Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vagCD/VapC-VagC
Location 159071..159719 Replicon plasmid pTUMSAT-V.nig1-1
Accession NZ_AP027047
Organism Vibrio nigripulchritudo strain TUMSAT-V.nig1

Toxin (Protein)


Gene name vagD Uniprot ID -
Locus tag QMG95_RS29255 Protein ID WP_200769018.1
Coordinates 159318..159719 (+) Length 134 a.a.

Antitoxin (Protein)


Gene name vagC Uniprot ID -
Locus tag QMG95_RS29250 Protein ID WP_200768999.1
Coordinates 159071..159304 (+) Length 78 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QMG95_RS29225 (TUMSATVNIG1_57600) 154519..155067 + 549 WP_200768995.1 hypothetical protein -
QMG95_RS29230 (TUMSATVNIG1_57610) 155064..155462 + 399 WP_200768996.1 hypothetical protein -
QMG95_RS29235 (TUMSATVNIG1_57620) 155825..156481 - 657 WP_281884297.1 hypothetical protein -
QMG95_RS29240 (TUMSATVNIG1_57630) 156697..157377 + 681 WP_200768998.1 hypothetical protein -
QMG95_RS29245 (TUMSATVNIG1_57640) 157408..158760 + 1353 WP_200769017.1 M66 family metalloprotease -
QMG95_RS29250 (TUMSATVNIG1_57650) 159071..159304 + 234 WP_200768999.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
QMG95_RS29255 (TUMSATVNIG1_57660) 159318..159719 + 402 WP_200769018.1 type II toxin-antitoxin system VapC family toxin Toxin
QMG95_RS29260 (TUMSATVNIG1_57670) 159733..159942 + 210 WP_200769000.1 hypothetical protein -
QMG95_RS29265 160076..161305 - 1230 WP_200769001.1 MFS transporter -
QMG95_RS29270 (TUMSATVNIG1_57700) 161580..162164 - 585 Protein_147 reverse transcriptase domain-containing protein -
QMG95_RS29275 (TUMSATVNIG1_57710) 163127..163477 + 351 WP_200769002.1 helix-turn-helix transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..351696 351696


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(1-124)

Antitoxin

SpoVT-AbrB domain

(7-54)


Sequences

Toxin        


Download         Length: 134 a.a.        Molecular weight: 14801.22 Da        Isoelectric Point: 7.8047

>T42959 WP_200769018.1 NZ_AP027047:159318-159719 [Vibrio nigripulchritudo]
MLDTCICSFIMREQPITVLQKLQSVVGKQHRIVISAITYQEMQYGLLGKKASPKHAVLVAEFLKRVDEILPWDKAAVDAT
TEVKRDLMARGAPIGNNDTAIAGHAIATGCVLVTNNTREFQRVDSLKLEDWVH

Download         Length: 402 bp

>T42959 NZ_AP027047:159318-159719 [Vibrio nigripulchritudo]
ATGCTAGATACGTGCATTTGCTCGTTCATCATGAGAGAGCAACCTATTACTGTGTTGCAAAAGCTTCAATCTGTGGTCGG
TAAGCAGCACAGGATTGTTATTTCCGCTATCACCTACCAAGAGATGCAATACGGGCTATTAGGCAAAAAGGCTTCTCCTA
AACACGCAGTGCTTGTTGCAGAATTTCTCAAGCGAGTTGATGAGATCTTACCTTGGGATAAAGCGGCAGTTGATGCGACT
ACAGAAGTTAAACGCGACCTAATGGCTAGAGGTGCACCTATTGGTAATAACGATACCGCTATCGCAGGTCATGCTATTGC
AACAGGGTGTGTTCTAGTAACGAACAACACAAGAGAGTTTCAGCGCGTAGACAGCTTAAAACTCGAAGACTGGGTTCATT
AA

Antitoxin


Download         Length: 78 a.a.        Molecular weight: 8934.89 Da        Isoelectric Point: 4.3217

>AT42959 WP_200768999.1 NZ_AP027047:159071-159304 [Vibrio nigripulchritudo]
MRTVSIFKNGKNQAVRLPKEFEFDGVNELEIHKEGDVITLRPARPDWLSFGEQNKADSDFMADREDVVTDEGRFDFE

Download         Length: 234 bp

>AT42959 NZ_AP027047:159071-159304 [Vibrio nigripulchritudo]
ATGAGAACGGTATCAATCTTTAAAAATGGGAAAAACCAAGCGGTTCGTCTGCCGAAAGAGTTTGAGTTCGACGGCGTGAA
CGAGCTGGAAATTCACAAAGAAGGAGACGTCATTACTTTACGACCAGCTAGACCAGACTGGTTGTCGTTTGGTGAGCAGA
ACAAGGCTGACAGCGATTTCATGGCTGATCGTGAAGATGTAGTGACAGATGAAGGGCGATTTGACTTTGAGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References