42967

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) sanaTA/AbiEii-DUF6088
Location 954235..955594 Replicon chromosome
Accession NZ_AP027053
Organism Vibrio nigripulchritudo strain TUMSAT-V.nig3

Toxin (Protein)


Gene name sanaT Uniprot ID -
Locus tag QMG88_RS22930 Protein ID WP_281832453.1
Coordinates 954641..955594 (+) Length 318 a.a.

Antitoxin (Protein)


Gene name sanaA Uniprot ID -
Locus tag QMG88_RS22925 Protein ID WP_281832451.1
Coordinates 954235..954639 (+) Length 135 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QMG88_RS22900 (TUMSATVNIG3_44670) 949268..950617 - 1350 WP_281832444.1 GGDEF domain-containing protein -
QMG88_RS22905 (TUMSATVNIG3_44680) 950614..951615 - 1002 WP_281832446.1 ABC transporter substrate-binding protein -
QMG88_RS22910 (TUMSATVNIG3_44690) 952117..953292 + 1176 WP_281832448.1 MFS transporter -
QMG88_RS22915 (TUMSATVNIG3_44700) 953360..953575 + 216 WP_004405721.1 DUF3820 family protein -
QMG88_RS22920 (TUMSATVNIG3_44710) 953615..953857 + 243 WP_281832450.1 hypothetical protein -
QMG88_RS22925 (TUMSATVNIG3_44720) 954235..954639 + 405 WP_281832451.1 DUF6088 family protein Antitoxin
QMG88_RS22930 (TUMSATVNIG3_44730) 954641..955594 + 954 WP_281832453.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
QMG88_RS22935 955706..955912 + 207 WP_281832708.1 hypothetical protein -
QMG88_RS22940 (TUMSATVNIG3_44750) 957237..959309 + 2073 WP_281832455.1 hypothetical protein -
QMG88_RS22945 (TUMSATVNIG3_44760) 959710..960192 + 483 WP_281832457.1 CIA30 family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(39-304)

Antitoxin

Protein of unknown function DUF6088

(9-129)


Sequences

Toxin        


Download         Length: 318 a.a.        Molecular weight: 36637.37 Da        Isoelectric Point: 5.0861

>T42967 WP_281832453.1 NZ_AP027053:954641-955594 [Vibrio nigripulchritudo]
MEKLKQQFLEVSDVLELGNPAIIEKDYWVVALLSELAKVKAASHQMVFSGGTALAKSNVKILRMSEDVDIKLIPKPAFNE
LSRAKKKAVRKICINEVEQAITQSKLFTIEERTVNDEYRYVEFEFRYPQQFSQSPCLRPIIKLELMETIPLLDVEPRSIQ
SLVAELYKQPQEVSAFDCISIHATLVEKVISMLRRTMSVKRDVQRKDDATLVRHIYDVYCILKTEEQTESLDLEALTPLF
KSVLEEDIERFGSQHAEFVVNPKQELQLGLQEIEENPAFRQRFQDFVTPMVFSAEPHDFDTCFTSFKRIAELLIKTI

Download         Length: 954 bp

>T42967 NZ_AP027053:954641-955594 [Vibrio nigripulchritudo]
ATGGAAAAACTAAAACAACAATTCCTTGAGGTTTCCGATGTGCTTGAGCTCGGAAACCCAGCCATCATTGAAAAAGATTA
TTGGGTTGTTGCGCTATTGTCTGAGCTAGCTAAAGTGAAAGCAGCCTCTCATCAAATGGTCTTTTCTGGCGGTACAGCCC
TTGCAAAATCAAACGTTAAAATTCTTAGAATGTCAGAAGATGTAGACATTAAGTTAATCCCCAAACCAGCGTTTAATGAG
CTAAGCCGCGCTAAAAAGAAAGCGGTTCGTAAAATATGCATTAATGAGGTTGAACAGGCCATCACTCAATCAAAGCTATT
TACGATTGAAGAGCGTACTGTAAATGATGAATATCGATATGTTGAATTCGAATTCAGATACCCACAGCAATTTAGCCAGT
CACCATGCCTTCGCCCCATTATTAAACTGGAGTTGATGGAAACAATCCCGTTACTCGATGTAGAACCTCGTAGTATTCAA
TCACTGGTTGCAGAGCTATATAAACAACCACAAGAAGTGAGCGCTTTCGATTGTATTTCTATCCACGCTACTTTAGTCGA
AAAAGTAATTTCAATGTTGCGCCGTACCATGTCGGTGAAGCGAGATGTACAGCGTAAGGATGATGCCACACTGGTACGCC
ATATCTATGATGTTTACTGCATTTTAAAGACAGAAGAGCAGACAGAAAGCCTAGACCTTGAGGCGCTAACACCGTTATTT
AAATCAGTGTTAGAAGAGGATATTGAGCGTTTTGGCAGTCAACATGCAGAGTTTGTTGTCAACCCAAAACAAGAGCTACA
ACTCGGATTGCAAGAAATTGAAGAAAACCCAGCCTTCCGCCAACGCTTCCAAGACTTTGTTACGCCAATGGTGTTTAGCG
CCGAGCCTCATGATTTTGATACCTGTTTTACGTCTTTTAAGCGCATTGCAGAGTTGTTAATTAAAACAATTTAA

Antitoxin


Download         Length: 135 a.a.        Molecular weight: 15161.42 Da        Isoelectric Point: 10.6056

>AT42967 WP_281832451.1 NZ_AP027053:954235-954639 [Vibrio nigripulchritudo]
MTAVDRVYQKIKRSRRYVFERKDFDGFASYDQIGRALRQLVKQGELIKLGYGLYTKARINSLTGKPMPTNPGGSDALMRE
ILKMKGVDFEIDSLSLQSLSGESNQIPSSVQYSWNPKQFNRKLVVGNRVLNSPG

Download         Length: 405 bp

>AT42967 NZ_AP027053:954235-954639 [Vibrio nigripulchritudo]
ATGACAGCAGTTGATCGTGTTTATCAAAAGATAAAGCGTTCCAGACGCTATGTTTTTGAGCGCAAAGACTTTGATGGTTT
TGCCAGCTACGACCAAATTGGTCGAGCGCTAAGGCAGTTGGTCAAACAAGGTGAGTTAATAAAGCTTGGCTATGGTCTCT
ACACCAAGGCAAGGATTAACAGTTTAACAGGCAAACCTATGCCCACTAACCCCGGTGGAAGCGATGCTCTTATGCGTGAG
ATTTTAAAGATGAAAGGCGTCGATTTTGAGATAGACAGCCTATCTTTGCAAAGCCTGTCCGGTGAAAGCAACCAAATTCC
ATCATCCGTTCAATACTCGTGGAACCCCAAACAGTTTAATCGCAAATTGGTTGTCGGTAACCGAGTATTAAATTCGCCAG
GCTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References