Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | vapBC/PIN-MazE |
| Location | 1942440..1943055 | Replicon | chromosome |
| Accession | NZ_AP027142 | ||
| Organism | Methylocystis iwaonis strain SS37A-Re | ||
Toxin (Protein)
| Gene name | vapC | Uniprot ID | - |
| Locus tag | QMG84_RS09315 | Protein ID | WP_281927444.1 |
| Coordinates | 1942440..1942844 (-) | Length | 135 a.a. |
Antitoxin (Protein)
| Gene name | vapB | Uniprot ID | - |
| Locus tag | QMG84_RS09320 | Protein ID | WP_281927445.1 |
| Coordinates | 1942828..1943055 (-) | Length | 76 a.a. |
Genomic Context
Location: 1937711..1942408 (4698 bp)
Type: Others
Protein ID: WP_281927442.1
Type: Others
Protein ID: WP_281927442.1
Location: 1943277..1944695 (1419 bp)
Type: Others
Protein ID: WP_281927447.1
Type: Others
Protein ID: WP_281927447.1
Location: 1944703..1944912 (210 bp)
Type: Others
Protein ID: WP_202071595.1
Type: Others
Protein ID: WP_202071595.1
Location: 1947472..1947933 (462 bp)
Type: Others
Protein ID: WP_281927451.1
Type: Others
Protein ID: WP_281927451.1
Location: 1942440..1942844 (405 bp)
Type: Toxin
Protein ID: WP_281927444.1
Type: Toxin
Protein ID: WP_281927444.1
Location: 1942828..1943055 (228 bp)
Type: Antitoxin
Protein ID: WP_281927445.1
Type: Antitoxin
Protein ID: WP_281927445.1
Location: 1945247..1945909 (663 bp)
Type: Others
Protein ID: WP_281927449.1
Type: Others
Protein ID: WP_281927449.1
Location: 1946055..1947473 (1419 bp)
Type: Others
Protein ID: WP_281927450.1
Type: Others
Protein ID: WP_281927450.1
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Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| QMG84_RS09310 (SS37A_18380) | 1937711..1942408 | + | 4698 | WP_281927442.1 | glutamate synthase large subunit | - |
| QMG84_RS09315 (SS37A_18390) | 1942440..1942844 | - | 405 | WP_281927444.1 | PIN domain-containing protein | Toxin |
| QMG84_RS09320 (SS37A_18400) | 1942828..1943055 | - | 228 | WP_281927445.1 | AbrB/MazE/SpoVT family DNA-binding domain-containing protein | Antitoxin |
| QMG84_RS09325 (SS37A_18410) | 1943277..1944695 | + | 1419 | WP_281927447.1 | glutamate synthase subunit beta | - |
| QMG84_RS09330 (SS37A_18420) | 1944703..1944912 | + | 210 | WP_202071595.1 | hypothetical protein | - |
| QMG84_RS09335 (SS37A_18430) | 1945247..1945909 | - | 663 | WP_281927449.1 | L,D-transpeptidase | - |
| QMG84_RS09340 (SS37A_18440) | 1946055..1947473 | - | 1419 | WP_281927450.1 | SGNH family hydrolase | - |
| QMG84_RS09345 (SS37A_18450) | 1947472..1947933 | + | 462 | WP_281927451.1 | hypothetical protein | - |
Associated MGEs
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MGE detail | Similar MGEs | Relative position | MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| No matching records found | |||||||
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 135 a.a. Molecular weight: 14744.83 Da Isoelectric Point: 6.2215
>T43033 WP_281927444.1 NZ_AP027142:c1942844-1942440 [Methylocystis iwaonis]
MTTRNRSFFDTNVLLYAVATSGAKADISEELIALGGVVSIQVLNEFAAVSRRKHNASWQNVKASLESFRATLDIVPLTLE
THQTGVALAERYNFAIYDAMIVAAAKLAGCRTLYTEDLHNGQILDQLKIENPFV
MTTRNRSFFDTNVLLYAVATSGAKADISEELIALGGVVSIQVLNEFAAVSRRKHNASWQNVKASLESFRATLDIVPLTLE
THQTGVALAERYNFAIYDAMIVAAAKLAGCRTLYTEDLHNGQILDQLKIENPFV
Download Length: 405 bp
>T43033 NZ_AP027142:c1942844-1942440 [Methylocystis iwaonis]
ATGACGACGAGGAATAGAAGCTTCTTCGATACGAACGTCCTTCTATACGCGGTCGCGACCTCCGGCGCCAAAGCGGATAT
CTCCGAAGAGTTGATTGCGCTCGGCGGCGTCGTCAGCATTCAGGTTCTGAACGAGTTCGCCGCCGTTTCTCGGCGCAAAC
ACAATGCTTCGTGGCAGAATGTGAAGGCGAGTTTAGAATCGTTTCGAGCGACGCTCGACATCGTTCCCCTTACCCTTGAA
ACGCACCAGACCGGCGTCGCTCTTGCCGAGCGCTACAATTTTGCAATCTATGACGCCATGATCGTGGCGGCAGCTAAATT
AGCGGGCTGCCGGACGCTCTATACGGAGGACCTGCATAATGGGCAGATCCTCGATCAACTAAAAATCGAGAACCCGTTTG
TCTGA
ATGACGACGAGGAATAGAAGCTTCTTCGATACGAACGTCCTTCTATACGCGGTCGCGACCTCCGGCGCCAAAGCGGATAT
CTCCGAAGAGTTGATTGCGCTCGGCGGCGTCGTCAGCATTCAGGTTCTGAACGAGTTCGCCGCCGTTTCTCGGCGCAAAC
ACAATGCTTCGTGGCAGAATGTGAAGGCGAGTTTAGAATCGTTTCGAGCGACGCTCGACATCGTTCCCCTTACCCTTGAA
ACGCACCAGACCGGCGTCGCTCTTGCCGAGCGCTACAATTTTGCAATCTATGACGCCATGATCGTGGCGGCAGCTAAATT
AGCGGGCTGCCGGACGCTCTATACGGAGGACCTGCATAATGGGCAGATCCTCGATCAACTAAAAATCGAGAACCCGTTTG
TCTGA
Antitoxin
Download Length: 76 a.a. Molecular weight: 8551.68 Da Isoelectric Point: 4.8779
>AT43033 WP_281927445.1 NZ_AP027142:c1943055-1942828 [Methylocystis iwaonis]
MRVSRWGNSLAVRLPADLVREKGLKEGDEVSITVESMIDEKARARAEAIAALRNLRGMIPADYRFKREDAYDDEE
MRVSRWGNSLAVRLPADLVREKGLKEGDEVSITVESMIDEKARARAEAIAALRNLRGMIPADYRFKREDAYDDEE
Download Length: 228 bp
>AT43033 NZ_AP027142:c1943055-1942828 [Methylocystis iwaonis]
ATGCGCGTCTCACGATGGGGAAATAGCCTTGCCGTGCGCCTGCCCGCCGACCTCGTGCGGGAGAAGGGCCTGAAGGAAGG
CGACGAGGTATCGATCACGGTCGAGTCGATGATCGACGAAAAAGCCCGCGCTCGCGCCGAGGCGATCGCTGCTCTCCGGA
ACCTTCGCGGGATGATCCCGGCCGATTACAGGTTCAAACGCGAAGACGCATATGACGACGAGGAATAG
ATGCGCGTCTCACGATGGGGAAATAGCCTTGCCGTGCGCCTGCCCGCCGACCTCGTGCGGGAGAAGGGCCTGAAGGAAGG
CGACGAGGTATCGATCACGGTCGAGTCGATGATCGACGAAAAAGCCCGCGCTCGCGCCGAGGCGATCGCTGCTCTCCGGA
ACCTTCGCGGGATGATCCCGGCCGATTACAGGTTCAAACGCGAAGACGCATATGACGACGAGGAATAG