Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/ParE-RHH
Location 1565114..1565652 Replicon chromosome
Accession NZ_AP026763
Organism Vibrio sp. STUT-A11

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag OO774_RS07460 Protein ID WP_264905903.1
Coordinates 1565114..1565413 (-) Length 100 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag OO774_RS07465 Protein ID WP_264905905.1
Coordinates 1565410..1565652 (-) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OO774_RS07430 1560646..1560783 + 138 WP_104971832.1 DUF3265 domain-containing protein -
OO774_RS07435 (VspSTUT11_13710) 1560811..1561287 + 477 WP_031812414.1 GNAT family N-acetyltransferase -
OO774_RS07440 (VspSTUT11_13720) 1562751..1562966 + 216 WP_228841545.1 hypothetical protein -
OO774_RS07445 1563127..1563177 + 51 WP_233263896.1 hypothetical protein -
OO774_RS07450 (VspSTUT11_13730) 1563198..1564397 - 1200 WP_264905900.1 IS4 family transposase -
OO774_RS07455 (VspSTUT11_13740) 1564565..1564999 + 435 WP_264905902.1 GNAT family N-acetyltransferase -
OO774_RS07460 (VspSTUT11_13750) 1565114..1565413 - 300 WP_264905903.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
OO774_RS07465 (VspSTUT11_13760) 1565410..1565652 - 243 WP_264905905.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
OO774_RS07470 1566232..1566417 + 186 WP_264906086.1 DUF3265 domain-containing protein -
OO774_RS07475 (VspSTUT11_13770) 1566420..1566854 + 435 WP_264905906.1 hypothetical protein -
OO774_RS07480 (VspSTUT11_13780) 1567245..1568270 - 1026 Protein_1396 IS110 family transposase -
OO774_RS07485 (VspSTUT11_13790) 1568553..1569581 + 1029 WP_264905110.1 IS110 family transposase -
OO774_RS07490 1569882..1570287 - 406 Protein_1398 DDE-type integrase/transposase/recombinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 1545070..1575680 30610
- inside Integron - - 1537735..1566854 29119


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-92)

Antitoxin

Antitoxin ParD

(4-72)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11634.36 Da        Isoelectric Point: 9.8628

>T42645 WP_264905903.1 NZ_AP026763:c1565413-1565114 [Vibrio sp. STUT-A11]
MKPFQLTNKAKSDLKDIALFTSRRWGREQRNIYLKQFDESFWLLAENPDIGKTCDEIKDGYRKFPQGSHVIFYQQIGSQN
IQIIRILHKSMDVNPIFGA

Download         Length: 300 bp

>T42645 NZ_AP026763:c1565413-1565114 [Vibrio sp. STUT-A11]
ATGAAACCATTCCAACTAACCAACAAGGCAAAATCCGATTTAAAAGATATTGCCTTATTTACCTCTCGCAGGTGGGGTCG
CGAGCAACGAAATATTTATCTCAAACAATTCGATGAATCATTTTGGCTACTCGCTGAAAATCCTGATATCGGTAAAACTT
GTGATGAAATCAAAGATGGCTACCGAAAATTTCCACAAGGAAGCCATGTGATTTTTTATCAGCAAATTGGTAGCCAAAAC
ATCCAGATCATAAGAATCTTGCATAAGAGTATGGATGTAAATCCAATCTTTGGCGCATAA

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 8929.85 Da        Isoelectric Point: 4.2213

>AT42645 WP_264905905.1 NZ_AP026763:c1565652-1565410 [Vibrio sp. STUT-A11]
MAKNTSITLGDHFDGFISSQIQSGRYGSASEVIRSALRLLETQETKMNTLRQLLVEGEESGLADYDLDSFISELDSEERK

Download         Length: 243 bp

>AT42645 NZ_AP026763:c1565652-1565410 [Vibrio sp. STUT-A11]
ATGGCTAAAAATACTAGCATCACTCTCGGCGACCACTTTGATGGTTTCATTAGTAGCCAAATCCAAAGTGGACGCTATGG
CTCAGCAAGTGAAGTAATTCGTTCCGCCCTACGTTTACTCGAAACACAAGAAACGAAAATGAACACTTTACGACAACTGC
TCGTTGAAGGTGAAGAAAGTGGTCTGGCTGATTATGACCTCGATTCGTTTATCAGTGAACTAGATAGCGAAGAAAGAAAA
TGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References