Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | vapBC/VapC-VagC |
| Location | 2289547..2290178 | Replicon | chromosome |
| Accession | NZ_AP027149 | ||
| Organism | Methylocystis bryophila strain DSM 21852 | ||
Toxin (Protein)
| Gene name | vapC | Uniprot ID | - |
| Locus tag | QMG80_RS10715 | Protein ID | WP_085772819.1 |
| Coordinates | 2289547..2289945 (-) | Length | 133 a.a. |
Antitoxin (Protein)
| Gene name | vapB | Uniprot ID | - |
| Locus tag | QMG80_RS10720 | Protein ID | WP_085773816.1 |
| Coordinates | 2289945..2290178 (-) | Length | 78 a.a. |
Genomic Context
Location: 2284839..2285840 (1002 bp)
Type: Others
Protein ID: WP_085772816.1
Type: Others
Protein ID: WP_085772816.1
Location: 2285843..2286778 (936 bp)
Type: Others
Protein ID: WP_085772817.1
Type: Others
Protein ID: WP_085772817.1
Location: 2286769..2289531 (2763 bp)
Type: Others
Protein ID: WP_085772818.1
Type: Others
Protein ID: WP_085772818.1
Location: 2290314..2292767 (2454 bp)
Type: Others
Protein ID: WP_281926443.1
Type: Others
Protein ID: WP_281926443.1
Location: 2292912..2293502 (591 bp)
Type: Others
Protein ID: WP_085772821.1
Type: Others
Protein ID: WP_085772821.1
Location: 2289547..2289945 (399 bp)
Type: Toxin
Protein ID: WP_085772819.1
Type: Toxin
Protein ID: WP_085772819.1
Location: 2289945..2290178 (234 bp)
Type: Antitoxin
Protein ID: WP_085773816.1
Type: Antitoxin
Protein ID: WP_085773816.1
Location: 2293640..2294227 (588 bp)
Type: Others
Protein ID: WP_085772822.1
Type: Others
Protein ID: WP_085772822.1
Location: 2294284..2295006 (723 bp)
Type: Others
Protein ID: WP_245299970.1
Type: Others
Protein ID: WP_245299970.1
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Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| QMG80_RS10700 (DSM21852_21570) | 2284839..2285840 | + | 1002 | WP_085772816.1 | MoxR family ATPase | - |
| QMG80_RS10705 (DSM21852_21580) | 2285843..2286778 | + | 936 | WP_085772817.1 | DUF58 domain-containing protein | - |
| QMG80_RS10710 (DSM21852_21590) | 2286769..2289531 | + | 2763 | WP_085772818.1 | DUF4159 domain-containing protein | - |
| QMG80_RS10715 (DSM21852_21600) | 2289547..2289945 | - | 399 | WP_085772819.1 | type II toxin-antitoxin system VapC family toxin | Toxin |
| QMG80_RS10720 (DSM21852_21610) | 2289945..2290178 | - | 234 | WP_085773816.1 | type II toxin-antitoxin system VapB family antitoxin | Antitoxin |
| QMG80_RS10725 (DSM21852_21620) | 2290314..2292767 | + | 2454 | WP_281926443.1 | phosphoketolase family protein | - |
| QMG80_RS10730 (DSM21852_21630) | 2292912..2293502 | + | 591 | WP_085772821.1 | histidine phosphatase family protein | - |
| QMG80_RS10735 (DSM21852_21640) | 2293640..2294227 | - | 588 | WP_085772822.1 | hypothetical protein | - |
| QMG80_RS10740 (DSM21852_21650) | 2294284..2295006 | - | 723 | WP_245299970.1 | DUF3142 domain-containing protein | - |
Associated MGEs
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MGE detail | Similar MGEs | Relative position | MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| No matching records found | |||||||
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 133 a.a. Molecular weight: 14824.07 Da Isoelectric Point: 7.2911
>T43040 WP_085772819.1 NZ_AP027149:c2289945-2289547 [Methylocystis bryophila]
MLNYMLDTNICIYVMKTYPPALRDKFNGLAEQLCISSITLGELHYGAEKSARRTENLKAIEQFVARLEVLPFAEKAAAHY
GQVRAELERAGTPCGPHDMQIGGHARSEGLIVVTNNFREFARMPGVRVENWV
MLNYMLDTNICIYVMKTYPPALRDKFNGLAEQLCISSITLGELHYGAEKSARRTENLKAIEQFVARLEVLPFAEKAAAHY
GQVRAELERAGTPCGPHDMQIGGHARSEGLIVVTNNFREFARMPGVRVENWV
Download Length: 399 bp
>T43040 NZ_AP027149:c2289945-2289547 [Methylocystis bryophila]
ATGCTCAACTATATGCTGGACACAAACATCTGCATTTACGTGATGAAGACTTATCCACCCGCCCTCCGCGACAAATTCAA
TGGGTTGGCGGAGCAGCTTTGCATATCGAGCATCACGCTGGGCGAACTGCATTATGGCGCGGAGAAGTCGGCGCGACGAA
CCGAGAACTTAAAGGCAATCGAGCAATTCGTGGCGCGGCTGGAAGTGCTTCCGTTCGCGGAGAAGGCTGCCGCGCATTAC
GGGCAAGTCCGAGCCGAACTGGAGCGGGCCGGAACGCCTTGTGGTCCGCATGACATGCAGATCGGCGGTCATGCCCGCAG
CGAGGGGCTCATCGTCGTCACCAACAATTTTCGAGAATTCGCAAGAATGCCGGGCGTGAGAGTGGAGAATTGGGTGTAG
ATGCTCAACTATATGCTGGACACAAACATCTGCATTTACGTGATGAAGACTTATCCACCCGCCCTCCGCGACAAATTCAA
TGGGTTGGCGGAGCAGCTTTGCATATCGAGCATCACGCTGGGCGAACTGCATTATGGCGCGGAGAAGTCGGCGCGACGAA
CCGAGAACTTAAAGGCAATCGAGCAATTCGTGGCGCGGCTGGAAGTGCTTCCGTTCGCGGAGAAGGCTGCCGCGCATTAC
GGGCAAGTCCGAGCCGAACTGGAGCGGGCCGGAACGCCTTGTGGTCCGCATGACATGCAGATCGGCGGTCATGCCCGCAG
CGAGGGGCTCATCGTCGTCACCAACAATTTTCGAGAATTCGCAAGAATGCCGGGCGTGAGAGTGGAGAATTGGGTGTAG
Antitoxin
Download Length: 78 a.a. Molecular weight: 8912.17 Da Isoelectric Point: 8.9533
>AT43040 WP_085773816.1 NZ_AP027149:c2290178-2289945 [Methylocystis bryophila]
MTRSTVFTSNRSQAVRLPKAVAFPEEVHHVDILKIGRTRVIAPQGKRWDDLFLHGPRVTDDFMVEREQPPAETREPF
MTRSTVFTSNRSQAVRLPKAVAFPEEVHHVDILKIGRTRVIAPQGKRWDDLFLHGPRVTDDFMVEREQPPAETREPF
Download Length: 234 bp
>AT43040 NZ_AP027149:c2290178-2289945 [Methylocystis bryophila]
ATGACCCGTTCGACCGTCTTCACCAGCAATCGCAGCCAGGCCGTTCGCCTTCCAAAGGCCGTCGCCTTCCCGGAGGAGGT
CCATCACGTCGATATCCTCAAGATCGGCCGCACTCGCGTGATCGCGCCTCAGGGCAAAAGGTGGGACGACCTTTTCTTGC
ACGGGCCGCGCGTCACTGACGATTTCATGGTCGAGCGAGAGCAACCGCCCGCAGAGACTCGCGAGCCTTTCTGA
ATGACCCGTTCGACCGTCTTCACCAGCAATCGCAGCCAGGCCGTTCGCCTTCCAAAGGCCGTCGCCTTCCCGGAGGAGGT
CCATCACGTCGATATCCTCAAGATCGGCCGCACTCGCGTGATCGCGCCTCAGGGCAAAAGGTGGGACGACCTTTTCTTGC
ACGGGCCGCGCGTCACTGACGATTTCATGGTCGAGCGAGAGCAACCGCCCGCAGAGACTCGCGAGCCTTTCTGA