Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | vapBC/VapC-VagC |
| Location | 4023294..4023997 | Replicon | chromosome |
| Accession | NZ_AP027149 | ||
| Organism | Methylocystis bryophila strain DSM 21852 | ||
Toxin (Protein)
| Gene name | vapC | Uniprot ID | - |
| Locus tag | QMG80_RS18555 | Protein ID | WP_085770515.1 |
| Coordinates | 4023590..4023997 (+) | Length | 136 a.a. |
Antitoxin (Protein)
| Gene name | vapB | Uniprot ID | - |
| Locus tag | QMG80_RS18550 | Protein ID | WP_085770514.1 |
| Coordinates | 4023294..4023581 (+) | Length | 96 a.a. |
Genomic Context
Location: 4018610..4018798 (189 bp)
Type: Others
Protein ID: Protein_3651
Type: Others
Protein ID: Protein_3651
Location: 4018887..4020128 (1242 bp)
Type: Others
Protein ID: WP_085770510.1
Type: Others
Protein ID: WP_085770510.1
Location: 4020132..4020254 (123 bp)
Type: Others
Protein ID: WP_280950007.1
Type: Others
Protein ID: WP_280950007.1
Location: 4020296..4020943 (648 bp)
Type: Others
Protein ID: Protein_3654
Type: Others
Protein ID: Protein_3654
Location: 4021237..4022166 (930 bp)
Type: Others
Protein ID: WP_085770511.1
Type: Others
Protein ID: WP_085770511.1
Location: 4023294..4023581 (288 bp)
Type: Antitoxin
Protein ID: WP_085770514.1
Type: Antitoxin
Protein ID: WP_085770514.1
Location: 4023590..4023997 (408 bp)
Type: Toxin
Protein ID: WP_085770515.1
Type: Toxin
Protein ID: WP_085770515.1
Location: 4022661..4023014 (354 bp)
Type: Others
Protein ID: WP_085770513.1
Type: Others
Protein ID: WP_085770513.1
Location: 4024107..4025714 (1608 bp)
Type: Others
Protein ID: WP_085770516.1
Type: Others
Protein ID: WP_085770516.1
Location: 4025711..4026910 (1200 bp)
Type: Others
Protein ID: WP_085770517.1
Type: Others
Protein ID: WP_085770517.1
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Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| QMG80_RS18520 (DSM21852_37150) | 4018610..4018798 | + | 189 | Protein_3651 | LLM class flavin-dependent oxidoreductase | - |
| QMG80_RS18525 (DSM21852_37160) | 4018887..4020128 | + | 1242 | WP_085770510.1 | SfnB family sulfur acquisition oxidoreductase | - |
| QMG80_RS18530 | 4020132..4020254 | + | 123 | WP_280950007.1 | hypothetical protein | - |
| QMG80_RS18535 | 4020296..4020943 | + | 648 | Protein_3654 | LysR substrate-binding domain-containing protein | - |
| QMG80_RS18540 (DSM21852_37190) | 4021237..4022166 | + | 930 | WP_085770511.1 | MBL fold metallo-hydrolase | - |
| QMG80_RS18545 (DSM21852_37200) | 4022661..4023014 | - | 354 | WP_085770513.1 | DsrE family protein | - |
| QMG80_RS18550 (DSM21852_37210) | 4023294..4023581 | + | 288 | WP_085770514.1 | AbrB/MazE/SpoVT family DNA-binding domain-containing protein | Antitoxin |
| QMG80_RS18555 (DSM21852_37220) | 4023590..4023997 | + | 408 | WP_085770515.1 | PIN domain-containing protein | Toxin |
| QMG80_RS18560 (DSM21852_37230) | 4024107..4025714 | - | 1608 | WP_085770516.1 | efflux transporter outer membrane subunit | - |
| QMG80_RS18565 (DSM21852_37240) | 4025711..4026910 | - | 1200 | WP_085770517.1 | efflux RND transporter periplasmic adaptor subunit | - |
Associated MGEs
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MGE detail | Similar MGEs | Relative position | MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| No matching records found | |||||||
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 136 a.a. Molecular weight: 14918.15 Da Isoelectric Point: 6.3580
>T43042 WP_085770515.1 NZ_AP027149:4023590-4023997 [Methylocystis bryophila]
MFCLDTNIVIFALNKRRPWIATRLDNELRAGTALIVPAIVLFELNYGIAKSDRADQARALLDGFLSAGIGQPAFDAEDAR
EAADIRAFLERQGTPIGPFDYLVAAQARRRGAALVTLNRREFERVPGLMVTDWAA
MFCLDTNIVIFALNKRRPWIATRLDNELRAGTALIVPAIVLFELNYGIAKSDRADQARALLDGFLSAGIGQPAFDAEDAR
EAADIRAFLERQGTPIGPFDYLVAAQARRRGAALVTLNRREFERVPGLMVTDWAA
Download Length: 408 bp
>T43042 NZ_AP027149:4023590-4023997 [Methylocystis bryophila]
ATGTTTTGTCTCGACACGAACATCGTCATCTTCGCCTTGAACAAGCGGAGGCCCTGGATCGCCACGAGGCTCGATAATGA
GCTGAGGGCGGGAACGGCGCTCATCGTCCCCGCGATCGTGCTGTTCGAGCTCAACTACGGAATCGCCAAGAGCGACCGAG
CCGATCAAGCGCGCGCCCTGCTCGATGGCTTCTTGTCCGCCGGGATAGGCCAGCCGGCCTTCGACGCGGAGGATGCGCGC
GAGGCCGCGGACATAAGGGCGTTCCTCGAACGGCAAGGGACGCCGATCGGCCCCTTCGACTATCTCGTCGCGGCGCAGGC
GCGGCGGCGCGGCGCGGCGCTGGTGACGCTCAACCGCCGCGAGTTCGAGCGCGTGCCCGGCCTGATGGTGACGGATTGGG
CGGCATGA
ATGTTTTGTCTCGACACGAACATCGTCATCTTCGCCTTGAACAAGCGGAGGCCCTGGATCGCCACGAGGCTCGATAATGA
GCTGAGGGCGGGAACGGCGCTCATCGTCCCCGCGATCGTGCTGTTCGAGCTCAACTACGGAATCGCCAAGAGCGACCGAG
CCGATCAAGCGCGCGCCCTGCTCGATGGCTTCTTGTCCGCCGGGATAGGCCAGCCGGCCTTCGACGCGGAGGATGCGCGC
GAGGCCGCGGACATAAGGGCGTTCCTCGAACGGCAAGGGACGCCGATCGGCCCCTTCGACTATCTCGTCGCGGCGCAGGC
GCGGCGGCGCGGCGCGGCGCTGGTGACGCTCAACCGCCGCGAGTTCGAGCGCGTGCCCGGCCTGATGGTGACGGATTGGG
CGGCATGA
Antitoxin
Download Length: 96 a.a. Molecular weight: 10494.93 Da Isoelectric Point: 4.9057
>AT43042 WP_085770514.1 NZ_AP027149:4023294-4023581 [Methylocystis bryophila]
MTASAGKPAQEKATAKLFMHGRSQAVRLPKEFRFEGKEVRVSKVGDKVILEPLKKEPFDVEAWRGSLDALGARDFLPDGL
PDDPPLEPDDSISFD
MTASAGKPAQEKATAKLFMHGRSQAVRLPKEFRFEGKEVRVSKVGDKVILEPLKKEPFDVEAWRGSLDALGARDFLPDGL
PDDPPLEPDDSISFD
Download Length: 288 bp
>AT43042 NZ_AP027149:4023294-4023581 [Methylocystis bryophila]
ATGACCGCCAGCGCCGGCAAGCCCGCCCAAGAGAAAGCGACCGCCAAGCTGTTCATGCACGGCCGCAGCCAGGCTGTGCG
CCTGCCGAAGGAGTTCCGCTTCGAGGGGAAAGAGGTGCGCGTCAGCAAGGTAGGCGACAAGGTGATCTTGGAGCCTTTGA
AAAAGGAGCCGTTCGACGTGGAAGCCTGGCGCGGGAGTCTCGACGCCTTGGGCGCGCGGGATTTCTTGCCCGACGGTCTG
CCCGATGATCCGCCCCTCGAGCCCGACGATTCGATATCATTCGATTGA
ATGACCGCCAGCGCCGGCAAGCCCGCCCAAGAGAAAGCGACCGCCAAGCTGTTCATGCACGGCCGCAGCCAGGCTGTGCG
CCTGCCGAAGGAGTTCCGCTTCGAGGGGAAAGAGGTGCGCGTCAGCAAGGTAGGCGACAAGGTGATCTTGGAGCCTTTGA
AAAAGGAGCCGTTCGACGTGGAAGCCTGGCGCGGGAGTCTCGACGCCTTGGGCGCGCGGGATTTCTTGCCCGACGGTCTG
CCCGATGATCCGCCCCTCGAGCCCGACGATTCGATATCATTCGATTGA