Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 1115916..1116565 Replicon chromosome
Accession NZ_AP027056
Organism Limnohabitans sp. TEGF004

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag LINBF2_RS05605 Protein ID WP_104797520.1
Coordinates 1116149..1116565 (+) Length 139 a.a.

Antitoxin (Protein)


Gene name VapB1 Uniprot ID -
Locus tag LINBF2_RS05600 Protein ID WP_104797521.1
Coordinates 1115916..1116146 (+) Length 77 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LINBF2_RS05575 (LTEGF4_11020) 1111258..1111542 - 285 WP_281891062.1 DnaJ domain-containing protein -
LINBF2_RS05580 (LTEGF4_11030) 1111577..1112101 - 525 WP_281891063.1 GNAT family N-acetyltransferase -
LINBF2_RS05585 (LTEGF4_11040) 1112225..1113193 + 969 WP_281891064.1 tRNA-dihydrouridine synthase -
LINBF2_RS05590 (LTEGF4_11050) 1113190..1113696 + 507 WP_281891065.1 hypothetical protein -
LINBF2_RS05595 (LTEGF4_11060) 1113790..1115859 + 2070 WP_281891066.1 DEAD/DEAH box helicase -
LINBF2_RS05600 (LTEGF4_11070) 1115916..1116146 + 231 WP_104797521.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
LINBF2_RS05605 (LTEGF4_11080) 1116149..1116565 + 417 WP_104797520.1 type II toxin-antitoxin system VapC family toxin Toxin
LINBF2_RS05610 (LTEGF4_11090) 1116569..1117747 + 1179 WP_281891068.1 YbfB/YjiJ family MFS transporter -
LINBF2_RS05615 (LTEGF4_11100) 1117866..1119593 + 1728 WP_281891069.1 30S ribosomal protein S12 methylthiotransferase accessory factor YcaO -
LINBF2_RS05620 (LTEGF4_11110) 1119666..1120373 - 708 WP_281891071.1 VOC family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(8-129)

Antitoxin

SpoVT-AbrB domain

(7-43)


Sequences

Toxin        


Download         Length: 139 a.a.        Molecular weight: 15468.74 Da        Isoelectric Point: 7.3845

>T42974 WP_104797520.1 NZ_AP027056:1116149-1116565 [Limnohabitans sp. TEGF004]
MAVQLNRYLLDTNICIYIAKGQPLAVRHRFESHTLQELAMSTITVGELRFGAEKSQSRDRALATIAQLVQMIQPCALPMA
AAEHYGHVRASLQQQGMPIGNNDLWLAAHALAEGWTLVTNNTREFSRVQGLRVENWVE

Download         Length: 417 bp

>T42974 NZ_AP027056:1116149-1116565 [Limnohabitans sp. TEGF004]
ATGGCCGTGCAGCTAAATCGCTATCTCTTAGATACCAATATTTGCATTTACATCGCTAAGGGACAGCCGCTGGCTGTGCG
CCATCGGTTTGAGTCGCACACGCTTCAAGAGTTGGCCATGTCTACGATCACGGTGGGTGAATTGCGGTTTGGTGCAGAAA
AAAGTCAGTCTCGTGATCGTGCGTTAGCGACTATTGCGCAATTGGTTCAAATGATCCAGCCGTGTGCCTTACCCATGGCG
GCGGCTGAACATTACGGTCATGTGCGAGCCTCCTTACAGCAGCAGGGCATGCCAATTGGAAATAACGATCTTTGGTTAGC
CGCTCATGCTCTAGCCGAAGGTTGGACTTTGGTGACGAACAACACGCGTGAGTTCAGCCGAGTGCAGGGGTTACGCGTTG
AAAACTGGGTTGAGTAA

Antitoxin


Download         Length: 77 a.a.        Molecular weight: 8516.53 Da        Isoelectric Point: 4.4295

>AT42974 WP_104797521.1 NZ_AP027056:1115916-1116146 [Limnohabitans sp. TEGF004]
MTYARVFQSGNSQAVRLPKEFRFDTDQVEIFRQGSDIVLRQVPTNAGAVFDLLSSLPADFMADGRQDAPPQEREAL

Download         Length: 231 bp

>AT42974 NZ_AP027056:1115916-1116146 [Limnohabitans sp. TEGF004]
ATGACATATGCCCGTGTTTTTCAGTCTGGCAACAGCCAAGCTGTGCGTTTACCTAAAGAGTTTCGATTTGACACAGATCA
GGTCGAAATATTTCGACAGGGCAGTGACATTGTGCTGCGCCAAGTGCCTACCAACGCGGGCGCCGTGTTCGATTTACTAA
GTAGCTTGCCCGCAGACTTTATGGCCGATGGCCGCCAAGACGCACCGCCTCAAGAGCGCGAGGCGCTTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References