Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1867976..1868121 Replicon chromosome
Accession NZ_AP026912
Organism Klebsiella pneumoniae strain Kp21_f22

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1868012..1868114 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1867976..1868121 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OO849_RS09090 1863106..1865166 + 2061 WP_004151449.1 oligopeptidase B -
OO849_RS09095 1865170..1865829 - 660 WP_002911407.1 exodeoxyribonuclease X -
OO849_RS09100 1865908..1866138 - 231 WP_002911406.1 DNA polymerase III subunit theta -
OO849_RS09105 1866251..1866625 + 375 WP_004151448.1 CopC domain-containing protein YobA -
OO849_RS09110 1866629..1867498 + 870 WP_004189267.1 copper homeostasis membrane protein CopD -
OO849_RS09115 1867515..1867853 + 339 WP_002911404.1 YebY family protein -
- 1867976..1868121 - 146 - - Antitoxin
- 1868012..1868114 + 103 - - Toxin
OO849_RS09120 1868489..1868632 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
OO849_RS09125 1868737..1869705 - 969 WP_004151446.1 VirK/YbjX family protein -
OO849_RS09130 1869862..1870515 + 654 WP_264839187.1 protein-serine/threonine phosphatase -
OO849_RS09135 1870512..1870703 - 192 WP_002911395.1 YebW family protein -
OO849_RS09140 1870801..1871040 - 240 WP_002911393.1 YebV family protein -
OO849_RS09145 1871156..1872589 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T42840 NZ_AP026912:1868012-1868114 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT42840 NZ_AP026912:c1868121-1867976 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References