Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YoeB-YefM
Location 1371721..1372226 Replicon chromosome
Accession NZ_AP027142
Organism Methylocystis iwaonis strain SS37A-Re

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag QMG84_RS06555 Protein ID WP_281931274.1
Coordinates 1371972..1372226 (+) Length 85 a.a.

Antitoxin (Protein)


Gene name relE Uniprot ID -
Locus tag QMG84_RS06550 Protein ID WP_165047956.1
Coordinates 1371721..1371975 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QMG84_RS06530 (SS37A_12880) 1367889..1368161 + 273 WP_281931268.1 hypothetical protein -
QMG84_RS06535 (SS37A_12890) 1368342..1368989 + 648 WP_281931270.1 hypothetical protein -
QMG84_RS06540 (SS37A_12900) 1369225..1369719 + 495 WP_281931271.1 hypothetical protein -
QMG84_RS06545 (SS37A_12910) 1369861..1371669 + 1809 WP_281931272.1 translation elongation factor 4 -
QMG84_RS06550 (SS37A_12920) 1371721..1371975 + 255 WP_165047956.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
QMG84_RS06555 (SS37A_12930) 1371972..1372226 + 255 WP_281931274.1 Txe/YoeB family addiction module toxin Toxin
QMG84_RS06560 1372588..1372671 + 84 WP_281931936.1 hypothetical protein -
QMG84_RS06565 (SS37A_12940) 1372726..1373628 - 903 WP_281931276.1 EamA family transporter -
QMG84_RS06570 (SS37A_12950) 1373746..1374480 - 735 WP_281931277.1 class I SAM-dependent methyltransferase -
QMG84_RS06575 (SS37A_12960) 1374534..1375235 - 702 WP_281931279.1 MOSC domain-containing protein -
QMG84_RS06580 (SS37A_12970) 1375336..1375668 + 333 WP_281931280.1 hypothetical protein -
QMG84_RS06585 (SS37A_12980) 1375757..1376020 + 264 WP_281931282.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-75)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 10065.54 Da        Isoelectric Point: 8.5222

>T43032 WP_281931274.1 NZ_AP027142:1371972-1372226 [Methylocystis iwaonis]
MKLIFSESAWEDYLHWQAQDAKILERINSLIKECQRTPFTGTGKPEPLRGDLRGWWSRRITLEHRLVYRVEGESLLIAQC
RHHY

Download         Length: 255 bp

>T43032 NZ_AP027142:1371972-1372226 [Methylocystis iwaonis]
ATGAAGCTCATCTTCTCGGAAAGCGCCTGGGAGGATTATCTCCACTGGCAGGCGCAGGACGCGAAGATTCTCGAACGCAT
TAATTCACTCATCAAGGAATGCCAGCGCACGCCTTTTACAGGCACTGGAAAGCCCGAGCCTTTGCGGGGGGATTTACGGG
GCTGGTGGTCTCGGCGGATTACGCTGGAGCATCGCCTGGTATATCGCGTCGAAGGCGAGAGCCTGCTGATTGCGCAGTGT
CGCCATCATTATTGA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9335.52 Da        Isoelectric Point: 5.1767

>AT43032 WP_165047956.1 NZ_AP027142:1371721-1371975 [Methylocystis iwaonis]
MRTTSYSDLRKNLAATLDRVTEDHEPVVITRDRGKPAAVLISLEDFASYEETAYLLKSPRNAERLLASIKELEAGGGAER
KLSE

Download         Length: 255 bp

>AT43032 NZ_AP027142:1371721-1371975 [Methylocystis iwaonis]
ATGCGCACGACCTCCTACAGCGACCTCCGGAAGAACCTCGCGGCCACGCTCGATCGCGTGACCGAGGACCACGAGCCTGT
CGTCATCACCCGTGACCGCGGAAAGCCGGCGGCCGTGCTGATCTCCCTCGAAGATTTCGCCTCCTATGAGGAGACGGCCT
ATCTGCTGAAAAGCCCGCGCAACGCCGAGCGCCTGCTTGCGTCGATCAAAGAACTCGAAGCTGGCGGCGGCGCAGAGCGT
AAGCTTTCCGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References