42964

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) sanaTA/AbiEii-DUF6088
Location 954223..955582 Replicon chromosome
Accession NZ_AP027050
Organism Vibrio nigripulchritudo strain TUMSAT-V.nig2

Toxin (Protein)


Gene name sanaT Uniprot ID -
Locus tag QMG91_RS22685 Protein ID WP_281832453.1
Coordinates 954629..955582 (+) Length 318 a.a.

Antitoxin (Protein)


Gene name sanaA Uniprot ID -
Locus tag QMG91_RS22680 Protein ID WP_281832451.1
Coordinates 954223..954627 (+) Length 135 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QMG91_RS22655 (TUMSATVNIG2_44140) 949255..950604 - 1350 WP_281832444.1 GGDEF domain-containing protein -
QMG91_RS22660 (TUMSATVNIG2_44150) 950601..951602 - 1002 WP_281832446.1 ABC transporter substrate-binding protein -
QMG91_RS22665 (TUMSATVNIG2_44160) 952105..953280 + 1176 WP_281832448.1 MFS transporter -
QMG91_RS22670 (TUMSATVNIG2_44170) 953348..953563 + 216 WP_004405721.1 DUF3820 family protein -
QMG91_RS22675 (TUMSATVNIG2_44180) 953603..953845 + 243 WP_281832450.1 hypothetical protein -
QMG91_RS22680 (TUMSATVNIG2_44190) 954223..954627 + 405 WP_281832451.1 DUF6088 family protein Antitoxin
QMG91_RS22685 (TUMSATVNIG2_44200) 954629..955582 + 954 WP_281832453.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
QMG91_RS22690 955694..955900 + 207 WP_281832708.1 hypothetical protein -
QMG91_RS22695 (TUMSATVNIG2_44220) 957225..959297 + 2073 WP_281832455.1 hypothetical protein -
QMG91_RS22700 (TUMSATVNIG2_44230) 959698..960180 + 483 WP_281832457.1 CIA30 family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(39-304)

Antitoxin

Protein of unknown function DUF6088

(9-129)


Sequences

Toxin        


Download         Length: 318 a.a.        Molecular weight: 36637.37 Da        Isoelectric Point: 5.0861

>T42964 WP_281832453.1 NZ_AP027050:954629-955582 [Vibrio nigripulchritudo]
MEKLKQQFLEVSDVLELGNPAIIEKDYWVVALLSELAKVKAASHQMVFSGGTALAKSNVKILRMSEDVDIKLIPKPAFNE
LSRAKKKAVRKICINEVEQAITQSKLFTIEERTVNDEYRYVEFEFRYPQQFSQSPCLRPIIKLELMETIPLLDVEPRSIQ
SLVAELYKQPQEVSAFDCISIHATLVEKVISMLRRTMSVKRDVQRKDDATLVRHIYDVYCILKTEEQTESLDLEALTPLF
KSVLEEDIERFGSQHAEFVVNPKQELQLGLQEIEENPAFRQRFQDFVTPMVFSAEPHDFDTCFTSFKRIAELLIKTI

Download         Length: 954 bp

>T42964 NZ_AP027050:954629-955582 [Vibrio nigripulchritudo]
ATGGAAAAACTAAAACAACAATTCCTTGAGGTTTCCGATGTGCTTGAGCTCGGAAACCCAGCCATCATTGAAAAAGATTA
TTGGGTTGTTGCGCTATTGTCTGAGCTAGCTAAAGTGAAAGCAGCCTCTCATCAAATGGTCTTTTCTGGCGGTACAGCCC
TTGCAAAATCAAACGTTAAAATTCTTAGAATGTCAGAAGATGTAGACATTAAGTTAATCCCCAAACCAGCGTTTAATGAG
CTAAGCCGCGCTAAAAAGAAAGCGGTTCGTAAAATATGCATTAATGAGGTTGAACAGGCCATCACTCAATCAAAGCTATT
TACGATTGAAGAGCGTACTGTAAATGATGAATATCGATATGTTGAATTCGAATTCAGATACCCACAGCAATTTAGCCAGT
CACCATGCCTTCGCCCCATTATTAAACTGGAGTTGATGGAAACAATCCCGTTACTCGATGTAGAACCTCGTAGTATTCAA
TCACTGGTTGCAGAGCTATATAAACAACCACAAGAAGTGAGCGCTTTCGATTGTATTTCTATCCACGCTACTTTAGTCGA
AAAAGTAATTTCAATGTTGCGCCGTACCATGTCGGTGAAGCGAGATGTACAGCGTAAGGATGATGCCACACTGGTACGCC
ATATCTATGATGTTTACTGCATTTTAAAGACAGAAGAGCAGACAGAAAGCCTAGACCTTGAGGCGCTAACACCGTTATTT
AAATCAGTGTTAGAAGAGGATATTGAGCGTTTTGGCAGTCAACATGCAGAGTTTGTTGTCAACCCAAAACAAGAGCTACA
ACTCGGATTGCAAGAAATTGAAGAAAACCCAGCCTTCCGCCAACGCTTCCAAGACTTTGTTACGCCAATGGTGTTTAGCG
CCGAGCCTCATGATTTTGATACCTGTTTTACGTCTTTTAAGCGCATTGCAGAGTTGTTAATTAAAACAATTTAA

Antitoxin


Download         Length: 135 a.a.        Molecular weight: 15161.42 Da        Isoelectric Point: 10.6056

>AT42964 WP_281832451.1 NZ_AP027050:954223-954627 [Vibrio nigripulchritudo]
MTAVDRVYQKIKRSRRYVFERKDFDGFASYDQIGRALRQLVKQGELIKLGYGLYTKARINSLTGKPMPTNPGGSDALMRE
ILKMKGVDFEIDSLSLQSLSGESNQIPSSVQYSWNPKQFNRKLVVGNRVLNSPG

Download         Length: 405 bp

>AT42964 NZ_AP027050:954223-954627 [Vibrio nigripulchritudo]
ATGACAGCAGTTGATCGTGTTTATCAAAAGATAAAGCGTTCCAGACGCTATGTTTTTGAGCGCAAAGACTTTGATGGTTT
TGCCAGCTACGACCAAATTGGTCGAGCGCTAAGGCAGTTGGTCAAACAAGGTGAGTTAATAAAGCTTGGCTATGGTCTCT
ACACCAAGGCAAGGATTAACAGTTTAACAGGCAAACCTATGCCCACTAACCCCGGTGGAAGCGATGCTCTTATGCGTGAG
ATTTTAAAGATGAAAGGCGTCGATTTTGAGATAGACAGCCTATCTTTGCAAAGCCTGTCCGGTGAAAGCAACCAAATTCC
ATCATCCGTTCAATACTCGTGGAACCCCAAACAGTTTAATCGCAAATTGGTTGTCGGTAACCGAGTATTAAATTCGCCAG
GCTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References