42656

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) sanaTA/AbiEii-DUF6088
Location 921835..923183 Replicon chromosome
Accession NZ_AP026781
Organism Photobacterium damselae subsp. damselae strain 04Ya311

Toxin (Protein)


Gene name sanaT Uniprot ID -
Locus tag OO966_RS18950 Protein ID WP_264955740.1
Coordinates 921835..922776 (-) Length 314 a.a.

Antitoxin (Protein)


Gene name sanaA Uniprot ID -
Locus tag OO966_RS18955 Protein ID WP_264955741.1
Coordinates 922779..923183 (-) Length 135 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OO966_RS18945 (PDY_35480) 917351..921394 - 4044 WP_264955739.1 hypothetical protein -
OO966_RS18950 (PDY_35500) 921835..922776 - 942 WP_264955740.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
OO966_RS18955 (PDY_35510) 922779..923183 - 405 WP_264955741.1 DUF6088 family protein Antitoxin
OO966_RS18960 (PDY_35520) 923503..923841 + 339 WP_086368146.1 cytosolic protein -
OO966_RS18965 (PDY_35530) 924104..924370 + 267 WP_036765517.1 hypothetical protein -
OO966_RS18970 (PDY_35540) 924409..924780 - 372 WP_264955742.1 MmcQ/YjbR family DNA-binding protein -
OO966_RS18975 (PDY_35550) 924906..925910 + 1005 WP_151182512.1 low-specificity L-threonine aldolase -
OO966_RS18980 (PDY_35560) 926112..926834 + 723 WP_264955743.1 SDR family NAD(P)-dependent oxidoreductase -
OO966_RS18985 (PDY_35570) 926860..927447 - 588 WP_264955744.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(37-300)

Antitoxin

Protein of unknown function DUF6088

(7-130)


Sequences

Toxin        


Download         Length: 314 a.a.        Molecular weight: 36205.70 Da        Isoelectric Point: 6.3966

>T42656 WP_264955740.1 NZ_AP026781:c922776-921835 [Photobacterium damselae subsp. damselae]
MNKLKQQFLEVSDALALGNPAIIEKDYWVVALLAQLEKLTIDSHQLVFSGGTALAKSNVKIMRMSEDVDIKLIPNADFHT
LSRSKKKTVRKLLIEILEKAIEESNTFSIEDKQAWDEYRYVEYDLKYPQQFSQAPCLRPIIKLELMETIPLQETEQRSIQ
SLVAELYRTKKEVKAFTCVSVHVTLVEKIISMLRRTMLAKRDENRKDDHTLVRHIYDVYCIDATQPIDIESLSPLFNAVL
QEDITRFGNQHDEFVNNPSKELQSGLSELEANSLYRQRFEAFVTPMVFNQQPHDFDTCFASFKRIAASLIKKI

Download         Length: 942 bp

>T42656 NZ_AP026781:c922776-921835 [Photobacterium damselae subsp. damselae]
ATGAATAAGCTGAAACAGCAGTTTCTTGAGGTTTCCGATGCTTTAGCGCTCGGAAACCCAGCTATCATTGAAAAAGATTA
TTGGGTTGTGGCACTGTTAGCGCAACTTGAAAAACTCACCATAGATTCTCATCAACTGGTCTTTTCTGGCGGTACTGCAT
TGGCAAAATCCAATGTGAAGATTATGCGTATGTCTGAAGATGTTGATATTAAGCTGATCCCTAATGCCGACTTTCATACA
TTAAGCAGAAGTAAGAAAAAAACTGTTCGTAAATTATTGATTGAGATACTTGAAAAAGCGATTGAAGAGTCAAATACCTT
TTCGATTGAAGATAAACAAGCATGGGACGAATACCGCTATGTGGAATATGACTTAAAATATCCACAGCAGTTTAGTCAAG
CACCTTGTTTACGCCCCATTATCAAACTTGAATTGATGGAAACCATTCCATTACAAGAAACAGAGCAGCGAAGCATACAA
TCCTTAGTAGCGGAACTTTACCGAACTAAGAAAGAAGTTAAAGCATTTACTTGTGTATCTGTTCATGTCACGTTAGTTGA
AAAGATCATTTCAATGCTTCGTCGTACCATGCTGGCTAAGCGTGATGAAAATCGTAAAGACGATCACACATTAGTGCGTC
ATATCTACGATGTTTACTGCATAGATGCAACACAACCAATTGATATTGAATCACTATCACCGCTCTTTAATGCAGTATTA
CAAGAAGATATCACTCGCTTTGGTAATCAACATGATGAATTTGTAAATAATCCATCTAAAGAGCTACAAAGTGGCTTATC
AGAATTAGAAGCTAATTCACTTTATCGCCAACGCTTTGAGGCTTTTGTCACTCCAATGGTTTTTAACCAACAACCTCACG
ATTTTGATACCTGCTTTGCCTCATTTAAACGCATTGCAGCATCGCTAATTAAAAAAATTTAA

Antitoxin


Download         Length: 135 a.a.        Molecular weight: 15298.70 Da        Isoelectric Point: 10.4940

>AT42656 WP_264955741.1 NZ_AP026781:c923183-922779 [Photobacterium damselae subsp. damselae]
MTTVDRIYQKIKRSRRYVFERKNFEGVACYDQVGRALKQLVNQGELMKIGYGLYTKSRMNSLTGKPMPTHPGGTDALMRE
ILKMKGVDFEIDSLSIQSLSGESTQIPSSIHYSWNLKQFNRKLVVGSRVIHSPN

Download         Length: 405 bp

>AT42656 NZ_AP026781:c923183-922779 [Photobacterium damselae subsp. damselae]
ATGACTACAGTTGATCGTATTTATCAAAAGATAAAACGTTCAAGACGTTATGTTTTTGAACGTAAAAACTTTGAAGGTGT
GGCTTGTTATGATCAAGTCGGTCGAGCTTTGAAACAATTAGTAAACCAAGGCGAATTAATGAAAATCGGCTATGGTCTTT
ACACCAAATCACGAATGAATAGTTTAACAGGTAAGCCAATGCCAACTCATCCAGGTGGGACGGACGCACTTATGCGAGAA
ATCCTTAAGATGAAAGGCGTAGACTTTGAGATAGATAGCCTGTCTATTCAAAGCTTATCGGGTGAAAGTACTCAAATTCC
TTCATCCATCCATTACTCATGGAACTTAAAACAGTTTAATCGAAAACTGGTAGTGGGTAGTCGTGTCATACACTCGCCAA
ATTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References