Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | relBE/RelE-RelB |
| Location | 1565298..1565857 | Replicon | chromosome |
| Accession | NZ_AP026765 | ||
| Organism | Vibrio sp. STUT-A16 | ||
Toxin (Protein)
| Gene name | relE | Uniprot ID | - |
| Locus tag | OO778_RS07335 | Protein ID | WP_264911205.1 |
| Coordinates | 1565298..1565576 (-) | Length | 93 a.a. |
Antitoxin (Protein)
| Gene name | relB | Uniprot ID | A0A347UR21 |
| Locus tag | OO778_RS07340 | Protein ID | WP_005398409.1 |
| Coordinates | 1565573..1565857 (-) | Length | 95 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| OO778_RS07300 (VspSTUT16_13430) | 1560795..1561478 | + | 684 | WP_256952285.1 | hypothetical protein | - |
| OO778_RS07305 | 1562106..1562195 | + | 90 | WP_079740859.1 | DUF3265 domain-containing protein | - |
| OO778_RS07310 | 1562641..1562733 | + | 93 | WP_264911200.1 | DUF3265 domain-containing protein | - |
| OO778_RS07315 | 1563351..1563443 | + | 93 | WP_264911379.1 | DUF3265 domain-containing protein | - |
| OO778_RS07320 (VspSTUT16_13450) | 1563477..1564076 | + | 600 | WP_264911202.1 | hypothetical protein | - |
| OO778_RS07325 (VspSTUT16_13470) | 1564204..1564611 | + | 408 | WP_104969514.1 | OsmC family protein | - |
| OO778_RS07330 | 1565180..1565269 | + | 90 | WP_072612530.1 | DUF3265 domain-containing protein | - |
| OO778_RS07335 (VspSTUT16_13480) | 1565298..1565576 | - | 279 | WP_264911205.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
| OO778_RS07340 (VspSTUT16_13490) | 1565573..1565857 | - | 285 | WP_005398409.1 | type II toxin-antitoxin system RelB/DinJ family antitoxin | Antitoxin |
| OO778_RS07345 | 1565934..1566025 | + | 92 | Protein_1369 | DUF3265 domain-containing protein | - |
| OO778_RS07350 | 1566383..1566517 | + | 135 | WP_264911207.1 | DUF3265 domain-containing protein | - |
| OO778_RS07355 | 1566600..1566722 | - | 123 | WP_264911209.1 | hypothetical protein | - |
| OO778_RS07360 (VspSTUT16_13510) | 1567114..1567413 | + | 300 | WP_229608461.1 | DUF2004 domain-containing protein | - |
| OO778_RS07365 | 1567442..1567534 | + | 93 | WP_078581101.1 | DUF3265 domain-containing protein | - |
| OO778_RS07370 | 1567915..1568027 | + | 113 | Protein_1374 | DUF3265 domain-containing protein | - |
| OO778_RS07375 (VspSTUT16_13520) | 1568056..1568715 | + | 660 | WP_061892966.1 | hypothetical protein | - |
| OO778_RS07380 | 1568706..1568768 | + | 63 | Protein_1376 | DUF3265 domain-containing protein | - |
| OO778_RS07385 (VspSTUT16_13530) | 1568873..1569226 | + | 354 | WP_031829440.1 | hypothetical protein | - |
| OO778_RS07390 | 1569241..1569333 | + | 93 | WP_006074995.1 | DUF3265 domain-containing protein | - |
| OO778_RS07395 | 1569778..1569846 | + | 69 | Protein_1379 | DUF3265 domain-containing protein | - |
| OO778_RS07400 | 1570358..1570450 | + | 93 | WP_005526494.1 | DUF3265 domain-containing protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Integrative and Conjugative Element | - | - | 1354859..1680644 | 325785 | |
| - | inside | Integron | - | - | 1559052..1640187 | 81135 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 93 a.a. Molecular weight: 10933.66 Da Isoelectric Point: 4.3430
>T42646 WP_264911205.1 NZ_AP026765:c1565576-1565298 [Vibrio sp. STUT-A16]
MILWEEESLNDREKIFEFLYDFNPDAAEKTDNLIEAKVENLLEQPLMGVQRDGIRGRLLIIPEISMIVSYWVEVDIIRVM
RVLHQKQKFPTD
MILWEEESLNDREKIFEFLYDFNPDAAEKTDNLIEAKVENLLEQPLMGVQRDGIRGRLLIIPEISMIVSYWVEVDIIRVM
RVLHQKQKFPTD
Download Length: 279 bp
>T42646 NZ_AP026765:c1565576-1565298 [Vibrio sp. STUT-A16]
ATGATTTTATGGGAAGAAGAGTCACTTAATGATCGTGAAAAGATCTTTGAGTTTCTCTATGACTTCAACCCTGATGCTGC
AGAAAAGACTGACAACCTCATTGAAGCAAAAGTAGAAAACTTACTTGAACAACCTTTAATGGGTGTGCAACGAGATGGCA
TCCGCGGACGATTACTCATCATTCCTGAGATTTCGATGATTGTATCTTACTGGGTTGAGGTCGATATCATCCGAGTTATG
CGTGTACTACACCAGAAACAAAAATTCCCTACGGATTGA
ATGATTTTATGGGAAGAAGAGTCACTTAATGATCGTGAAAAGATCTTTGAGTTTCTCTATGACTTCAACCCTGATGCTGC
AGAAAAGACTGACAACCTCATTGAAGCAAAAGTAGAAAACTTACTTGAACAACCTTTAATGGGTGTGCAACGAGATGGCA
TCCGCGGACGATTACTCATCATTCCTGAGATTTCGATGATTGTATCTTACTGGGTTGAGGTCGATATCATCCGAGTTATG
CGTGTACTACACCAGAAACAAAAATTCCCTACGGATTGA
Antitoxin
Download Length: 95 a.a. Molecular weight: 11069.40 Da Isoelectric Point: 9.2167
>AT42646 WP_005398409.1 NZ_AP026765:c1565857-1565573 [Vibrio sp. STUT-A16]
MDTRIQFRVDEETKRLAQQMAESQGRTLSDACRELTEQLAEQQRKTLSHDAWLTEQVNLAFEKFDSGKSVFVEHQTAKSR
MEERKARIRNRGKQ
MDTRIQFRVDEETKRLAQQMAESQGRTLSDACRELTEQLAEQQRKTLSHDAWLTEQVNLAFEKFDSGKSVFVEHQTAKSR
MEERKARIRNRGKQ
Download Length: 285 bp
>AT42646 NZ_AP026765:c1565857-1565573 [Vibrio sp. STUT-A16]
ATGGACACTAGAATTCAATTTCGTGTTGATGAAGAAACAAAACGCCTAGCTCAACAAATGGCTGAGAGCCAAGGTCGCAC
TCTGAGTGACGCATGCCGTGAACTTACTGAGCAACTCGCTGAACAACAAAGAAAAACATTATCTCACGATGCATGGCTAA
CTGAACAAGTAAACCTAGCATTTGAGAAGTTTGACTCAGGAAAATCCGTTTTCGTTGAGCACCAAACGGCTAAGTCTCGA
ATGGAAGAGCGCAAAGCCAGAATCCGTAATCGAGGTAAGCAATGA
ATGGACACTAGAATTCAATTTCGTGTTGATGAAGAAACAAAACGCCTAGCTCAACAAATGGCTGAGAGCCAAGGTCGCAC
TCTGAGTGACGCATGCCGTGAACTTACTGAGCAACTCGCTGAACAACAAAGAAAAACATTATCTCACGATGCATGGCTAA
CTGAACAAGTAAACCTAGCATTTGAGAAGTTTGACTCAGGAAAATCCGTTTTCGTTGAGCACCAAACGGCTAAGTCTCGA
ATGGAAGAGCGCAAAGCCAGAATCCGTAATCGAGGTAAGCAATGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|