Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 283845..284380 Replicon plasmid pTUMSAT-V.nig1-1
Accession NZ_AP027047
Organism Vibrio nigripulchritudo strain TUMSAT-V.nig1

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag QMG95_RS29815 Protein ID WP_200768858.1
Coordinates 283845..284120 (-) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag QMG95_RS29820 Protein ID WP_200768859.1
Coordinates 284120..284380 (-) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QMG95_RS29800 (TUMSATVNIG1_58760) 279678..281405 - 1728 WP_200768857.1 AAA domain-containing protein -
QMG95_RS29805 282212..283227 + 1016 Protein_254 IS3 family transposase -
QMG95_RS29810 (TUMSATVNIG1_58790) 283537..283794 - 258 WP_225911879.1 hypothetical protein -
QMG95_RS29815 (TUMSATVNIG1_58800) 283845..284120 - 276 WP_200768858.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
QMG95_RS29820 (TUMSATVNIG1_58810) 284120..284380 - 261 WP_200768859.1 ribbon-helix-helix domain-containing protein Antitoxin
QMG95_RS29825 (TUMSATVNIG1_58820) 284585..285121 + 537 WP_200768860.1 recombinase family protein -
QMG95_RS29830 285142..288018 + 2877 Protein_259 Tn3 family transposase -
QMG95_RS29835 288409..288930 - 522 WP_200768861.1 AraC family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..351696 351696
- inside IScluster/Tn - - 268317..288018 19701


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-90)

Antitoxin

Ribbon-helix-helix protein, CopG

(6-41)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10718.34 Da        Isoelectric Point: 8.4198

>T42961 WP_200768858.1 NZ_AP027047:c284120-283845 [Vibrio nigripulchritudo]
MEIKWTSKALSDLSRLYEFLALADAIAAAKTVRSLTSAPDILSDQPRLGERLDAFEPREVRRLLVGSYEMRYEIQEYTLY
VLRIWHTREKR

Download         Length: 276 bp

>T42961 NZ_AP027047:c284120-283845 [Vibrio nigripulchritudo]
ATGGAAATAAAATGGACCAGTAAAGCCCTTTCCGATTTAAGCCGACTCTATGAATTCCTTGCCCTCGCAGATGCCATCGC
TGCGGCAAAGACAGTTCGCTCATTGACCAGTGCGCCTGACATACTGTCAGATCAGCCAAGACTGGGGGAGCGGCTTGATG
CTTTTGAGCCCAGGGAAGTTCGCAGGCTTTTGGTTGGCAGCTATGAAATGCGATATGAAATACAGGAATATACCCTGTAT
GTGCTTCGTATCTGGCATACGCGAGAGAAGCGCTAA

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9730.01 Da        Isoelectric Point: 5.1408

>AT42961 WP_200768859.1 NZ_AP027047:c284380-284120 [Vibrio nigripulchritudo]
MNTKVVTAHVPLQLADKVDELAQRLERSKAWVVKQALADWVVMEEERHKLTLEALADVDNDRVTDHQSVKAWAESLGSES
PKDVPR

Download         Length: 261 bp

>AT42961 NZ_AP027047:c284380-284120 [Vibrio nigripulchritudo]
ATGAATACCAAGGTTGTCACTGCACATGTTCCTTTGCAGCTAGCTGATAAAGTTGATGAGTTAGCACAGCGTCTCGAACG
CTCTAAAGCCTGGGTTGTCAAACAGGCTCTGGCGGATTGGGTCGTCATGGAAGAAGAGCGTCATAAACTGACACTGGAAG
CGTTGGCTGATGTTGACAATGACCGGGTTACTGATCACCAGTCTGTTAAGGCCTGGGCAGAAAGTTTGGGGAGTGAGTCT
CCCAAGGACGTGCCAAGGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References