42860

Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1867977..1868122 Replicon chromosome
Accession NZ_AP026913
Organism Klebsiella pneumoniae strain Kp21r_f22

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1868013..1868115 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1867977..1868122 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
kp21f22_RS09095 1863107..1865167 + 2061 WP_004151449.1 oligopeptidase B -
kp21f22_RS09100 1865171..1865830 - 660 WP_002911407.1 exodeoxyribonuclease X -
kp21f22_RS09105 1865909..1866139 - 231 WP_002911406.1 DNA polymerase III subunit theta -
kp21f22_RS09110 1866252..1866626 + 375 WP_004151448.1 CopC domain-containing protein YobA -
kp21f22_RS09115 1866630..1867499 + 870 WP_004189267.1 copper homeostasis membrane protein CopD -
kp21f22_RS09120 1867516..1867854 + 339 WP_002911404.1 YebY family protein -
- 1867977..1868122 - 146 - - Antitoxin
- 1868013..1868115 + 103 - - Toxin
kp21f22_RS09125 1868490..1868633 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
kp21f22_RS09130 1868738..1869706 - 969 WP_004151446.1 VirK/YbjX family protein -
kp21f22_RS09135 1869863..1870516 + 654 WP_264839187.1 protein-serine/threonine phosphatase -
kp21f22_RS09140 1870513..1870704 - 192 WP_002911395.1 YebW family protein -
kp21f22_RS09145 1870802..1871041 - 240 WP_002911393.1 YebV family protein -
kp21f22_RS09150 1871157..1872590 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T42860 NZ_AP026913:1868013-1868115 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT42860 NZ_AP026913:c1868122-1867977 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References