Detailed information of TA system TA042956

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): slvAT/RES(toxin)
• Location: 3762541..3763463
• Replicon: chromosome
• Accession: NZ_AP027041
• Organism: Lysobacter auxotrophicus strain 5-21a

Toxin (Protein)

• Gene name: slvT
• Uniprot ID: -
• Locus tag: LA521A_RS17125
• Protein ID: WP_281780048.1
• Coordinates: 3762918..3763463 (+)
• Length: 182 a.a.

Antitoxin (Protein)

• Gene name: slvA
• Uniprot ID: -
• Locus tag: LA521A_RS17120
• Protein ID: WP_281780047.1
• Coordinates: 3762541..3762921 (+)
• Length: 127 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
LA521A_RS17100 (LA521A_33700)	3758030..3758962	-	933	WP_281780043.1	S41 family peptidase	-
LA521A_RS17105 (LA521A_33710)	3759056..3759409	+	354	WP_281780044.1	6-carboxytetrahydropterin synthase QueD	-
LA521A_RS17110 (LA521A_33720)	3759450..3761741	-	2292	WP_281780045.1	patatin-like phospholipase family protein	-
LA521A_RS17115 (LA521A_33730)	3761758..3762345	+	588	WP_281780046.1	phasin family protein	-
LA521A_RS17120 (LA521A_33740)	3762541..3762921	+	381	WP_281780047.1	hypothetical protein	Antitoxin
LA521A_RS17125 (LA521A_33750)	3762918..3763463	+	546	WP_281780048.1	RES domain-containing protein	Toxin
LA521A_RS17130 (LA521A_33760)	3763585..3763992	+	408	WP_281780049.1	inner membrane protein YiaA	-
LA521A_RS17135 (LA521A_33770)	3764051..3767218	-	3168	WP_281780050.1	multidrug efflux RND transporter permease subunit	-
LA521A_RS17140 (LA521A_33780)	3767228..3768448	-	1221	WP_281780051.1	efflux RND transporter periplasmic adaptor subunit	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• RES domain (12-167)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 182 a.a.
• Molecular weight: 19905.42 Da
• Isoelectric Point: 5.2515

>T42956 WP_281780048.1 NZ_AP027041:3762918-3763463 [Lysobacter auxotrophicus]
MILRTLGDGDALYRVIVPRWSHAPTSGAGAARKGGRFNRPGLEALYLSKDAITAVEEYRQHERLLPPGTLVTFLVGPLTV
VDFAGGFESGRWEPIWADYACNWRRLAFDERSEPPSWVLGDLALDAGAAGILFPSSVHAGGTNLVLFDSSQLPARMLRVH
DPDHRLPDDARSWLDADDARD

Nucleotide

• Length: 546 bp

>T42956 NZ_AP027041:3762918-3763463 [Lysobacter auxotrophicus]
ATGATCCTGCGCACGCTGGGCGATGGCGACGCGCTGTACCGCGTCATCGTCCCGCGCTGGTCGCATGCGCCCACGTCCGG
CGCGGGCGCGGCGCGCAAGGGCGGGCGCTTCAACCGGCCGGGCCTGGAAGCGCTGTACCTGTCGAAGGACGCCATCACCG
CGGTGGAGGAATACCGCCAGCACGAACGGCTGCTGCCGCCGGGCACGCTGGTGACGTTCCTCGTCGGGCCGCTGACGGTG
GTCGATTTCGCCGGCGGTTTCGAAAGCGGTCGCTGGGAGCCGATCTGGGCCGATTACGCCTGCAACTGGCGCCGCCTCGC
CTTCGACGAACGCAGCGAACCGCCGAGCTGGGTGCTCGGCGACTTGGCGCTGGATGCGGGCGCCGCCGGGATTCTCTTTC
CGTCATCCGTCCATGCCGGCGGCACCAACCTGGTGTTGTTCGATTCGAGCCAGCTGCCCGCGCGAATGCTGCGCGTACAC
GATCCCGACCATCGCCTGCCCGACGACGCGCGTTCGTGGCTCGACGCGGACGACGCGCGCGACTGA

Antitoxin

Protein

• Length: 127 a.a.
• Molecular weight: 13798.59 Da
• Isoelectric Point: 5.1634

>AT42956 WP_281780047.1 NZ_AP027041:3762541-3762921 [Lysobacter auxotrophicus]
MNAVMKPRASLAETLREPDQVYLSPRRIGDALGLQVQSLAERARVSRNTPTARPQNEHLQQYLRDVVRVIAAAEDAAGGD
RTRAIFWFMNDPLAEFDYLTADALVQAGKAQVVIDYIESIAGGATG

Nucleotide

• Length: 381 bp

>AT42956 NZ_AP027041:3762541-3762921 [Lysobacter auxotrophicus]
ATGAACGCCGTCATGAAACCCCGTGCGAGCCTCGCCGAGACCCTGCGCGAGCCCGACCAGGTCTACCTCTCGCCGCGCCG
CATTGGCGATGCGCTCGGCCTGCAGGTCCAGAGCCTGGCCGAACGCGCCCGGGTCAGCCGCAACACGCCGACCGCGCGCC
CGCAGAACGAACACCTCCAGCAATACCTGCGCGACGTCGTGCGCGTCATCGCCGCTGCCGAAGATGCCGCCGGTGGCGAT
CGCACGCGCGCCATCTTCTGGTTCATGAACGATCCGCTGGCCGAATTCGACTACCTCACCGCCGACGCACTGGTGCAGGC
GGGCAAGGCGCAGGTCGTGATCGACTACATCGAGTCGATCGCCGGCGGCGCCACCGGATGA