Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/upstrm_HI1419-dnstrm_HI1420
Location 4363633..4364234 Replicon chromosome
Accession NZ_AP027149
Organism Methylocystis bryophila strain DSM 21852

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag QMG80_RS20225 Protein ID WP_245300099.1
Coordinates 4363633..4363902 (+) Length 90 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag QMG80_RS20230 Protein ID WP_085770810.1
Coordinates 4363899..4364234 (+) Length 112 a.a.

Genomic Context

QMG80_RS20210QMG80_RS20215QMG80_RS20220QMG80_RS20225QMG80_RS20230QMG80_RS20240QMG80_RS20245QMG80_RS20250QMG80_RS20205QMG80_RS20235QMG80_RS20255QMG80_RS20260
Location: 4360272..4360535 (264 bp)
Type: Others
Protein ID: WP_199769037.1
Location: 4360532..4360912 (381 bp)
Type: Others
Protein ID: WP_158658624.1
Location: 4361018..4362718 (1701 bp)
Type: Others
Protein ID: WP_085770808.1
Location: 4363633..4363902 (270 bp)
Type: Toxin
Protein ID: WP_245300099.1
Location: 4363899..4364234 (336 bp)
Type: Antitoxin
Protein ID: WP_085770810.1
Location: 4365744..4366016 (273 bp)
Type: Others
Protein ID: WP_085773551.1
Location: 4366013..4366300 (288 bp)
Type: Others
Protein ID: WP_085770811.1
Location: 4366565..4366759 (195 bp)
Type: Others
Protein ID: WP_085770812.1
Location: 4358978..4360114 (1137 bp)
Type: Others
Protein ID: WP_085773548.1
Location: 4364295..4365599 (1305 bp)
Type: Others
Protein ID: WP_085773550.1
Location: 4366783..4367643 (861 bp)
Type: Others
Protein ID: WP_085770813.1
Location: 4368063..4368404 (342 bp)
Type: Others
Protein ID: WP_085770815.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
QMG80_RS20205 (DSM21852_40540)4358978..4360114-1137WP_085773548.1alanine racemase-
QMG80_RS20210 (DSM21852_40550)4360272..4360535+264WP_199769037.1type II toxin-antitoxin system ParD family antitoxin-
QMG80_RS20215 (DSM21852_40560)4360532..4360912+381WP_158658624.1type II toxin-antitoxin system RelE/ParE family toxin-
QMG80_RS20220 (DSM21852_40570)4361018..4362718+1701WP_085770808.1lysine--tRNA ligase-
QMG80_RS202254363633..4363902+270WP_245300099.1type II toxin-antitoxin system RelE/ParE family toxinToxin
QMG80_RS20230 (DSM21852_40600)4363899..4364234+336WP_085770810.1putative addiction module antidote proteinAntitoxin
QMG80_RS20235 (DSM21852_40610)4364295..4365599-1305WP_085773550.1dihydroorotase-
QMG80_RS20240 (DSM21852_40620)4365744..4366016+273WP_085773551.1type II toxin-antitoxin system ParD family antitoxin-
QMG80_RS20245 (DSM21852_40630)4366013..4366300+288WP_085770811.1type II toxin-antitoxin system RelE/ParE family toxin-
QMG80_RS20250 (DSM21852_40640)4366565..4366759+195WP_085770812.1hypothetical protein-
QMG80_RS20255 (DSM21852_40650)4366783..4367643-861WP_085770813.1enoyl-ACP reductase FabI-
QMG80_RS20260 (DSM21852_40660)4368063..4368404-342WP_085770815.1hypothetical protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(9-84)

Antitoxin

Uncharacterized protein HI1420

(5-91)


Sequences

Toxin        


Download         Length: 90 a.a.        Molecular weight: 9846.43 Da        Isoelectric Point: 10.1390

>T43043 WP_245300099.1 NZ_AP027149:4363633-4363902 [Methylocystis bryophila]
VAVLSPGPQGKARILARLRSATFGNFGDCASVGEGVFEMRLHFGPGYRVYYVRAEKPIYLLLIGGDKSTQKMDIVRAKEM
ARAIEETNR

Download         Length: 270 bp

>T43043 NZ_AP027149:4363633-4363902 [Methylocystis bryophila]
GTGGCTGTCCTCTCTCCTGGACCACAAGGGAAGGCCAGAATTCTGGCGCGCTTGCGAAGCGCCACGTTCGGCAATTTCGG
CGATTGCGCTTCGGTGGGGGAAGGCGTTTTCGAAATGCGCCTCCACTTTGGACCCGGCTACCGTGTCTATTATGTGCGTG
CGGAGAAACCGATCTATCTCCTGCTGATCGGAGGCGACAAATCCACGCAAAAGATGGACATAGTCCGCGCCAAAGAGATG
GCGCGAGCGATCGAGGAGACGAATCGATGA

Antitoxin


Download         Length: 112 a.a.        Molecular weight: 11346.67 Da        Isoelectric Point: 4.4141

>AT43043 WP_085770810.1 NZ_AP027149:4363899-4364234 [Methylocystis bryophila]
MTTTFAPFDAADYLDSDATIAEYLTAAAEDPNSDVFLAALGDVAKARGMARIAKDTGLGRESLYKALSAGAHPRFETVNA
VLQALGVKIAIVPAGPGQDDSPAAGAADRHA

Download         Length: 336 bp

>AT43043 NZ_AP027149:4363899-4364234 [Methylocystis bryophila]
ATGACGACCACCTTTGCCCCCTTCGACGCCGCGGATTATCTCGATAGCGACGCGACGATCGCCGAATATCTCACAGCCGC
CGCCGAGGACCCAAACAGCGATGTCTTCCTCGCCGCGCTCGGCGACGTCGCCAAAGCGCGCGGCATGGCCCGGATCGCCA
AGGACACCGGCCTCGGCCGAGAAAGCCTTTACAAGGCGCTCAGCGCCGGCGCCCATCCGCGCTTTGAAACCGTGAATGCG
GTTTTGCAGGCTCTCGGTGTGAAAATCGCGATCGTCCCCGCGGGACCCGGACAGGACGACTCGCCGGCTGCCGGCGCGGC
AGACCGCCACGCATGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References