Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 254124..254395 Replicon chromosome
Accession NZ_AP026937
Organism Escherichia coli strain EC20-4B-2

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 254254..254357 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 254124..254395 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OO845_RS01255 250679..251341 - 663 WP_000944256.1 exodeoxyribonuclease X -
OO845_RS01260 251365..252021 - 657 WP_000011652.1 carbon-nitrogen hydrolase family protein YobB -
OO845_RS01265 252123..252353 - 231 WP_000916763.1 DNA polymerase III subunit theta -
OO845_RS01270 252492..252866 + 375 WP_000204699.1 CopC domain-containing protein YobA -
OO845_RS01275 252870..253742 + 873 WP_000879282.1 copper homeostasis membrane protein CopD -
OO845_RS01280 253755..254096 + 342 WP_000976472.1 YebY family protein -
- 254124..254395 - 272 - - Antitoxin
- 254254..254357 + 104 - - Toxin
OO845_RS01285 254492..255148 + 657 WP_000812724.1 protein-serine/threonine phosphatase -
OO845_RS01290 255161..255340 - 180 WP_089644822.1 YebW family protein -
OO845_RS01295 255445..255681 - 237 WP_001295499.1 YebV family protein -
OO845_RS01300 255799..257238 - 1440 WP_001307251.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T42879 NZ_AP026937:254254-254357 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT42879 NZ_AP026937:c254395-254124 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References