Detailed information of TA system TA042957

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/RelE-RelB
• Location: 2143212..2143771
• Replicon: chromosome
• Accession: NZ_AP027046
• Organism: Vibrio nigripulchritudo strain TUMSAT-V.nig1

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: QMG95_RS28455
• Protein ID: WP_200768106.1
• Coordinates: 2143493..2143771 (+)
• Length: 93 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: U4DQE1
• Locus tag: QMG95_RS28450
• Protein ID: WP_004404015.1
• Coordinates: 2143212..2143496 (+)
• Length: 95 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
QMG95_RS28430 (TUMSATVNIG1_55930)	2138817..2139851	+	1035	WP_200768102.1	iron ABC transporter permease	-
QMG95_RS28435 (TUMSATVNIG1_55940)	2139848..2140825	+	978	WP_200768103.1	iron chelate uptake ABC transporter family permease subunit	-
QMG95_RS28440 (TUMSATVNIG1_55950)	2140830..2141627	+	798	WP_200768104.1	ATP-binding cassette domain-containing protein	-
QMG95_RS28445 (TUMSATVNIG1_55960)	2141874..2142707	+	834	WP_200768105.1	inositol monophosphatase	-
QMG95_RS28450 (TUMSATVNIG1_55970)	2143212..2143496	+	285	WP_004404015.1	type II toxin-antitoxin system RelB/DinJ family antitoxin	Antitoxin
QMG95_RS28455 (TUMSATVNIG1_55980)	2143493..2143771	+	279	WP_200768106.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
QMG95_RS28460 (TUMSATVNIG1_55990)	2143821..2144105	-	285	Protein_1931	type II toxin-antitoxin system Phd/YefM family antitoxin	-
QMG95_RS28465	2144186..2144815	-	630	WP_225911873.1	DUF998 domain-containing protein	-
QMG95_RS28470 (TUMSATVNIG1_56000)	2144981..2145736	-	756	WP_200768108.1	uroporphyrinogen-III C-methyltransferase	-
QMG95_RS28475 (TUMSATVNIG1_56010)	2145789..2146598	-	810	WP_200768109.1	formate/nitrite transporter family protein	-
QMG95_RS28480 (TUMSATVNIG1_56020)	2146710..2147042	-	333	WP_200768110.1	nitrite reductase small subunit NirD	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (2-89)

Antitoxin

• RelB antitoxin/Antitoxin DinJ (5-72)

Sequences

Toxin

Protein

• Length: 93 a.a.
• Molecular weight: 10823.51 Da
• Isoelectric Point: 4.4290

>T42957 WP_200768106.1 NZ_AP027046:2143493-2143771 [Vibrio nigripulchritudo]
MILWEEESLNDREKIFEFLYDFNPDAAEKTDSLIEAKVENLLEQPLMGVQRNGIRGRLLIIPEVSIIVPYWVEGDIIRVL
RVLHQKQKFPTD

Nucleotide

• Length: 279 bp

>T42957 NZ_AP027046:2143493-2143771 [Vibrio nigripulchritudo]
ATGATTTTATGGGAAGAAGAGTCACTTAATGATCGTGAAAAGATCTTTGAGTTTCTCTATGACTTCAATCCTGATGCAGC
AGAGAAAACCGACAGCCTCATTGAAGCAAAAGTAGAAAACTTGCTTGAGCAACCTCTTATGGGCGTGCAAAGAAACGGAA
TCCGTGGACGTTTACTCATTATTCCTGAGGTATCAATAATCGTACCGTACTGGGTTGAAGGCGATATTATCCGCGTTTTG
CGTGTGCTCCACCAAAAACAAAAATTCCCTACGGATTGA

Antitoxin

Protein

• Length: 95 a.a.
• Molecular weight: 11022.34 Da
• Isoelectric Point: 8.0517

>AT42957 WP_004404015.1 NZ_AP027046:2143212-2143496 [Vibrio nigripulchritudo]
MDTRIQFRVDEETKRLAQQMAESQGRTLSDACRELTEQLAEQQRKTLSHDAWLTEQVNLAFEKLDSGKSVFVEHESAKSR
MEERKARIRNRGKQ

Nucleotide

• Length: 285 bp

>AT42957 NZ_AP027046:2143212-2143496 [Vibrio nigripulchritudo]
ATGGACACTAGAATTCAGTTTCGTGTTGATGAGGAAACAAAACGCTTAGCTCAGCAAATGGCTGAAAGCCAGGGTCGTAC
ATTGAGTGATGCTTGCCGAGAACTTACTGAACAACTCGCTGAACAACAAAGAAAAACACTGTCTCACGATGCATGGCTAA
CTGAACAAGTAAACCTAGCATTTGAGAAGCTTGACTCAGGAAAATCGGTTTTCGTTGAACATGAATCGGCTAAATCTCGA
ATGGAAGAACGCAAAGCCAGAATCCGTAACCGAGGTAAGCAATGA

Structures

Antitoxin

• AlphaFold DB: U4DQE1