Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /GNAT-DUF1778
Location 311310..312226 Replicon plasmid pTUMSAT-V.nig1-1
Accession NZ_AP027047
Organism Vibrio nigripulchritudo strain TUMSAT-V.nig1

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag QMG95_RS29960 Protein ID WP_200768880.1
Coordinates 311310..311858 (-) Length 183 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag QMG95_RS29965 Protein ID WP_225911884.1
Coordinates 311855..312226 (-) Length 124 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QMG95_RS29920 (TUMSATVNIG1_59040) 307087..307254 - 168 WP_200768877.1 hypothetical protein -
QMG95_RS29925 (TUMSATVNIG1_59050) 307484..308119 - 636 WP_225911881.1 hypothetical protein -
QMG95_RS29930 (TUMSATVNIG1_59060) 308202..308816 - 615 WP_225911882.1 ABC transporter substrate-binding protein -
QMG95_RS29935 308761..309246 - 486 WP_225911883.1 SgrR family transcriptional regulator -
QMG95_RS29940 309348..309473 - 126 WP_263974337.1 hypothetical protein -
QMG95_RS29945 309699..310133 + 435 Protein_282 GrpB family protein -
QMG95_RS29950 (TUMSATVNIG1_59080) 310532..311032 + 501 WP_200768878.1 hypothetical protein -
QMG95_RS29955 311115..311270 - 156 WP_200768879.1 hypothetical protein -
QMG95_RS29960 (TUMSATVNIG1_59090) 311310..311858 - 549 WP_200768880.1 GNAT family N-acetyltransferase Toxin
QMG95_RS29965 (TUMSATVNIG1_59100) 311855..312226 - 372 WP_225911884.1 DUF1778 domain-containing protein Antitoxin
QMG95_RS29970 (TUMSATVNIG1_59110) 312523..312708 + 186 WP_200769027.1 hypothetical protein -
QMG95_RS29975 (TUMSATVNIG1_59120) 312720..313061 + 342 WP_200768882.1 endonuclease -
QMG95_RS29980 (TUMSATVNIG1_59130) 313480..314196 - 717 WP_022614092.1 RES domain-containing protein -
QMG95_RS29985 (TUMSATVNIG1_59140) 314193..315158 - 966 WP_052189099.1 hypothetical protein -
QMG95_RS29990 315459..315680 - 222 Protein_291 MepB family protein -
QMG95_RS29995 (TUMSATVNIG1_59160) 316475..317167 + 693 WP_200768884.1 Imm43 family immunity protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..351696 351696


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(97-153)

Antitoxin

Vibrio phage ICP1, Orf50

(36-115)


Sequences

Toxin        


Download         Length: 183 a.a.        Molecular weight: 20627.94 Da        Isoelectric Point: 9.1711

>T42962 WP_200768880.1 NZ_AP027047:c311858-311310 [Vibrio nigripulchritudo]
VSCGKEFVELSKSYHDRNSFDCGEQELNTFIKTQAAKHMEAGISRTMILPSTQPLLNQKIAICAFYSVAPSSISRETLPA
QLAKKLPRYPIPVFLLAQLAVHKEFQGSGLGKVSLVRALKYLWEVSHHMRAYAIVVDCLTDSAQAFYAKFGFEVLCEHNG
RIRMFLPMKTVERLFNQRENNN

Download         Length: 549 bp

>T42962 NZ_AP027047:c311858-311310 [Vibrio nigripulchritudo]
GTGAGTTGTGGTAAAGAGTTTGTAGAACTTAGTAAATCATATCACGACCGAAATTCATTCGATTGTGGTGAGCAAGAGCT
AAATACATTCATCAAAACTCAAGCAGCAAAGCATATGGAAGCAGGTATTAGTCGAACAATGATTCTTCCTAGTACTCAGC
CATTGCTTAATCAGAAGATTGCAATATGTGCATTTTACAGTGTTGCGCCTAGTTCAATCAGTCGAGAAACCTTACCAGCG
CAACTAGCAAAGAAACTTCCTCGATACCCCATTCCAGTGTTTCTTTTAGCTCAGTTAGCTGTGCATAAGGAATTTCAGGG
CTCTGGGCTAGGAAAAGTCAGTTTAGTCCGTGCACTAAAGTACCTTTGGGAAGTTAGCCACCATATGAGGGCGTATGCTA
TTGTCGTGGACTGTCTGACTGATTCAGCACAGGCGTTTTATGCAAAATTTGGCTTTGAAGTATTGTGTGAACATAATGGA
CGCATTCGCATGTTTCTACCAATGAAAACAGTAGAAAGACTTTTTAACCAACGAGAAAATAATAATTAG

Antitoxin


Download         Length: 124 a.a.        Molecular weight: 13816.89 Da        Isoelectric Point: 4.7814

>AT42962 WP_225911884.1 NZ_AP027047:c312226-311855 [Vibrio nigripulchritudo]
MHFIIRNLSVQVECVQCLNYNLWRYGICPYTGGFMATARLDIRLDEEIKAKAEKASALLGLKSLTEYVVRLMDEDATHVI
EEHESIVVKDSAFDEFMAACDKAKAPNQALLEAAKFTDESGIK

Download         Length: 372 bp

>AT42962 NZ_AP027047:c312226-311855 [Vibrio nigripulchritudo]
ATGCATTTTATTATCCGTAACCTTTCCGTACAAGTTGAATGTGTTCAATGTTTAAACTATAATCTCTGGCGTTACGGAAT
ATGTCCGTACACTGGAGGATTTATGGCAACAGCACGTTTAGATATCCGCCTTGATGAAGAGATAAAAGCGAAAGCTGAAA
AGGCATCAGCATTACTTGGTCTGAAAAGTTTAACTGAATATGTAGTTAGGCTTATGGACGAAGATGCAACACACGTAATT
GAAGAGCACGAAAGTATCGTGGTTAAGGATAGTGCCTTTGACGAATTTATGGCGGCTTGTGACAAAGCAAAAGCGCCTAA
TCAAGCTTTGTTGGAAGCTGCAAAATTCACAGATGAGAGCGGTATCAAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References