Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) relBE/YoeB-YefM
Location 1371721..1372226 Replicon chromosome
Accession NZ_AP027142
Organism Methylocystis iwaonis strain SS37A-Re

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag QMG84_RS06555 Protein ID WP_281931274.1
Coordinates 1371972..1372226 (+) Length 85 a.a.

Antitoxin (Protein)


Gene name relE Uniprot ID -
Locus tag QMG84_RS06550 Protein ID WP_165047956.1
Coordinates 1371721..1371975 (+) Length 85 a.a.

Genomic Context


QMG84_RS06530QMG84_RS06535QMG84_RS06540QMG84_RS06545QMG84_RS06550QMG84_RS06555QMG84_RS06560QMG84_RS06580QMG84_RS06585QMG84_RS06565QMG84_RS06570QMG84_RS06575
Location: 1367889..1368161 (273 bp)
Type: Others
Protein ID: WP_281931268.1
Location: 1368342..1368989 (648 bp)
Type: Others
Protein ID: WP_281931270.1
Location: 1369225..1369719 (495 bp)
Type: Others
Protein ID: WP_281931271.1
Location: 1369861..1371669 (1809 bp)
Type: Others
Protein ID: WP_281931272.1
Location: 1371721..1371975 (255 bp)
Type: Antitoxin
Protein ID: WP_165047956.1
Location: 1371972..1372226 (255 bp)
Type: Toxin
Protein ID: WP_281931274.1
Location: 1372588..1372671 (84 bp)
Type: Others
Protein ID: WP_281931936.1
Location: 1375336..1375668 (333 bp)
Type: Others
Protein ID: WP_281931280.1
Location: 1375757..1376020 (264 bp)
Type: Others
Protein ID: WP_281931282.1
Location: 1372726..1373628 (903 bp)
Type: Others
Protein ID: WP_281931276.1
Location: 1373746..1374480 (735 bp)
Type: Others
Protein ID: WP_281931277.1
Location: 1374534..1375235 (702 bp)
Type: Others
Protein ID: WP_281931279.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
QMG84_RS06530 (SS37A_12880)1367889..1368161+273WP_281931268.1hypothetical protein-
QMG84_RS06535 (SS37A_12890)1368342..1368989+648WP_281931270.1hypothetical protein-
QMG84_RS06540 (SS37A_12900)1369225..1369719+495WP_281931271.1hypothetical protein-
QMG84_RS06545 (SS37A_12910)1369861..1371669+1809WP_281931272.1translation elongation factor 4-
QMG84_RS06550 (SS37A_12920)1371721..1371975+255WP_165047956.1type II toxin-antitoxin system prevent-host-death family antitoxinAntitoxin
QMG84_RS06555 (SS37A_12930)1371972..1372226+255WP_281931274.1Txe/YoeB family addiction module toxinToxin
QMG84_RS065601372588..1372671+84WP_281931936.1hypothetical protein-
QMG84_RS06565 (SS37A_12940)1372726..1373628-903WP_281931276.1EamA family transporter-
QMG84_RS06570 (SS37A_12950)1373746..1374480-735WP_281931277.1class I SAM-dependent methyltransferase-
QMG84_RS06575 (SS37A_12960)1374534..1375235-702WP_281931279.1MOSC domain-containing protein-
QMG84_RS06580 (SS37A_12970)1375336..1375668+333WP_281931280.1hypothetical protein-
QMG84_RS06585 (SS37A_12980)1375757..1376020+264WP_281931282.1hypothetical protein-

Associated MGEs


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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(5-84)

Antitoxin

(1-75)


Sequences


Toxin        


Download         Length: 85 a.a.        Molecular weight: 10065.54 Da        Isoelectric Point: 8.5222

>T43032 WP_281931274.1 NZ_AP027142:1371972-1372226 [Methylocystis iwaonis]
MKLIFSESAWEDYLHWQAQDAKILERINSLIKECQRTPFTGTGKPEPLRGDLRGWWSRRITLEHRLVYRVEGESLLIAQC
RHHY

Download         Length: 255 bp

>T43032 NZ_AP027142:1371972-1372226 [Methylocystis iwaonis]
ATGAAGCTCATCTTCTCGGAAAGCGCCTGGGAGGATTATCTCCACTGGCAGGCGCAGGACGCGAAGATTCTCGAACGCAT
TAATTCACTCATCAAGGAATGCCAGCGCACGCCTTTTACAGGCACTGGAAAGCCCGAGCCTTTGCGGGGGGATTTACGGG
GCTGGTGGTCTCGGCGGATTACGCTGGAGCATCGCCTGGTATATCGCGTCGAAGGCGAGAGCCTGCTGATTGCGCAGTGT
CGCCATCATTATTGA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9335.52 Da        Isoelectric Point: 5.1767

>AT43032 WP_165047956.1 NZ_AP027142:1371721-1371975 [Methylocystis iwaonis]
MRTTSYSDLRKNLAATLDRVTEDHEPVVITRDRGKPAAVLISLEDFASYEETAYLLKSPRNAERLLASIKELEAGGGAER
KLSE

Download         Length: 255 bp

>AT43032 NZ_AP027142:1371721-1371975 [Methylocystis iwaonis]
ATGCGCACGACCTCCTACAGCGACCTCCGGAAGAACCTCGCGGCCACGCTCGATCGCGTGACCGAGGACCACGAGCCTGT
CGTCATCACCCGTGACCGCGGAAAGCCGGCGGCCGTGCTGATCTCCCTCGAAGATTTCGCCTCCTATGAGGAGACGGCCT
ATCTGCTGAAAAGCCCGCGCAACGCCGAGCGCCTGCTTGCGTCGATCAAAGAACTCGAAGCTGGCGGCGGCGCAGAGCGT
AAGCTTTCCGAATGA

Similar Proteins


Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures


Toxin

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Source
ID
Structure
No matching records found


Antitoxin

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Source
ID
Structure
No matching records found

References