Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | relBE/ParE-YafN |
| Location | 1554823..1555351 | Replicon | chromosome |
| Accession | NZ_AP026763 | ||
| Organism | Vibrio sp. STUT-A11 | ||
Toxin (Protein)
| Gene name | relE | Uniprot ID | - |
| Locus tag | OO774_RS07390 | Protein ID | WP_264905861.1 |
| Coordinates | 1554823..1555113 (-) | Length | 97 a.a. |
Antitoxin (Protein)
| Gene name | relB | Uniprot ID | A0A347UR02 |
| Locus tag | OO774_RS07395 | Protein ID | WP_005377003.1 |
| Coordinates | 1555103..1555351 (-) | Length | 83 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| OO774_RS07345 | 1550767..1550895 | + | 129 | WP_264906084.1 | DUF3265 domain-containing protein | - |
| OO774_RS07350 (VspSTUT11_13580) | 1550923..1551432 | + | 510 | WP_031850736.1 | ClbS/DfsB family four-helix bundle protein | - |
| OO774_RS07355 | 1551447..1551539 | + | 93 | WP_005377014.1 | DUF3265 domain-containing protein | - |
| OO774_RS07360 (VspSTUT11_13590) | 1551560..1552759 | - | 1200 | WP_263837029.1 | IS4 family transposase | - |
| OO774_RS07365 (VspSTUT11_13600) | 1552890..1553207 | - | 318 | WP_026050327.1 | CcdB family protein | - |
| OO774_RS07370 (VspSTUT11_13610) | 1553207..1553452 | - | 246 | WP_026050326.1 | type II toxin-antitoxin system CcdA family antitoxin | - |
| OO774_RS07375 (VspSTUT11_13620) | 1553629..1554084 | + | 456 | WP_140210238.1 | GNAT family N-acetyltransferase | - |
| OO774_RS07380 (VspSTUT11_13630) | 1554378..1554593 | + | 216 | WP_228841545.1 | hypothetical protein | - |
| OO774_RS07385 | 1554754..1554804 | + | 51 | WP_233263896.1 | hypothetical protein | - |
| OO774_RS07390 (VspSTUT11_13640) | 1554823..1555113 | - | 291 | WP_264905861.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
| OO774_RS07395 (VspSTUT11_13650) | 1555103..1555351 | - | 249 | WP_005377003.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | Antitoxin |
| OO774_RS07400 (VspSTUT11_13660) | 1555549..1556151 | + | 603 | WP_264905894.1 | hypothetical protein | - |
| OO774_RS07405 | 1556369..1556728 | + | 360 | WP_264905895.1 | hypothetical protein | - |
| OO774_RS07410 (VspSTUT11_13670) | 1556944..1557639 | + | 696 | WP_264905896.1 | hypothetical protein | - |
| OO774_RS07415 (VspSTUT11_13680) | 1557769..1558968 | - | 1200 | WP_263837029.1 | IS4 family transposase | - |
| OO774_RS07420 (VspSTUT11_13690) | 1559121..1559492 | + | 372 | WP_264905898.1 | RidA family protein | - |
| OO774_RS07425 (VspSTUT11_13700) | 1559654..1560118 | + | 465 | WP_264905899.1 | ASCH domain-containing protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Genomic island | - | - | 1545070..1575680 | 30610 | |
| - | inside | Integron | - | - | 1537735..1566854 | 29119 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 97 a.a. Molecular weight: 11208.20 Da Isoelectric Point: 10.4077
>T42644 WP_264905861.1 NZ_AP026763:c1555113-1554823 [Vibrio sp. STUT-A11]
MTYKLDFKKSALKEWKKLGSTLQQQFKKKLIERLDNPHVPASKLSGADNMYKIKLRQSGYRLVYKVEDDVIIVTVLAVGK
RERSDVYCKAMKRLDD
MTYKLDFKKSALKEWKKLGSTLQQQFKKKLIERLDNPHVPASKLSGADNMYKIKLRQSGYRLVYKVEDDVIIVTVLAVGK
RERSDVYCKAMKRLDD
Download Length: 291 bp
>T42644 NZ_AP026763:c1555113-1554823 [Vibrio sp. STUT-A11]
ATGACCTATAAACTCGACTTTAAAAAGAGCGCACTCAAAGAGTGGAAGAAGCTTGGCTCTACTCTGCAACAACAATTTAA
GAAAAAGCTAATCGAGCGCTTAGATAACCCACATGTTCCGGCTTCAAAGCTTTCTGGAGCTGACAACATGTATAAAATTA
AGTTGCGGCAATCGGGCTACCGTCTCGTCTACAAAGTTGAAGACGATGTCATCATTGTAACCGTCTTAGCTGTCGGGAAA
CGCGAACGTAGCGATGTTTACTGTAAAGCTATGAAAAGGTTAGATGATTGA
ATGACCTATAAACTCGACTTTAAAAAGAGCGCACTCAAAGAGTGGAAGAAGCTTGGCTCTACTCTGCAACAACAATTTAA
GAAAAAGCTAATCGAGCGCTTAGATAACCCACATGTTCCGGCTTCAAAGCTTTCTGGAGCTGACAACATGTATAAAATTA
AGTTGCGGCAATCGGGCTACCGTCTCGTCTACAAAGTTGAAGACGATGTCATCATTGTAACCGTCTTAGCTGTCGGGAAA
CGCGAACGTAGCGATGTTTACTGTAAAGCTATGAAAAGGTTAGATGATTGA
Antitoxin
Download Length: 83 a.a. Molecular weight: 9079.37 Da Isoelectric Point: 3.9610
>AT42644 WP_005377003.1 NZ_AP026763:c1555351-1555103 [Vibrio sp. STUT-A11]
MTTRILADVAASITELKANPMKVATSAYGEPVAVLNRNEPAFYCVPAEAYEMMMDRLEDLELLAIAKERESEESISVNID
DL
MTTRILADVAASITELKANPMKVATSAYGEPVAVLNRNEPAFYCVPAEAYEMMMDRLEDLELLAIAKERESEESISVNID
DL
Download Length: 249 bp
>AT42644 NZ_AP026763:c1555351-1555103 [Vibrio sp. STUT-A11]
ATGACTACTAGAATTTTAGCCGATGTTGCTGCAAGCATTACTGAGTTGAAAGCTAACCCTATGAAAGTTGCAACTAGTGC
TTACGGCGAACCTGTTGCTGTACTAAACCGAAATGAGCCAGCATTTTATTGCGTACCTGCCGAAGCGTACGAAATGATGA
TGGACAGACTCGAAGATCTTGAACTACTAGCTATCGCTAAAGAGCGTGAATCTGAAGAGAGCATTTCGGTAAATATTGAT
GACCTATAA
ATGACTACTAGAATTTTAGCCGATGTTGCTGCAAGCATTACTGAGTTGAAAGCTAACCCTATGAAAGTTGCAACTAGTGC
TTACGGCGAACCTGTTGCTGTACTAAACCGAAATGAGCCAGCATTTTATTGCGTACCTGCCGAAGCGTACGAAATGATGA
TGGACAGACTCGAAGATCTTGAACTACTAGCTATCGCTAAAGAGCGTGAATCTGAAGAGAGCATTTCGGTAAATATTGAT
GACCTATAA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|