Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | vapBC/PIN-AbrB |
| Location | 897412..898022 | Replicon | chromosome |
| Accession | NZ_AP026830 | ||
| Organism | Vulcanisaeta souniana JCM 11219 strain IC-059 | ||
Toxin (Protein)
| Gene name | vapC | Uniprot ID | A0A830ECQ0 |
| Locus tag | Vsou_RS04785 | Protein ID | WP_054843244.1 |
| Coordinates | 897412..897789 (-) | Length | 126 a.a. |
Antitoxin (Protein)
| Gene name | vapB | Uniprot ID | - |
| Locus tag | Vsou_RS04790 | Protein ID | WP_188602418.1 |
| Coordinates | 897792..898022 (-) | Length | 77 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| Vsou_RS04735 (Vsou_09500) | 892739..892897 | - | 159 | WP_229709682.1 | hypothetical protein | - |
| Vsou_RS04740 (Vsou_09510) | 893010..893153 | - | 144 | WP_188602424.1 | hypothetical protein | - |
| Vsou_RS04745 (Vsou_09520) | 893150..893368 | - | 219 | WP_054843249.1 | AbrB/MazE/SpoVT family DNA-binding domain-containing protein | - |
| Vsou_RS04750 (Vsou_09530) | 893670..894428 | + | 759 | WP_188602423.1 | nucleotidyltransferase domain-containing protein | - |
| Vsou_RS04755 (Vsou_09540) | 894450..894980 | + | 531 | WP_188602422.1 | PaREP1 family protein | - |
| Vsou_RS04760 (Vsou_09550) | 895050..895310 | + | 261 | WP_054843247.1 | AbrB/MazE/SpoVT family DNA-binding domain-containing protein | - |
| Vsou_RS04765 (Vsou_09570) | 895469..895834 | - | 366 | WP_188602420.1 | aspartyl protease family protein | - |
| Vsou_RS04770 (Vsou_09580) | 895878..896210 | - | 333 | WP_264890811.1 | hypothetical protein | - |
| Vsou_RS04775 (Vsou_09590) | 896179..896721 | - | 543 | WP_229709679.1 | ATP-binding protein | - |
| Vsou_RS04780 (Vsou_09600) | 896736..896873 | - | 138 | WP_229709678.1 | hypothetical protein | - |
| Vsou_RS04785 (Vsou_09620) | 897412..897789 | - | 378 | WP_054843244.1 | PIN domain-containing protein | Toxin |
| Vsou_RS04790 (Vsou_09630) | 897792..898022 | - | 231 | WP_188602418.1 | AbrB/MazE/SpoVT family DNA-binding domain-containing protein | Antitoxin |
| Vsou_RS04795 (Vsou_09640) | 898383..899126 | - | 744 | WP_188602417.1 | hypothetical protein | - |
| Vsou_RS04800 (Vsou_09650) | 899218..899586 | + | 369 | WP_188602416.1 | DNA-binding protein | - |
| Vsou_RS04805 (Vsou_09660) | 899751..900335 | - | 585 | WP_264890780.1 | DedA family protein | - |
| Vsou_RS04810 (Vsou_09670) | 900478..900768 | + | 291 | WP_054843242.1 | hypothetical protein | - |
| Vsou_RS04815 (Vsou_09680) | 900825..901268 | + | 444 | WP_054843241.1 | hypothetical protein | - |
| Vsou_RS04820 (Vsou_09690) | 901272..901847 | + | 576 | WP_188602414.1 | nucleotidyltransferase family protein | - |
| Vsou_RS04825 (Vsou_09700) | 901806..902258 | - | 453 | WP_188602413.1 | hypothetical protein | - |
| Vsou_RS04830 (Vsou_09710) | 902501..902719 | + | 219 | WP_054843238.1 | hypothetical protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 126 a.a. Molecular weight: 14502.59 Da Isoelectric Point: 4.4980
>T42768 WP_054843244.1 NZ_AP026830:c897789-897412 [Vulcanisaeta souniana JCM 11219]
MSFVVDTNFIVAVISEDDVSHDKAVSLWDSLNEAYVPIIVIAELSYFFIRHKIDVGIISEILRDSKIKVVENNVQDIYFA
IDHKDYIRHYDDFNDLIVLSTARRLGLPLITFDDELLDLYHKLKS
MSFVVDTNFIVAVISEDDVSHDKAVSLWDSLNEAYVPIIVIAELSYFFIRHKIDVGIISEILRDSKIKVVENNVQDIYFA
IDHKDYIRHYDDFNDLIVLSTARRLGLPLITFDDELLDLYHKLKS
Download Length: 378 bp
>T42768 NZ_AP026830:c897789-897412 [Vulcanisaeta souniana JCM 11219]
ATGAGCTTTGTAGTTGATACAAACTTTATAGTGGCTGTGATCTCCGAGGATGATGTGAGCCATGATAAGGCAGTAAGTCT
TTGGGATTCCCTAAATGAAGCTTACGTGCCAATAATTGTAATTGCCGAGTTAAGTTACTTCTTCATTAGGCATAAAATTG
ATGTGGGTATCATAAGTGAGATTCTACGGGACTCTAAGATTAAGGTTGTTGAAAATAATGTGCAGGATATATACTTTGCT
ATTGATCATAAAGATTACATTAGGCATTATGATGACTTTAACGACTTGATAGTGCTTAGCACGGCAAGAAGATTAGGCTT
ACCATTAATTACATTTGACGATGAACTGCTAGACCTCTACCATAAACTTAAGTCCTGA
ATGAGCTTTGTAGTTGATACAAACTTTATAGTGGCTGTGATCTCCGAGGATGATGTGAGCCATGATAAGGCAGTAAGTCT
TTGGGATTCCCTAAATGAAGCTTACGTGCCAATAATTGTAATTGCCGAGTTAAGTTACTTCTTCATTAGGCATAAAATTG
ATGTGGGTATCATAAGTGAGATTCTACGGGACTCTAAGATTAAGGTTGTTGAAAATAATGTGCAGGATATATACTTTGCT
ATTGATCATAAAGATTACATTAGGCATTATGATGACTTTAACGACTTGATAGTGCTTAGCACGGCAAGAAGATTAGGCTT
ACCATTAATTACATTTGACGATGAACTGCTAGACCTCTACCATAAACTTAAGTCCTGA
Antitoxin
Download Length: 77 a.a. Molecular weight: 9133.70 Da Isoelectric Point: 10.3666
>AT42768 WP_188602418.1 NZ_AP026830:c898022-897792 [Vulcanisaeta souniana JCM 11219]
MIDETKVTRNYQITIPASIRKRLGLRVGDTLIVRLEGERIILEPKRRSITEIRIRLGKKIDWRYVEETIREEIEKE
MIDETKVTRNYQITIPASIRKRLGLRVGDTLIVRLEGERIILEPKRRSITEIRIRLGKKIDWRYVEETIREEIEKE
Download Length: 231 bp
>AT42768 NZ_AP026830:c898022-897792 [Vulcanisaeta souniana JCM 11219]
ATGATTGATGAAACTAAGGTAACTAGGAATTATCAAATAACGATACCGGCGTCTATTAGGAAAAGGCTTGGTTTAAGGGT
TGGGGATACGCTCATAGTTAGGCTTGAGGGTGAGAGGATAATTCTTGAGCCAAAGAGACGAAGCATCACGGAAATAAGGA
TTAGGTTGGGGAAAAAAATAGATTGGAGGTATGTTGAGGAGACCATAAGGGAAGAGATTGAGAAGGAGTGA
ATGATTGATGAAACTAAGGTAACTAGGAATTATCAAATAACGATACCGGCGTCTATTAGGAAAAGGCTTGGTTTAAGGGT
TGGGGATACGCTCATAGTTAGGCTTGAGGGTGAGAGGATAATTCTTGAGCCAAAGAGACGAAGCATCACGGAAATAAGGA
TTAGGTTGGGGAAAAAAATAGATTGGAGGTATGTTGAGGAGACCATAAGGGAAGAGATTGAGAAGGAGTGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|