Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumA-relB/upstrm_HI1419-dnstrm_HI1420
Location 513065..513670 Replicon chromosome
Accession NZ_AP027055
Organism Limnohabitans sp. INBF002

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag QMG15_RS02605 Protein ID WP_281789354.1
Coordinates 513065..513373 (+) Length 103 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag QMG15_RS02610 Protein ID WP_281789355.1
Coordinates 513383..513670 (+) Length 96 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QMG15_RS02585 (LINBF2_05170) 508514..509194 - 681 WP_281789349.1 phosphoribosylanthranilate isomerase -
QMG15_RS02590 (LINBF2_05180) 509191..509988 - 798 WP_281789351.1 tRNA pseudouridine(38-40) synthase TruA -
QMG15_RS02595 (LINBF2_05190) 509994..511622 - 1629 WP_281789352.1 FimV/HubP family polar landmark protein -
QMG15_RS02600 (LINBF2_05200) 511644..512774 - 1131 WP_281789353.1 aspartate-semialdehyde dehydrogenase -
QMG15_RS02605 (LINBF2_05210) 513065..513373 + 309 WP_281789354.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
QMG15_RS02610 (LINBF2_05220) 513383..513670 + 288 WP_281789355.1 putative addiction module antidote protein Antitoxin
QMG15_RS02615 (LINBF2_05230) 513717..514802 - 1086 WP_281789356.1 3-isopropylmalate dehydrogenase -
QMG15_RS02620 (LINBF2_05240) 514836..515480 - 645 WP_104801555.1 3-isopropylmalate dehydratase small subunit -
QMG15_RS02625 (LINBF2_05250) 515480..515614 - 135 WP_281789357.1 entericidin A/B family lipoprotein -
QMG15_RS02630 (LINBF2_05260) 515630..517051 - 1422 WP_281789358.1 3-isopropylmalate dehydratase large subunit -
QMG15_RS02635 (LINBF2_05270) 517187..518551 + 1365 WP_281789359.1 carbohydrate porin -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(8-102)

Antitoxin

Uncharacterized protein HI1420

(4-94)


Sequences

Toxin        


Download         Length: 103 a.a.        Molecular weight: 11549.33 Da        Isoelectric Point: 10.3319

>T42970 WP_281789354.1 NZ_AP027055:513065-513373 [Limnohabitans sp. INBF002]
MEYNQAPIEIRQTEHYVRWFAALRDRTARARIDIRIRRMSLGNLGDVKAVGAGVSELRIDYGPGYRIYFVQRGTQLVVLL
AGGDKGSQSRDIAMAHELAKML

Download         Length: 309 bp

>T42970 NZ_AP027055:513065-513373 [Limnohabitans sp. INBF002]
ATGGAATACAATCAAGCCCCGATTGAAATTAGGCAAACAGAGCATTACGTTCGCTGGTTTGCCGCGTTGCGAGACCGCAC
AGCAAGGGCTCGAATTGATATTCGAATTCGTCGAATGTCTTTGGGAAACCTCGGTGATGTGAAGGCTGTGGGTGCAGGCG
TATCTGAGCTGCGTATTGATTACGGGCCGGGTTATCGAATTTATTTTGTTCAGCGTGGCACGCAGCTTGTGGTGCTGCTG
GCTGGTGGTGATAAGGGCAGTCAGTCGCGAGATATCGCGATGGCGCATGAACTGGCCAAGATGCTTTAG

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 10010.26 Da        Isoelectric Point: 4.7769

>AT42970 WP_281789355.1 NZ_AP027055:513383-513670 [Limnohabitans sp. INBF002]
MANNATRAWDAAEHLQTEEDMAAYLEAALEEGDSSLIAAALGDIARAKGMSQVARDTGLGRESLYKALSSTGNPELATII
KVVRALGLRLHATAQ

Download         Length: 288 bp

>AT42970 NZ_AP027055:513383-513670 [Limnohabitans sp. INBF002]
ATGGCAAACAATGCAACACGGGCATGGGATGCAGCAGAGCATCTGCAAACCGAAGAAGACATGGCTGCCTATTTAGAGGC
AGCTTTAGAGGAGGGTGATTCCTCTTTGATCGCTGCTGCGCTGGGGGACATCGCTCGCGCGAAGGGCATGTCGCAAGTGG
CTCGCGATACAGGACTTGGACGTGAGAGCCTTTACAAAGCTTTGTCGTCCACGGGCAACCCTGAGCTGGCCACCATCATC
AAAGTTGTGCGCGCTTTAGGGCTACGGCTTCACGCCACGGCTCAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References