 | 2609026..2609220 | + | 195 | WP_042853000.1 | type I toxin-antitoxin system endodeoxyribonuclease toxin RalR | - |
| QMG85_RS13750 | 2609213..2609401 | + | 189 | WP_001356607.1 | DUF1187 family protein | - |
| - | 2609219..2609397 | - | 179 | NuclAT_1 | - | - |
| - | 2609219..2609397 | - | 179 | NuclAT_1 | - | - |
| - | 2609219..2609397 | - | 179 | NuclAT_1 | - | - |
| - | 2609219..2609397 | - | 179 | NuclAT_1 | - | - |
| QMG85_RS13755 | 2609508..2609789 | + | 282 | WP_001443927.1 | excisionase | - |
| QMG85_RS13760 | 2609755..2610831 | + | 1077 | WP_001189091.1 | phage integrase Arm DNA-binding domain-containing protein | - |
| - | 2610962..2611196 | + | 235 | - | - | Antitoxin |
| - | 2610963..2611066 | - | 104 | - | - | Toxin |
| QMG85_RS13765 | 2611224..2611565 | - | 342 | WP_000976492.1 | YebY family protein | - |
| QMG85_RS13770 | 2611578..2612450 | - | 873 | WP_000879280.1 | copper homeostasis membrane protein CopD | - |
| QMG85_RS13775 | 2612454..2612828 | - | 375 | WP_000204699.1 | CopC domain-containing protein YobA | - |
| QMG85_RS13780 | 2612967..2613197 | + | 231 | WP_000916763.1 | DNA polymerase III subunit theta | - |
| QMG85_RS13785 | 2613299..2613955 | + | 657 | WP_000011658.1 | carbon-nitrogen hydrolase family protein YobB | - |
| QMG85_RS13790 | 2613979..2614641 | + | 663 | WP_000944256.1 | exodeoxyribonuclease X | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | nleG7' | 2555895..2616698 | 60803 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 104 bp
>T43138 NZ_AP027162:c2611066-2610963 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
Antitoxin
Download Length: 235 bp
>AT43138 NZ_AP027162:2610962-2611196 [Escherichia coli]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
