Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumA-relB/upstrm_HI1419-dnstrm_HI1420
Location 1965152..1965746 Replicon chromosome
Accession NZ_AP027058
Organism Limnohabitans sp. MORI2

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag QMG27_RS09325 Protein ID WP_281810778.1
Coordinates 1965432..1965746 (-) Length 105 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag QMG27_RS09320 Protein ID WP_281814595.1
Coordinates 1965152..1965445 (-) Length 98 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QMG27_RS09305 (LMORI2_18190) 1960612..1962612 + 2001 WP_281810775.1 transketolase -
QMG27_RS09310 (LMORI2_18200) 1962679..1963641 + 963 WP_281810776.1 D-2-hydroxyacid dehydrogenase -
QMG27_RS09315 (LMORI2_18210) 1963745..1965148 + 1404 WP_281810777.1 8-oxoguanine deaminase -
QMG27_RS09320 (LMORI2_18220) 1965152..1965445 - 294 WP_281814595.1 putative addiction module antidote protein Antitoxin
QMG27_RS09325 (LMORI2_18230) 1965432..1965746 - 315 WP_281810778.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
QMG27_RS09330 (LMORI2_18240) 1965884..1966234 + 351 WP_281810779.1 CidA/LrgA family protein -
QMG27_RS09335 (LMORI2_18250) 1966227..1966967 + 741 WP_281810780.1 LrgB family protein -
QMG27_RS09340 (LMORI2_18260) 1966964..1967284 - 321 WP_281810781.1 transcriptional regulator -
QMG27_RS09345 (LMORI2_18270) 1967287..1967616 - 330 WP_281810782.1 type II toxin-antitoxin system RelE/ParE family toxin -
QMG27_RS09350 (LMORI2_18280) 1967701..1968789 - 1089 WP_281810783.1 molybdenum ABC transporter ATP-binding protein -
QMG27_RS09355 (LMORI2_18290) 1968786..1969478 - 693 WP_281810784.1 molybdate ABC transporter permease subunit -
QMG27_RS09360 (LMORI2_18300) 1969488..1970249 - 762 WP_281810785.1 molybdate ABC transporter substrate-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(18-95)

Antitoxin

Uncharacterized protein HI1420

(5-94)


Sequences

Toxin        


Download         Length: 105 a.a.        Molecular weight: 11706.51 Da        Isoelectric Point: 10.6230

>T42979 WP_281810778.1 NZ_AP027058:c1965746-1965432 [Limnohabitans sp. MORI2]
MDTIKRYHLEQTSAFSRWLKNLKDLQAKAAIVLRLKQVQAGHLGDVKSVGGGVSELRWHLGPGYRVYFCKRGDQIILLLA
GGDKSTQQRDIVRAQQLAKEHTHG

Download         Length: 315 bp

>T42979 NZ_AP027058:c1965746-1965432 [Limnohabitans sp. MORI2]
ATGGATACAATAAAGCGATACCACCTAGAGCAAACATCTGCGTTCAGTCGCTGGCTTAAAAATCTGAAGGACTTGCAAGC
CAAAGCAGCCATTGTGTTGCGGCTCAAGCAAGTGCAAGCGGGTCACTTGGGTGATGTGAAGTCTGTGGGAGGTGGGGTAT
CAGAACTGCGATGGCACTTGGGGCCGGGCTATCGCGTGTATTTTTGTAAGCGTGGAGATCAGATTATTTTGTTGCTCGCG
GGCGGCGACAAGTCAACACAGCAGCGAGACATCGTTCGCGCCCAACAATTGGCCAAGGAGCATACGCATGGGTAA

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 10471.95 Da        Isoelectric Point: 5.6785

>AT42979 WP_281814595.1 NZ_AP027058:c1965445-1965152 [Limnohabitans sp. MORI2]
IRMGKTTEFDAASYLDSEEMIAEYLNQALASGDTDLLLSAIGDVAKARGMAQIARDTGLGRESLYKAFAVGAKPRFDTVL
KVLRALGVEIHAYPQAH

Download         Length: 294 bp

>AT42979 NZ_AP027058:c1965445-1965152 [Limnohabitans sp. MORI2]
ATACGCATGGGTAAGACAACAGAATTCGACGCAGCCAGTTACCTCGATAGCGAGGAGATGATCGCCGAGTACCTGAACCA
AGCTTTAGCTAGCGGTGACACTGACTTGTTGCTCTCTGCCATTGGCGACGTGGCCAAAGCCAGAGGCATGGCACAGATAG
CGCGGGACACGGGCTTGGGGCGCGAGAGTTTGTACAAAGCCTTTGCGGTAGGCGCTAAGCCGCGCTTTGACACGGTGCTT
AAAGTATTGCGTGCTTTGGGCGTTGAAATACACGCCTATCCACAAGCGCACTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References