Detailed information of TA system TA042633

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): ygfYX/Cpta(toxin)
• Location: 3506441..3507110
• Replicon: chromosome
• Accession: NZ_AP026732
• Organism: Shewanella xiamenensis strain NUITM-VS2

Toxin (Protein)

• Gene name: ygfX
• Uniprot ID: -
• Locus tag: OO995_RS15185
• Protein ID: WP_080612464.1
• Coordinates: 3506441..3506881 (-)
• Length: 147 a.a.

Antitoxin (Protein)

• Gene name: ygfY
• Uniprot ID: -
• Locus tag: OO995_RS15190
• Protein ID: WP_139122633.1
• Coordinates: 3506862..3507110 (-)
• Length: 83 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
OO995_RS15160 (NUITMVS2_29290)	3501855..3502328	-	474	WP_069454486.1	SoxR reducing system RseC family protein	-
OO995_RS15165 (NUITMVS2_29300)	3502340..3503272	-	933	WP_037427579.1	MucB/RseB C-terminal domain-containing protein	-
OO995_RS15170 (NUITMVS2_29310)	3503285..3503896	-	612	WP_264888967.1	RseA family anti-sigma factor	-
OO995_RS15175 (NUITMVS2_29320)	3503938..3504516	-	579	WP_037415584.1	RNA polymerase sigma factor RpoE	-
OO995_RS15180 (NUITMVS2_29330)	3504706..3506319	+	1614	WP_241406454.1	L-aspartate oxidase	-
OO995_RS15185	3506441..3506881	-	441	WP_080612464.1	hypothetical protein	Toxin
OO995_RS15190 (NUITMVS2_29340)	3506862..3507110	-	249	WP_139122633.1	succinate dehydrogenase assembly factor 2	Antitoxin
OO995_RS15195 (NUITMVS2_29350)	3507195..3508103	-	909	WP_069455412.1	transcriptional activator NhaR	-
OO995_RS15200 (NUITMVS2_29360)	3508198..3508584	-	387	WP_037415577.1	hypothetical protein	-
OO995_RS15205 (NUITMVS2_29370)	3508587..3509756	-	1170	WP_037415576.1	Na+/H+ antiporter NhaA	-
OO995_RS15210 (NUITMVS2_29380)	3509874..3510668	-	795	WP_264888968.1	thymidylate synthase	-
OO995_RS15215 (NUITMVS2_29390)	3510668..3511474	-	807	WP_037415571.1	prolipoprotein diacylglyceryl transferase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Inner membrane protein YgfX (5-134)

Antitoxin

• Flavinator of succinate dehydrogenase (7-77)

Sequences

Toxin

Protein

• Length: 147 a.a.
• Molecular weight: 16826.70 Da
• Isoelectric Point: 7.6899

>T42633 WP_080612464.1 NZ_AP026732:c3506881-3506441 [Shewanella xiamenensis]
VAELRHSFSVKASFDQRLSLVVFVCVCSTSLLLWPETDTAVLHGLRAILAVLILGFLCSQLWQLRKWHCRFELNGQGDGW
LSTGEAFHVLPRTWVTPFICLVYYQSADRLHLLPLWADMFSDTDYRHLCRLLLKVKTQAVSQHELL

Nucleotide

• Length: 441 bp

>T42633 NZ_AP026732:c3506881-3506441 [Shewanella xiamenensis]
GTGGCAGAGCTGCGCCATAGTTTTAGTGTAAAAGCCTCTTTTGACCAACGTCTCTCGTTGGTCGTATTTGTTTGTGTCTG
TAGCACTTCTTTACTTCTCTGGCCAGAAACGGATACCGCAGTACTACATGGACTGAGGGCTATACTCGCCGTCTTAATAT
TGGGATTCTTGTGCTCTCAGTTATGGCAACTGAGGAAATGGCATTGCCGTTTTGAGCTTAATGGTCAAGGAGACGGCTGG
CTATCAACGGGGGAGGCGTTTCATGTATTGCCCAGAACTTGGGTAACGCCGTTTATCTGCTTGGTTTACTATCAATCTGC
CGATAGGTTGCATCTCTTACCTCTATGGGCGGATATGTTTAGTGATACAGATTATCGCCACTTGTGCCGGCTATTACTTA
AAGTTAAAACTCAGGCGGTGAGCCAACACGAACTACTTTAA

Antitoxin

Protein

• Length: 83 a.a.
• Molecular weight: 9627.21 Da
• Isoelectric Point: 4.3440

>AT42633 WP_139122633.1 NZ_AP026732:c3507110-3506862 [Shewanella xiamenensis]
MELMNIARVRWACRRGMLELDVLFQPFVENVYQDLSDEDKALFIRLLECEDPELFAWFMGHEVCPDPELARMVVQVRGRA
AP

Nucleotide

• Length: 249 bp

>AT42633 NZ_AP026732:c3507110-3506862 [Shewanella xiamenensis]
TTGGAGTTAATGAACATTGCACGGGTCCGTTGGGCATGTCGCCGCGGAATGCTCGAATTAGACGTTTTGTTCCAGCCCTT
CGTTGAGAATGTGTATCAGGATTTGTCTGATGAAGATAAAGCCCTGTTTATTCGTTTACTCGAGTGTGAAGATCCTGAAT
TATTTGCATGGTTTATGGGTCATGAAGTTTGCCCTGATCCTGAGCTTGCCCGCATGGTAGTGCAAGTCCGTGGCAGAGCT
GCGCCATAG