Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) stbE-relB/ParE-YafN
Location 895695..896223 Replicon chromosome
Accession NZ_AP027149
Organism Methylocystis bryophila strain DSM 21852

Toxin (Protein)


Gene name stbE Uniprot ID -
Locus tag QMG80_RS04115 Protein ID WP_085771662.1
Coordinates 895933..896223 (+) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag QMG80_RS04110 Protein ID WP_085771661.1
Coordinates 895695..895943 (+) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QMG80_RS04090 (DSM21852_08220) 891563..892345 + 783 WP_085771657.1 ethanolamine ammonia-lyase subunit EutC -
QMG80_RS04095 (DSM21852_08230) 892366..892644 - 279 WP_085771658.1 hypothetical protein -
QMG80_RS04100 (DSM21852_08240) 892955..893659 + 705 WP_085771659.1 type 1 glutamine amidotransferase domain-containing protein -
QMG80_RS04105 (DSM21852_08250) 893689..895431 - 1743 WP_158658714.1 DUF885 domain-containing protein -
QMG80_RS04110 (DSM21852_08260) 895695..895943 + 249 WP_085771661.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
QMG80_RS04115 (DSM21852_08270) 895933..896223 + 291 WP_085771662.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
QMG80_RS04125 (DSM21852_08280) 896637..897860 - 1224 WP_085771663.1 DNA methyltransferase -
QMG80_RS04130 (DSM21852_08290) 897983..898345 - 363 WP_245299883.1 protease inhibitor I42 family protein -
QMG80_RS04135 (DSM21852_08300) 898575..900008 + 1434 WP_102938196.1 DUF1800 family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-84)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 11381.21 Da        Isoelectric Point: 10.5908

>T43037 WP_085771662.1 NZ_AP027149:895933-896223 [Methylocystis bryophila]
MTYELAFLDDALKEWRKLDSTTRDQFKIKLAERLENPKVISARLHGAKERYKIKLRSAGFRLVYEVRDQELIVLVVAVGK
RERNEVYKTAARRRTD

Download         Length: 291 bp

>T43037 NZ_AP027149:895933-896223 [Methylocystis bryophila]
ATGACCTATGAGCTCGCCTTTCTTGACGACGCGTTGAAGGAATGGCGCAAGCTGGATAGCACCACTCGAGACCAGTTCAA
GATCAAGCTCGCCGAGCGGCTGGAAAACCCGAAAGTTATCTCCGCTCGTTTGCATGGCGCGAAAGAGCGCTACAAGATCA
AGTTGCGTAGCGCTGGTTTCCGCCTAGTCTATGAAGTTCGCGATCAGGAGTTGATCGTTCTTGTCGTGGCGGTCGGCAAG
CGCGAGCGCAACGAAGTTTACAAGACCGCCGCACGGCGGCGGACGGATTGA

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 8874.12 Da        Isoelectric Point: 4.5494

>AT43037 WP_085771661.1 NZ_AP027149:895695-895943 [Methylocystis bryophila]
MAHIVHATTVASISDLKKNPMGTVAAGEGFPVAILNRNEPAFYCIPAKAYEDLLERLEDLELNAVADAREGQAIHKISLD
DL

Download         Length: 249 bp

>AT43037 NZ_AP027149:895695-895943 [Methylocystis bryophila]
ATGGCGCATATCGTTCACGCGACCACGGTCGCGAGCATTTCGGATTTGAAGAAGAACCCCATGGGCACCGTTGCCGCCGG
CGAAGGGTTCCCCGTTGCGATCCTCAACCGCAACGAGCCTGCGTTCTATTGCATCCCTGCCAAGGCTTATGAAGATTTGC
TGGAGCGTCTCGAAGACCTCGAGCTGAACGCCGTTGCGGACGCGCGCGAAGGGCAGGCGATCCACAAGATTTCGCTCGAT
GACCTATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References