Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | ataT-KacA/DUF1778(antitoxin) |
| Location | 1659307..1660104 | Replicon | chromosome |
| Accession | NZ_AP026873 | ||
| Organism | Enterobacter roggenkampii strain KAM546 | ||
Toxin (Protein)
| Gene name | ataT | Uniprot ID | - |
| Locus tag | OO938_RS08090 | Protein ID | WP_063417750.1 |
| Coordinates | 1659583..1660104 (+) | Length | 174 a.a. |
Antitoxin (Protein)
| Gene name | KacA | Uniprot ID | W7PG43 |
| Locus tag | OO938_RS08085 | Protein ID | WP_008499829.1 |
| Coordinates | 1659307..1659576 (+) | Length | 90 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| OO938_RS08055 (KAM546c_15900) | 1654930..1655373 | - | 444 | WP_008499834.1 | helix-turn-helix domain-containing protein | - |
| OO938_RS08060 (KAM546c_15910) | 1655526..1656767 | + | 1242 | WP_252076261.1 | bifunctional glucose-1-phosphatase/inositol phosphatase | - |
| OO938_RS08065 (KAM546c_15920) | 1656803..1657030 | - | 228 | WP_008499832.1 | YccJ family protein | - |
| OO938_RS08070 (KAM546c_15930) | 1657051..1657647 | - | 597 | WP_008499831.1 | NAD(P)H:quinone oxidoreductase | - |
| OO938_RS08075 (KAM546c_15940) | 1658039..1658209 | + | 171 | WP_013097201.1 | general stress protein | - |
| OO938_RS08080 (KAM546c_15950) | 1658328..1659245 | + | 918 | WP_220419920.1 | DMT family transporter | - |
| OO938_RS08085 (KAM546c_15960) | 1659307..1659576 | + | 270 | WP_008499829.1 | DUF1778 domain-containing protein | Antitoxin |
| OO938_RS08090 (KAM546c_15970) | 1659583..1660104 | + | 522 | WP_063417750.1 | GNAT family N-acetyltransferase | Toxin |
| OO938_RS08095 (KAM546c_15980) | 1660178..1661500 | - | 1323 | WP_264883065.1 | pyrimidine utilization transport protein G | - |
| OO938_RS08100 (KAM546c_15990) | 1661522..1662016 | - | 495 | WP_023292823.1 | pyrimidine utilization flavin reductase protein F | - |
| OO938_RS08105 (KAM546c_16000) | 1662026..1662616 | - | 591 | WP_248224774.1 | malonic semialdehyde reductase | - |
| OO938_RS08110 (KAM546c_16010) | 1662626..1663426 | - | 801 | WP_177317295.1 | pyrimidine utilization protein D | - |
| OO938_RS08115 (KAM546c_16020) | 1663434..1663820 | - | 387 | WP_264883070.1 | pyrimidine utilization protein C | - |
| OO938_RS08120 (KAM546c_16030) | 1663832..1664521 | - | 690 | WP_264883072.1 | pyrimidine utilization protein B | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 174 a.a. Molecular weight: 19656.42 Da Isoelectric Point: 7.4313
>T42773 WP_063417750.1 NZ_AP026873:1659583-1660104 [Enterobacter roggenkampii]
VDNLTIEMFSEGKDYDFRDFDCGEPSLNVFLTEHLVRQHNGRILRGYLLKDRDGPRVLGYYTLSGSCFEKAMLPSKTQQR
RIPYSNVPSVTLGRLAIHKDLQGLEWGTTLVTHAMRVVYLASQAVGVHGIFVDALNDQAKQFYLKQGFIPLTGENSHSLF
FPTKSIERLFEQA
VDNLTIEMFSEGKDYDFRDFDCGEPSLNVFLTEHLVRQHNGRILRGYLLKDRDGPRVLGYYTLSGSCFEKAMLPSKTQQR
RIPYSNVPSVTLGRLAIHKDLQGLEWGTTLVTHAMRVVYLASQAVGVHGIFVDALNDQAKQFYLKQGFIPLTGENSHSLF
FPTKSIERLFEQA
Download Length: 522 bp
>T42773 NZ_AP026873:1659583-1660104 [Enterobacter roggenkampii]
GTGGACAATCTCACGATCGAAATGTTTTCAGAGGGAAAAGACTATGATTTCAGGGACTTCGATTGTGGTGAACCCTCGCT
AAATGTCTTCCTCACAGAACATCTGGTGCGTCAGCACAATGGGCGTATTTTACGAGGCTATTTGCTTAAAGATCGCGATG
GTCCGCGAGTCCTGGGCTATTACACGTTGTCTGGTAGTTGCTTTGAAAAAGCGATGCTGCCTTCTAAGACTCAGCAGCGT
CGAATCCCTTATAGCAACGTACCGAGCGTAACGCTGGGGCGCCTGGCGATACATAAAGACTTACAGGGGCTGGAGTGGGG
AACGACGCTCGTCACGCATGCCATGCGGGTTGTCTATCTGGCATCGCAGGCGGTGGGTGTACACGGAATATTTGTTGATG
CACTCAACGACCAGGCAAAACAATTTTATCTGAAGCAGGGCTTTATTCCGCTGACGGGTGAAAACAGCCATTCTCTTTTC
TTTCCTACAAAATCTATCGAACGACTGTTTGAGCAGGCGTGA
GTGGACAATCTCACGATCGAAATGTTTTCAGAGGGAAAAGACTATGATTTCAGGGACTTCGATTGTGGTGAACCCTCGCT
AAATGTCTTCCTCACAGAACATCTGGTGCGTCAGCACAATGGGCGTATTTTACGAGGCTATTTGCTTAAAGATCGCGATG
GTCCGCGAGTCCTGGGCTATTACACGTTGTCTGGTAGTTGCTTTGAAAAAGCGATGCTGCCTTCTAAGACTCAGCAGCGT
CGAATCCCTTATAGCAACGTACCGAGCGTAACGCTGGGGCGCCTGGCGATACATAAAGACTTACAGGGGCTGGAGTGGGG
AACGACGCTCGTCACGCATGCCATGCGGGTTGTCTATCTGGCATCGCAGGCGGTGGGTGTACACGGAATATTTGTTGATG
CACTCAACGACCAGGCAAAACAATTTTATCTGAAGCAGGGCTTTATTCCGCTGACGGGTGAAAACAGCCATTCTCTTTTC
TTTCCTACAAAATCTATCGAACGACTGTTTGAGCAGGCGTGA
Antitoxin
Download Length: 90 a.a. Molecular weight: 10262.72 Da Isoelectric Point: 5.8836
>AT42773 WP_008499829.1 NZ_AP026873:1659307-1659576 [Enterobacter roggenkampii]
MPALKKQRIDLRLTDEDKTMIEEAAAMTNQTITQFMVNSASERAAEVIEQHRRLVLNEASWNAVMDAIDNPPEPNERLKR
AAKRLRNME
MPALKKQRIDLRLTDEDKTMIEEAAAMTNQTITQFMVNSASERAAEVIEQHRRLVLNEASWNAVMDAIDNPPEPNERLKR
AAKRLRNME
Download Length: 270 bp
>AT42773 NZ_AP026873:1659307-1659576 [Enterobacter roggenkampii]
ATGCCAGCACTGAAAAAACAGCGTATCGATCTTCGCTTAACGGACGAAGATAAAACAATGATTGAAGAAGCGGCAGCGAT
GACGAATCAAACGATCACCCAGTTTATGGTGAACAGTGCGTCAGAGCGGGCAGCGGAAGTCATCGAGCAGCACCGCCGTC
TCGTATTAAACGAAGCATCCTGGAATGCGGTGATGGATGCCATCGACAATCCACCAGAGCCAAATGAACGCCTGAAGCGA
GCGGCGAAACGTCTTCGAAACATGGAGTGA
ATGCCAGCACTGAAAAAACAGCGTATCGATCTTCGCTTAACGGACGAAGATAAAACAATGATTGAAGAAGCGGCAGCGAT
GACGAATCAAACGATCACCCAGTTTATGGTGAACAGTGCGTCAGAGCGGGCAGCGGAAGTCATCGAGCAGCACCGCCGTC
TCGTATTAAACGAAGCATCCTGGAATGCGGTGATGGATGCCATCGACAATCCACCAGAGCCAAATGAACGCCTGAAGCGA
GCGGCGAAACGTCTTCGAAACATGGAGTGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|