Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /DUF1778(antitoxin)
Location 1358519..1359411 Replicon chromosome
Accession NZ_AP026763
Organism Vibrio sp. STUT-A11

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag OO774_RS06500 Protein ID WP_264905660.1
Coordinates 1358878..1359411 (+) Length 178 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag OO774_RS06495 Protein ID WP_264905658.1
Coordinates 1358519..1358881 (+) Length 121 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OO774_RS06455 (VspSTUT11_11850) 1354060..1354569 + 510 WP_264905646.1 CbrC family protein -
OO774_RS06460 (VspSTUT11_11860) 1354724..1355137 + 414 WP_264905647.1 GIY-YIG nuclease family protein -
OO774_RS06465 (VspSTUT11_11870) 1355295..1355687 + 393 WP_264905649.1 hypothetical protein -
OO774_RS06470 1355714..1355806 + 93 WP_264905651.1 DUF3265 domain-containing protein -
OO774_RS06475 (VspSTUT11_11880) 1355902..1356117 + 216 WP_264905652.1 DUF4177 domain-containing protein -
OO774_RS06480 (VspSTUT11_11890) 1356138..1356344 + 207 WP_264905653.1 membrane protein insertion efficiency factor YidD -
OO774_RS06485 (VspSTUT11_11900) 1356344..1356733 + 390 WP_264905654.1 hypothetical protein -
OO774_RS06490 (VspSTUT11_11910) 1356988..1357230 + 243 WP_264905656.1 hypothetical protein -
OO774_RS06495 (VspSTUT11_11920) 1358519..1358881 + 363 WP_264905658.1 DUF1778 domain-containing protein Antitoxin
OO774_RS06500 (VspSTUT11_11930) 1358878..1359411 + 534 WP_264905660.1 GNAT family N-acetyltransferase Toxin
OO774_RS06505 (VspSTUT11_11940) 1359523..1360722 - 1200 WP_263837029.1 IS4 family transposase -
OO774_RS06510 (VspSTUT11_11950) 1360947..1361279 + 333 WP_264905622.1 type II toxin-antitoxin system RelE/ParE family toxin -
OO774_RS06515 (VspSTUT11_11960) 1361266..1361580 + 315 WP_089202944.1 DNA-binding transcriptional regulator -
OO774_RS06520 1362201..1362292 + 92 Protein_1204 DUF3265 domain-containing protein -
OO774_RS06525 (VspSTUT11_11970) 1362402..1363193 + 792 WP_264905662.1 PhzF family phenazine biosynthesis protein -
OO774_RS06530 1363193..1363318 + 126 WP_264905664.1 DUF3265 domain-containing protein -
OO774_RS06535 (VspSTUT11_11980) 1363345..1363779 + 435 WP_264905666.1 GNAT family N-acetyltransferase -
OO774_RS06540 (VspSTUT11_11990) 1363952..1364368 + 417 WP_264905668.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(97-153)

Antitoxin

Vibrio phage ICP1, Orf50

(36-112)


Sequences

Toxin        


Download         Length: 178 a.a.        Molecular weight: 20047.37 Da        Isoelectric Point: 9.6564

>T42638 WP_264905660.1 NZ_AP026763:1358878-1359411 [Vibrio sp. STUT-A11]
VSWGKEFVELSKSKHDRNSFDCGEQELNTFIKTQAAKHMQAGISRTMVLPSAQPLINQKFAICAFYSVAPSSISRETLPA
QLAKKLPKYPVPVFLLAQLAVHKEFHGSGLGKVSLIRALKYLWEVNHHMRAYAIVVDCLTDSAQAFYTKFGFEVLCEHNG
RIRMFLPMKTVEQLFNQ

Download         Length: 534 bp

>T42638 NZ_AP026763:1358878-1359411 [Vibrio sp. STUT-A11]
GTGAGTTGGGGTAAAGAGTTCGTAGAACTTAGTAAATCAAAGCATGACCGCAACTCATTTGACTGTGGTGAGCAAGAGCT
AAACACATTTATCAAAACTCAAGCTGCAAAGCACATGCAGGCAGGTATTAGTCGAACAATGGTTTTACCTAGTGCTCAAC
CACTGATAAATCAAAAATTCGCTATTTGTGCATTTTATAGTGTTGCCCCGAGTTCAATTAGCCGAGAAACATTACCGGCA
CAACTAGCAAAGAAACTTCCTAAATATCCAGTCCCTGTTTTTCTTTTGGCTCAATTAGCTGTGCACAAGGAGTTTCATGG
CTCTGGCCTTGGAAAGGTTAGTCTAATTCGTGCGCTGAAGTACTTGTGGGAAGTGAATCATCACATGAGGGCATACGCAA
TTGTTGTGGACTGTCTGACAGATTCCGCTCAAGCGTTCTATACGAAGTTCGGCTTTGAAGTATTGTGCGAGCACAATGGG
CGTATTCGTATGTTCTTGCCAATGAAAACGGTAGAACAGCTTTTTAATCAATAG

Antitoxin


Download         Length: 121 a.a.        Molecular weight: 13217.27 Da        Isoelectric Point: 4.9533

>AT42638 WP_264905658.1 NZ_AP026763:1358519-1358881 [Vibrio sp. STUT-A11]
MLRKLSVQIECALSLHYNLSGYGINPYIGGVMATARLDIRLDEEIKAKAEKASALLGLKSLTEYVVRLMDEDATHVIEEH
ESIMVKDSVFDEFMAACNKAKAPNQALLEAAKFADESGIK

Download         Length: 363 bp

>AT42638 NZ_AP026763:1358519-1358881 [Vibrio sp. STUT-A11]
TTGCTCCGTAAACTATCCGTACAAATTGAATGTGCTTTAAGTTTGCACTATAATCTTTCAGGTTACGGAATAAATCCGTA
CATAGGAGGGGTTATGGCAACAGCACGTTTAGATATCCGCCTTGATGAAGAGATCAAGGCAAAAGCCGAAAAAGCATCGG
CTTTACTTGGTTTAAAAAGTCTCACTGAATATGTAGTGAGGCTTATGGACGAAGATGCGACTCACGTTATTGAGGAGCAT
GAAAGTATTATGGTTAAAGACAGTGTCTTTGACGAGTTTATGGCTGCATGCAATAAAGCAAAAGCACCGAATCAAGCGTT
GCTTGAAGCTGCCAAATTTGCAGATGAGAGTGGTATTAAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References